(Q73353796)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10635319%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

title

The RAG1/RAG2 complex constitutes a 3' flap endonuclease: implications for junctional diversity in V(D)J and transpositional recombination (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10635319%20AND%20SRC:MED&resulttype=core&format=json

3'-flap endonuclease activity

3 November 2019

main subject

1 reference

Gene Ontology release 2020-05-02

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10635319%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

author name string

S Santagata

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10635319%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

E Besmer

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10635319%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

A Villa

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10635319%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

J S Allingham

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10635319%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

C Sobacchi

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10635319%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

D B Haniford

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10635319%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

P Vezzoni

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10635319%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

M C Nussenzweig

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10635319%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

Z Q Pan

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10635319%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

P Cortes

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10635319%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

publication date

1 December 1999

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10635319%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10635319%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

volume

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10635319%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10635319%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

page(s)

935-947

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10635319%20AND%20SRC:MED&resulttype=core&format=json

RAG1 and RAG2 form a stable postcleavage synaptic complex with DNA containing signal ends in V(D)J recombination

3 November 2019

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980223-3

7 January 2021

Transposition mediated by RAG1 and RAG2 and its implications for the evolution of the immune system

1 reference

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7 January 2021

The RAG1 homeodomain recruits HMG1 and HMG2 to facilitate recombination signal sequence binding and to enhance the intrinsic DNA-bending activity of RAG1-RAG2

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980223-3

7 January 2021

Distinct roles of RAG1 and RAG2 in binding the V(D)J recombination signal sequences

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980223-3

7 January 2021

Hairpin coding end opening is mediated by RAG1 and RAG2 proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980223-3

7 January 2021

The three chemical steps of Tn10/IS10 transposition involve repeated utilization of a single active site

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980223-3

7 January 2021

Extensive, nonrandom diversity of excision footprints generated by Ds-like transposon Ascot-1 suggests new parallels with V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980223-3

7 January 2021

DNA sequence and structure requirements for cleavage of V(D)J recombination signal sequences

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980223-3

7 January 2021

RAG1 mediates signal sequence recognition and recruitment of RAG2 in V(D)J recombination

1 reference

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7 January 2021

Initiation of V(D)J recombination in vitro obeying the 12/23 rule

1 reference

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7 January 2021

Detection of RAG protein-V(D)J recombination signal interactions near the site of DNA cleavage by UV cross-linking

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980223-3

7 January 2021

The composition of coding joints formed in V(D)J recombination is strongly affected by the nucleotide sequence of the coding ends and their relationship to the recombination signal sequences

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980223-3

7 January 2021

Mechanistic constraints on diversity in human V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980223-3

7 January 2021

Extent to which homology can constrain coding exon junctional diversity in V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980223-3

7 January 2021

The characterization of a mammalian DNA structure-specific endonuclease

1 reference

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7 January 2021

A stable RAG1-RAG2-DNA complex that is active in V(D)J cleavage

1 reference

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7 January 2021

Assembly of a 12/23 paired signal complex: a critical control point in V(D)J recombination

1 reference

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7 January 2021

DNA transposition by the RAG1 and RAG2 proteins: a possible source of oncogenic translocations

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980223-3

7 January 2021

Tn10 transposition via a DNA hairpin intermediate

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980223-3

7 January 2021

Functional analysis of coordinated cleavage in V(D)J recombination

1 reference

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7 January 2021

Increased frequency of N-region insertion in a murine pre-B-cell line infected with a terminal deoxynucleotidyl transferase retroviral expression vector

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980223-3

7 January 2021

Coding joint formation in a cell-free V(D)J recombination system

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980223-3

7 January 2021

The mechanism of V(D)J joining: lessons from molecular, immunological, and comparative analyses

1 reference

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7 January 2021

The biochemistry and biological significance of nonhomologous DNA end joining: an essential repair process in multicellular eukaryotes

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980223-3

7 January 2021

Identification of V(D)J recombination coding end intermediates in normal thymocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980223-3

7 January 2021

A flax transposon identified in two spontaneous mutant alleles of the L6 rust resistance gene

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980223-3

7 January 2021

Cleavage at a V(D)J recombination signal requires only RAG1 and RAG2 proteins and occurs in two steps

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980223-3

7 January 2021

Mutations in two Ku homologs define a DNA end-joining repair pathway in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980223-3

7 January 2021

RAG-1-deficient mice have no mature B and T lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980223-3

7 January 2021

Nucleotide deletion and P addition in V(D)J recombination: a determinant role of the coding-end sequence

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980223-3

7 January 2021

Footprint analysis of the RAG protein recombination signal sequence complex for V(D)J type recombination.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980223-3

7 January 2021

RAG-1 and RAG-2, adjacent genes that synergistically activate V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980223-3

7 January 2021

Nbs1 potentiates ATP-driven DNA unwinding and endonuclease cleavage by the Mre11/Rad50 complex

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980223-3

7 January 2021

Formation and resolution of double-strand break intermediates in V(D)J rearrangement

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980223-3

7 January 2021

Cell-free V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980223-3

7 January 2021

Characterization of broken DNA molecules associated with V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980223-3

7 January 2021

The effect of Me2+ cofactors at the initial stages of V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980223-3

7 January 2021

V(D)J recombination: modulation of RAG1 and RAG2 cleavage activity on 12/23 substrates by whole cell extract and DNA-bending proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980223-3

7 January 2021

The V(D)J recombination activating gene, RAG-1.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980223-3

7 January 2021

Structure of nonhairpin coding-end DNA breaks in cells undergoing V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980223-3

7 January 2021

Double-strand signal sequence breaks in V(D)J recombination are blunt, 5'-phosphorylated, RAG-dependent, and cell cycle regulated

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980223-3

7 January 2021

RAG mutations in human B cell-negative SCID.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980223-3

7 January 2021

RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980223-3

7 January 2021

DNA hairpin opening mediated by the RAG1 and RAG2 proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980223-3

7 January 2021

The homeodomain region of Rag-1 reveals the parallel mechanisms of bacterial and V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980223-3

7 January 2021

The 12/23 rule is enforced at the cleavage step of V(D)J recombination in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980223-3

7 January 2021

V(D)J recombination signal recognition: distinct, overlapping DNA-protein contacts in complexes containing RAG1 with and without RAG2.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980223-3

7 January 2021

RAG-2 promotes heptamer occupancy by RAG-1 in the assembly of a V(D)J initiation complex

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980223-3

7 January 2021

Somatic generation of antibody diversity

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980223-3

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980223-3

7 January 2021

Partial V(D)J recombination activity leads to Omenn syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980223-3

7 January 2021

The RAG-HMG1 complex enforces the 12/23 rule of V(D)J recombination specifically at the double-hairpin formation step

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980223-3

7 January 2021

10.1016/S1097-2765(00)80223-3

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10635319%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

1 reference