(Q73555532)

English

Distinct signaling requirements for Dmu selection, IgH allelic exclusion, pre-B cell transition, and tumor suppression in B cell progenitors

scientific article published on 01 June 2003

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scholarly article

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4 November 2019

Distinct signaling requirements for Dmu selection, IgH allelic exclusion, pre-B cell transition, and tumor suppression in B cell progenitors (English)

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4 November 2019

author name string

Katsuhiko Hayashi

1

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4 November 2019

Mutsumi Yamamoto

2

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4 November 2019

Takuya Nojima

3

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4 November 2019

Ryo Goitsuka

4

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4 November 2019

Daisuke Kitamura

5

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4 November 2019

publication date

1 June 2003

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4 November 2019

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4 November 2019

18

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4 November 2019

825-836

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4 November 2019

6

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4 November 2019

Frequency and characterization of phenotypic Ig heavy chain allelically included IgM-expressing B cells in mice.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900142-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Syk tyrosine kinase required for mouse viability and B-cell development

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900142-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Analysis of the B-cell progenitor compartment at the level of single cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900142-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Abnormal B lymphocyte development, activation, and differentiation in mice that lack or overexpress the CD19 signal transduction molecule.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900142-0

7 January 2021

based on heuristic

inferred from DOI database lookup

DNA double strand break repair and chromosomal translocation: lessons from animal models

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900142-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Pre-B cell receptor signaling mediates selective response to IL-7 at the pro-B to pre-B cell transition via an ERK/MAP kinase-dependent pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900142-0

7 January 2021

based on heuristic

inferred from DOI database lookup

BLNK: a central linker protein in B cell activation

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900142-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Regulation of an early developmental checkpoint in the B cell pathway by Ig beta.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900142-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Counterselection against D mu is mediated through immunoglobulin (Ig)alpha-Igbeta

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900142-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Spleen tyrosine kinase (Syk) deficiency in childhood pro-B cell acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900142-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Down-regulation of RAG1 and RAG2 gene expression in preB cells after functional immunoglobulin heavy chain rearrangement

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900142-0

7 January 2021

based on heuristic

inferred from DOI database lookup

B cell development regulated by gene rearrangement: arrest of maturation by membrane-bound D mu protein and selection of DH element reading frames

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900142-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Engagement of the human pre-B cell receptor generates a lipid raft-dependent calcium signaling complex

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900142-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Influence of surrogate L chain on DHJH-reading frame 2 suppression in mouse precursor B cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900142-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Resolution and characterization of pro-B and pre-pro-B cell stages in normal mouse bone marrow

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900142-0

7 January 2021

based on heuristic

inferred from DOI database lookup

The B cell-restricted adaptor BASH is required for normal development and antigen receptor-mediated activation of B cells

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900142-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Assembly of the truncated immunoglobulin heavy chain D mu into antigen receptor-like complexes in pre-B cells but not in B cells

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900142-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Only DFL16, DSP2, and DQ52 gene families exist in mouse immunoglobulin heavy chain diversity gene loci, of which DFL16 and DSP2 originate from the same primordial DH gene

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900142-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Control of B cell development by Ras-mediated activation of Raf.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900142-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Distinct signals mediate maturation and allelic exclusion in lymphocyte progenitors

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900142-0

7 January 2021

based on heuristic

inferred from DOI database lookup

BLNK required for coupling Syk to PLC gamma 2 and Rac1-JNK in B cells

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900142-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Abnormal development and function of B lymphocytes in mice deficient for the signaling adaptor protein SLP-65

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900142-0

7 January 2021

based on heuristic

inferred from DOI database lookup

The absence of SLP65 and Btk blocks B cell development at the preB cell receptor-positive stage

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900142-0

7 January 2021

based on heuristic

inferred from DOI database lookup

The expression of Vpre-B/lambda 5 surrogate light chain in early bone marrow precursor B cells of normal and B cell-deficient mutant mice

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900142-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Surrogate light chain in B cell development.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900142-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Defective B cell development and function in Btk-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900142-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Targeted disruption of mu chain membrane exon causes loss of heavy-chain allelic exclusion

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900142-0

7 January 2021

based on heuristic

inferred from DOI database lookup

A B cell-deficient mouse by targeted disruption of the membrane exon of the immunoglobulin mu chain gene

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900142-0

7 January 2021

based on heuristic

inferred from DOI database lookup

A critical role of λ5 protein in B cell development

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900142-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Targeted disruption of the MHC class II Aa gene in C57BL/6 mice

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900142-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Interference with immunoglobulin (Ig)alpha immunoreceptor tyrosine-based activation motif (ITAM) phosphorylation modulates or blocks B cell development, depending on the availability of an Igbeta cytoplasmic tail

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900142-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Surrogate Light Chain Expression Is Required to Establish Immunoglobulin Heavy Chain Allelic Exclusion during Early B Cell Development

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900142-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Truncated immunoglobulin Dmu causes incomplete developmental progression of RAG-deficient pro-B cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900142-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Feedback inhibition of immunoglobulin gene rearrangement by membrane mu, but not by secreted mu heavy chains

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900142-0

7 January 2021

based on heuristic

inferred from DOI database lookup

An essential role for BLNK in human B cell development

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900142-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Allelic exclusion in transgenic mice that express the membrane form of immunoglobulin mu

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900142-0

7 January 2021

based on heuristic

inferred from DOI database lookup

A human immunoglobulin gene reduces the incidence of lymphomas in c-Myc-bearing transgenic mice.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900142-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification of BSAP (Pax-5) target genes in early B-cell development by loss- and gain-of-function experiments

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900142-0

7 January 2021

based on heuristic

inferred from DOI database lookup

The cytoplasmic domains of immunoglobulin (Ig) alpha and Ig beta can independently induce the precursor B cell transition and allelic exclusion

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900142-0

7 January 2021

based on heuristic

inferred from DOI database lookup

The role of Ig beta in precursor B cell transition and allelic exclusion

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900142-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Surrogate or conventional light chains are required for membrane immunoglobulin mu to activate the precursor B cell transition

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900142-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Requirement for B cell linker protein (BLNK) in B cell development

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900142-0

7 January 2021

based on heuristic

inferred from DOI database lookup

A Prematurely Expressed Igκ Transgene, but Not a VκJκ Gene Segment Targeted into the Igκ Locus, Can Rescue B Cell Development in λ5-Deficient Mice

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900142-0

7 January 2021

based on heuristic

inferred from DOI database lookup

B cell progenitors are arrested in maturation but have intact VDJ recombination in the absence of Ig-alpha and Ig-beta

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900142-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Clonal selection and learning in the antibody system

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900142-0

7 January 2021

based on heuristic

inferred from DOI database lookup

B cell development is arrested at the immature B cell stage in mice carrying a mutation in the cytoplasmic domain of immunoglobulin beta

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900142-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Novel immunoglobulin heavy chains are produced from DJH gene segment rearrangements in lymphoid cells

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900142-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Impairment of T-cell-dependent B-cell responses and B-1 cell development in CD19-deficient mice.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900142-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Control of pre-BCR signaling by Pax5-dependent activation of the BLNK gene.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900142-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Activation of immunoglobulin kappa gene rearrangement correlates with induction of germline kappa gene transcription

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900142-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Virus-transformed pre-B cells show ordered activation but not inactivation of immunoglobulin gene rearrangement and transcription

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900142-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Induction of Ig light chain gene rearrangement in heavy chain-deficient B cells by activated Ras.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900142-0

7 January 2021

based on heuristic

inferred from DOI database lookup

VpreB1/VpreB2/lambda 5 triple-deficient mice show impaired B cell development but functional allelic exclusion of the IgH locus

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900142-0

7 January 2021

based on heuristic

inferred from DOI database lookup

The adaptor protein BLNK is required for b cell antigen receptor-induced activation of nuclear factor-kappa B and cell cycle entry and survival of B lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900142-0

7 January 2021

based on heuristic

inferred from DOI database lookup

The CD19-CD21 complex regulates signal transduction thresholds governing humoral immunity and autoimmunity

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900142-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Precursor B cells showing H chain allelic inclusion display allelic exclusion at the level of pre-B cell receptor surface expression

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900142-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Early function of Pax5 (BSAP) before the pre-B cell receptor stage of B lymphopoiesis

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900142-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Regulation of B lymphocyte development by the truncated immunoglobulin heavy chain protein Dmu.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900142-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Aberrant B Cell Development and Immune Response in Mice with a Compromised BCR Complex

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900142-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Cell surface expression of the short immunoglobulin mu chain (D mu protein) in murine pre-B cells is differently regulated from that of the intact mu chain

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900142-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Perinatal lethality and blocked B-cell development in mice lacking the tyrosine kinase Syk

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900142-0

7 January 2021

based on heuristic

inferred from DOI database lookup

SLP-65: a new signaling component in B lymphocytes which requires expression of the antigen receptor for phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900142-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Precursor B cells of mouse bone marrow express two different complexes with the surrogate light chain on the surface

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900142-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Cutting edge: B cell linker protein is dispensable for the allelic exclusion of immunoglobulin heavy chain locus but required for the persistence of CD5+ B cells

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900142-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/S1074-7613(03)00142-0

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12818163%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12818163%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

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