(Q74083363)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10918597%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

title

The c-MYC allele that is translocated into the IgH locus undergoes constitutive hypermutation in a Burkitt's lymphoma line (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10918597%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

author name string

Bemark M

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10918597%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

Neuberger MS

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10918597%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

language of work or name

English

0 references

publication date

1 July 2000

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10918597%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10918597%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

volume

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10918597%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

page(s)

3404-3410

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10918597%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

issue

30

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10918597%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/sj.onc.1203686

8 November 2019

exact match

0 references

cites work

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Sequence of the murine and human cellular myc oncogenes and two modes of myc transcription resulting from chromosome translocation in B lymphoid tumours.

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Elements regulating somatic hypermutation of an immunoglobulin κ gene: Critical role for the intron enhancer/matrix attachment region

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7 January 2021

Passenger transgenes reveal intrinsic specificity of the antibody hypermutation mechanism: clustering, polarity, and specific hot spots

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7 January 2021

Mutations in the first exon are associated with altered transcription of c-myc in Burkitt lymphoma

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7 January 2021

The c-myc gene encodes superimposed RNA polymerase II and III promoters

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7 January 2021

Human c-myc onc gene is located on the region of chromosome 8 that is translocated in Burkitt lymphoma cells

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7 January 2021

Mismatch repair deficiency interferes with the accumulation of mutations in chronically stimulated B cells and not with the hypermutation process

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7 January 2021

Somatic hypermutation in the heavy chain locus correlates with transcription.

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7 January 2021

Frequent occurrence of deletions and duplications during somatic hypermutation: implications for oncogene translocations and heavy chain disease

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7 January 2021

Cells strongly expressing Ig(kappa) transgenes show clonal recruitment of hypermutation: a role for both MAR and the enhancers.

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7 January 2021

c-Myc proteolysis by the ubiquitin-proteasome pathway: stabilization of c-Myc in Burkitt's lymphoma cells

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7 January 2021

Translocation joins c-myc and immunoglobulin gamma 1 genes in a Burkitt lymphoma revealing a third exon in the c-myc oncogene.

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7 January 2021

c-mycHypermutation in Burkitt's Lymphoma

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7 January 2021

Transcriptional pause, arrest and termination sites for RNA polymerase II in mammalian N- and c-myc genes

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7 January 2021

Intrinsic sites of transcription termination and pausing in the c-myc gene

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7 January 2021

Boundaries of somatic mutation in rearranged immunoglobulin genes: 5' boundary is near the promoter, and 3' boundary is approximately 1 kb from V(D)J gene

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7 January 2021

Frequent somatic hypermutation of the 5' noncoding region of the BCL6 gene in B-cell lymphoma

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7 January 2021

Somatic mutation and transcriptional deregulation of myc in endemic Burkitt's lymphoma disease: heptamer-nonamer recognition mistakes?

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Persistence of immunoglobulin heavy chain/c-myc recombination-positive lymphocyte clones in the blood of human immunodeficiency virus-infected homosexual men.

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7 January 2021

Reciprocal chromosome translocation between c-myc and immunoglobulin gamma 2b genes.

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7 January 2021

BCL-6 mutations in normal germinal center B cells: evidence of somatic hypermutation acting outside Ig loci

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7 January 2021

Somatic hypermutation of immunoglobulin genes is linked to transcription initiation

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7 January 2021

A second B cell-specific enhancer 3' of the immunoglobulin heavy-chain locus

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7 January 2021

Transcription enhancer identified near the human C mu immunoglobulin heavy chain gene is unavailable to the translocated c-myc gene in a Burkitt lymphoma.

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7 January 2021

Effect of somatic mutation within translocated c-myc genes in Burkitt's lymphoma.

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7 January 2021

Altered nucleotide sequences of a translocated c-myc gene in Burkitt lymphoma.

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7 January 2021

The 5' hypermutation boundary of kappa chains is independent of local and neighbouring sequences and related to the distance from the initiation of transcription.

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7 January 2021

Hot spot focusing of somatic hypermutation in MSH2-deficient mice suggests two stages of mutational targeting

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7 January 2021

TdT-accessible breaks are scattered over the immunoglobulin V domain in a constitutively hypermutating B cell line

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7 January 2021

Mutation of BCL-6 gene in normal B cells by the process of somatic hypermutation of Ig genes.

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7 January 2021

MYC oncogene involved in a t(8;22) chromosome translocation is not altered in its putative regulatory regions

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7 January 2021

The block to transcription elongation is promoter dependent in normal and Burkitt's lymphoma c-myc alleles

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7 January 2021

Allele-specific activation of the c-myc gene in an atypical Burkitt's lymphoma carrying the t(2;8) chromosomal translocation 250 kb downstream from c-myc

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7 January 2021

Translocation of the c-myc gene into the immunoglobulin heavy chain locus in human Burkitt lymphoma and murine plasmacytoma cells

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7 January 2021

Activation and somatic mutation of the translocated c-myc gene in burkitt lymphoma cells.

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7 January 2021

Characterization of the cis-acting elements required for somatic hypermutation of murine antibody V genes using conventional transgenic and transgene homologous recombination approaches

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7 January 2021

The transcriptional promoter regulates hypermutation of the antibody heavy chain locus

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7 January 2021

Somatic hypermutation of Ig genes in patients with xeroderma pigmentosum (XP-D)

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7 January 2021

Somatic hypermutation of immunoglobulin genes

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7 January 2021

Somatic hypermutation introduces insertions and deletions into immunoglobulin V genes

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7 January 2021

Activation of a translocated c-myc gene: role of structural alterations in the upstream region

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7 January 2021

Targeting of non-Ig sequences in place of the V segment by somatic hypermutation.

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7 January 2021

A point mutation in the c-myc locus of a Burkitt lymphoma abolishes binding of a nuclear protein.

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7 January 2021