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A 3' enhancer in the IL-4 gene regulates cytokine production by Th2 cells and mast cells
scientific article published on 01 July 2002
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
12150890
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12150890%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 November 2019
title
A 3' enhancer in the IL-4 gene regulates cytokine production by Th2 cells and mast cells
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
12150890
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12150890%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 November 2019
main subject
mast cell
1 reference
based on heuristic
inferred from title
author
Anjana Rao
series ordinal
5
object named as
Anjana Rao
1 reference
stated in
Europe PubMed Central
PubMed ID
12150890
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12150890%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 November 2019
author name string
Deborah C Solymar
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
12150890
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12150890%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 November 2019
Suneet Agarwal
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed ID
12150890
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12150890%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 November 2019
Craig H Bassing
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed ID
12150890
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12150890%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 November 2019
Frederick W Alt
series ordinal
4
1 reference
stated in
Europe PubMed Central
PubMed ID
12150890
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12150890%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 November 2019
publication date
1 July 2002
1 reference
stated in
Europe PubMed Central
PubMed ID
12150890
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12150890%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 November 2019
published in
Immunity
1 reference
stated in
Europe PubMed Central
PubMed ID
12150890
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12150890%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 November 2019
volume
17
1 reference
stated in
Europe PubMed Central
PubMed ID
12150890
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12150890%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 November 2019
page(s)
41-50
1 reference
stated in
Europe PubMed Central
PubMed ID
12150890
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12150890%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 November 2019
issue
1
1 reference
stated in
Europe PubMed Central
PubMed ID
12150890
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12150890%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 November 2019
cites work
Modulation of chromatin structure regulates cytokine gene expression during T cell differentiation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900334-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cell-type-restricted binding of the transcription factor NFAT to a distal IL-4 enhancer in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900334-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
T cell differentiation: a mechanistic view
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900334-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Multiple developmental stage-specific enhancers regulate CD8 expression in developing thymocytes and in thymus-independent T cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900334-5
retrieved
7 January 2021
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inferred from DOI database lookup
Computational and biological analysis of 680 kb of DNA sequence from the human 5q31 cytokine gene cluster region
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900334-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
New concepts about the mast cell
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900334-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mast cell clones: a model for the analysis of cellular maturation
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900334-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Ig(kappa) enhancer influences the ratio of Ig(kappa) versus Ig(lambda) B lymphocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900334-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
PU.1 and GATA: components of a mast cell-specific interleukin 4 intronic enhancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900334-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hyperproliferation and dysregulation of IL-4 expression in NF-ATp-deficient mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900334-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A region in the CD8 gene locus that directs expression to the mature CD8 T cell subset in transgenic mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900334-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An intron transcriptional enhancer element regulates IL-4 gene locus accessibility in mast cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900334-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Stat6 is required for mediating responses to IL-4 and for development of Th2 cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900334-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Down-regulation of IL-4 gene transcription and control of Th2 cell differentiation by a mechanism involving NFAT1
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900334-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The transcription factor c-Maf controls the production of interleukin-4 but not other Th2 cytokines
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900334-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Heterogeneity of mast cells and phenotypic change between subpopulations
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900334-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
KIF3A is a new microtubule-based anterograde motor in the nerve axon
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900334-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of IL-4 gene expression by distal regulatory elements and GATA-3 at the chromatin level
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900334-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Th2 lineage commitment and efficient IL-4 production involves extended demethylation of the IL-4 gene.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900334-5
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7 January 2021
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Identification of a Coordinate Regulator of Interleukins 4, 13, and 5 by Cross-Species Sequence Comparisons
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900334-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Expression of NFAT-family proteins in normal human T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900334-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression of an erythroid transcription factor in megakaryocytic and mast cell lineages
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900334-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mast cells in innate immunity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900334-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Deletion of a coordinate regulator of type 2 cytokine expression in mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900334-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900334-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Signaling and transcription in T helper development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900334-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Fate of bone marrow-derived cultured mast cells after intracutaneous, intraperitoneal, and intravenous transfer into genetically mast cell-deficient W/Wv mice. Evidence that cultured mast cells can give rise to both connective tissue type and mucosa
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900334-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cytokines induce the development of functionally heterogeneous T helper cell subsets
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900334-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The molecular basis of T helper 1 and T helper 2 cell differentiation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900334-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
NFATc1 and NFATc2 together control both T and B cell activation and differentiation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900334-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lymphokine production by human T cells in disease states
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900334-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The presence of interleukin 4 during in vitro priming determines the lymphokine-producing potential of CD4+ T cells from T cell receptor transgenic mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900334-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Immunosuppressive drugs prevent a rapid dephosphorylation of transcription factor NFAT1 in stimulated immune cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900334-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of immunity to parasites by T cells and T cell-derived cytokines
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900334-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
STAT6-independent production of IL-4 by mast cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900334-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Essential role of Stat6 in IL-4 signalling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900334-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Th2-specific DNase I-hypersensitive sites in the murine IL-13 and IL-4 intergenic region.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900334-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Eosinophils: biology and role in disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900334-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of IL-4 production in mast cells: a paradigm for cell-type-specific gene expression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900334-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An enhanced immune response in mice lacking the transcription factor NFAT1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900334-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cooperative DNA binding and sequence-selective recognition conferred by the STAT amino-terminal domain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900334-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of allergic inflammation in a murine model of asthma by expression of a dominant-negative mutant of GATA-3
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900334-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900334-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interleukin 13, an interleukin 4-like cytokine that acts on monocytes and B cells, but not on T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2802%2900334-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S1074-7613(02)00334-5
1 reference
stated in
Europe PubMed Central
PubMed ID
12150890
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12150890%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 November 2019
PubMed ID
12150890
1 reference
stated in
Europe PubMed Central
PubMed ID
12150890
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12150890%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 November 2019
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