(Q7671480)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q8TD43

transient receptor potential channel

1 reference

Transporter Classification Database ID

1.A.4.5.4

hierarchical database ID heuristic

2 October 2019

based on heuristic

Ion transport domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TD43

calcium channel activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TD43

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TD43

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TD43

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8TD43&geneProductId=UniProtKB:Q8TD43

sodium channel activity

1 reference

7 November 2018

calcium activated cation channel activity

TAS

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TD43

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TD43

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TD43

8 April 2019

Electron cryo-microscopy structure of a human TRPM4 channel

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TD43

8 April 2019

Variants of Transient Receptor Potential Melastatin Member 4 in Childhood Atrioventricular Block

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TD43

1 reference

8 April 2019

Structure of the human TRPM4 ion channel in a lipid nanodisc

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TD43

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TD43

2 references

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TD43

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TD43

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TD43

8 April 2019

Cloning and characterization of rat transient receptor potential-melastatin 4 (TRPM4)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TD43

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TD43

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TD43

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TD43

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TD43

Variants of Transient Receptor Potential Melastatin Member 4 in Childhood Atrioventricular Block

sodium channel complex

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TD43

spanning component of membrane

1 reference

8 April 2019

Structure of the human TRPM4 ion channel in a lipid nanodisc

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TD43

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TD43

biological process

adaptive immune response

1 reference

8 April 2019

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TD43

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TD43

immune system process

1 reference

8 April 2019

positive regulation of canonical Wnt signaling pathway

1 reference

8 April 2019

TRPM4 enhances cell proliferation through up-regulation of the β-catenin signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TD43

regulation of membrane potential

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TD43

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TD43

1 reference

8 April 2019

Impaired endocytosis of the ion channel TRPM4 is associated with human progressive familial heart block type I

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TD43

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TD43

positive regulation of cell population proliferation

1 reference

8 April 2019

TRPM4 enhances cell proliferation through up-regulation of the β-catenin signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TD43

calcium ion transport

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TD43

negative regulation of bone mineralization

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TD43

positive regulation of atrial cardiac muscle cell action potential

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TD43

positive regulation of heart rate

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TD43

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TD43

transmembrane transport

1 reference

8 April 2019

positive regulation of adipose tissue development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TD43

positive regulation of cytosolic calcium ion concentration

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TD43

calcium ion transmembrane transport

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TD43

positive regulation of fat cell differentiation

TAS

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TD43

positive regulation of insulin secretion involved in cellular response to glucose stimulus

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TD43

negative regulation of osteoblast differentiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TD43

positive regulation of vasoconstriction

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TD43

positive regulation of regulation of vascular associated smooth muscle cell membrane depolarization

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TD43

ion transmembrane transport

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TD43

calcium-mediated signaling

1 reference

8 April 2019

Variants of Transient Receptor Potential Melastatin Member 4 in Childhood Atrioventricular Block

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TD43

membrane depolarization during AV node cell action potential

1 reference

8 April 2019

Variants of Transient Receptor Potential Melastatin Member 4 in Childhood Atrioventricular Block

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TD43

membrane depolarization during Purkinje myocyte cell action potential

1 reference

8 April 2019

Variants of Transient Receptor Potential Melastatin Member 4 in Childhood Atrioventricular Block

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TD43

membrane depolarization during bundle of His cell action potential

1 reference

8 April 2019

Variants of Transient Receptor Potential Melastatin Member 4 in Childhood Atrioventricular Block

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TD43

regulation of heart rate by cardiac conduction

1 reference

8 April 2019

Variants of Transient Receptor Potential Melastatin Member 4 in Childhood Atrioventricular Block

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TD43

sodium ion import across plasma membrane

1 reference

8 April 2019

Variants of Transient Receptor Potential Melastatin Member 4 in Childhood Atrioventricular Block

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TD43

regulation of ventricular cardiac muscle cell action potential

1 reference

8 April 2019

Variants of Transient Receptor Potential Melastatin Member 4 in Childhood Atrioventricular Block

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TD43

protein homotetramerization

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TD43

8 April 2019

Structure of the human TRPM4 ion channel in a lipid nanodisc

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TD43

8 April 2019

Electron cryo-microscopy structure of a human TRPM4 channel

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TD43

cellular response to ATP

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TD43

physically interacts with

adenosine triphosphate

has use

channel blocker

1 reference

1713

17 August 2016

1 reference

710

17 August 2016

1 reference

2844

English

17 August 2016

adenosine monophosphate

1 reference

2455

English

17 August 2016

adenosine diphosphate

1 reference

1712

17 August 2016

1 reference

2456

17 August 2016

1 reference

2330

17 August 2016

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q8TD43

Identifiers

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

Transporter Classification Database ID

1.A.4.5.4

2 references

Transporter Classification database

13 March 2020

Transporter Classification database