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Hypoxia-inducible factor 1: master regulator of O2 homeostasis
scientific article published on 01 October 1998
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
9794818
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9794818%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 December 2019
review article
1 reference
stated in
Europe PubMed Central
title
Hypoxia-inducible factor 1: master regulator of O2 homeostasis
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
9794818
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9794818%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 December 2019
author
Gregg L. Semenza
series ordinal
1
object named as
G L Semenza
1 reference
stated in
Europe PubMed Central
PubMed ID
9794818
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9794818%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 December 2019
publication date
1 October 1998
1 reference
stated in
Europe PubMed Central
PubMed ID
9794818
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9794818%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 December 2019
published in
Current Opinion in Genetics & Development
1 reference
stated in
Europe PubMed Central
PubMed ID
9794818
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9794818%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 December 2019
volume
8
1 reference
stated in
Europe PubMed Central
PubMed ID
9794818
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9794818%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 December 2019
page(s)
588-594
1 reference
stated in
Europe PubMed Central
PubMed ID
9794818
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9794818%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 December 2019
issue
5
1 reference
stated in
Europe PubMed Central
PubMed ID
9794818
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9794818%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 December 2019
cites work
Functional analysis of an oxygen-regulated transcriptional enhancer lying 3' to the mouse erythropoietin gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980016-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hypoxia-inducible nuclear factors bind to an enhancer element located 3' to the human erythropoietin gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980016-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980016-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Purification and characterization of hypoxia-inducible factor 1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980016-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980016-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hypoxia-inducible factor 1 levels vary exponentially over a physiologically relevant range of O2 tension
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980016-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of hypoxia-inducible factor 1alpha: posttranscriptional regulation and conformational change by recruitment of the Arnt transcription factor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980016-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cardiac expressions of HIF-1 alpha and HLF/EPAS, two basic loop helix/PAS domain transcription factors involved in adaptative responses to hypoxic stresses
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980016-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Induction of phosphoglycerate kinase 1 gene expression by hypoxia. Roles of Arnt and HIF1alpha
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980016-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nucleotide sequence, chromosomal assignment and mRNA expression of mouse hypoxia-inducible factor-1 alpha
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980016-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The mouse gene for hypoxia-inducible factor-1alpha--genomic organization, expression and characterization of an alternative first exon and 5' flanking sequence
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980016-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The human hypoxia-inducible factor 1alpha gene: HIF1A structure and evolutionary conservation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980016-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
In vivo expression of mRNAs encoding hypoxia-inducible factor 1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980016-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hypoxia Response Elements in the Aldolase A, Enolase 1, and Lactate Dehydrogenase A Gene Promoters Contain Essential Binding Sites for Hypoxia-inducible Factor 1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980016-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alpha
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980016-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Abnormal angiogenesis and responses to glucose and oxygen deprivation in mice lacking the protein ARNT.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980016-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of hypoxia-inducible transcription factor depends primarily upon redox-sensitive stabilization of its alpha subunit
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980016-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dimerization, DNA binding, and transactivation properties of hypoxia-inducible factor 1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980016-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hypoxia-inducible factor 1alpha (HIF-1alpha) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions. Its stabilization by hypoxia depends on redox-induced changes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980016-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transactivation and inhibitory domains of hypoxia-inducible factor 1alpha. Modulation of transcriptional activity by oxygen tension
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980016-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of Hypoxia-inducible Factor-1; Definition of Regulatory Domains within the α Subunit
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980016-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effect of protein kinase and phosphatase inhibitors on expression of hypoxia-inducible factor 1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980016-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effect of altered redox states on expression and DNA-binding activity of hypoxia-inducible factor 1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980016-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cobalt and desferrioxamine reveal crucial members of the oxygen sensing pathway in HepG2 cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980016-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cobalt chloride and desferrioxamine antagonize the inhibition of erythropoietin production by reactive oxygen species.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980016-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Diphenylene iodonium inhibits the induction of erythropoietin and other mammalian genes by hypoxia. Implications for the mechanism of oxygen sensing
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980016-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of hydrogen peroxide in hypoxia-induced erythropoietin production
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980016-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cellular respiration during hypoxia. Role of cytochrome oxidase as the oxygen sensor in hepatocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980016-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Selection and analysis of a mutant cell line defective in the hypoxia-inducible factor-1 alpha-subunit (HIF-1alpha). Characterization of hif-1alpha-dependent and -independent hypoxia-inducible gene expression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980016-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cardiac hypertrophy in chronically anemic fetal sheep: Increased vascularization is associated with increased myocardial expression of vascular endothelial growth factor and hypoxia-inducible factor 1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980016-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980016-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The role of the aryl hydrocarbon receptor nuclear translocator (ARNT) in hypoxic induction of gene expression. Studies in ARNT-deficient cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980016-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Absolute requirement of aryl hydrocarbon receptor nuclear translocator protein for gene activation by hypoxia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980016-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hypoxia-inducible factor-1 modulates gene expression in solid tumors and influences both angiogenesis and tumor growth.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980016-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
ARNT-deficient mice and placental differentiation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980016-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
In vitro analysis of Ah receptor domains involved in ligand-activated DNA recognition
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980016-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The murine Sim-2 gene product inhibits transcription by active repression and functional interference
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980016-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A novel bHLH-PAS factor with close sequence similarity to hypoxia-inducible factor 1alpha regulates the VEGF expression and is potentially involved in lung and vascular development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980016-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
HRF, a putative basic helix-loop-helix-PAS-domain transcription factor is closely related to hypoxia-inducible factor-1 alpha and developmentally expressed in blood vessels
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980016-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of a subset of the basic-helix-loop-helix-PAS superfamily that interacts with components of the dioxin signaling pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980016-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980016-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
cDNA cloning and tissue-specific expression of a novel basic helix-loop-helix/PAS factor (Arnt2) with close sequence similarity to the aryl hydrocarbon receptor nuclear translocator (Arnt)
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980016-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Angiogenesis by gene therapy: a new horizon for myocardial revascularization?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980016-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Oxygen-regulated transferrin expression is mediated by hypoxia-inducible factor-1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980016-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hypoxia-induced transcriptional activation and increased mRNA stability of vascular endothelial growth factor in C6 glioma cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980016-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transcriptional regulation of the rat vascular endothelial growth factor gene by hypoxia.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980016-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hypoxia regulates vascular endothelial growth factor gene expression in endothelial cells. Identification of a 5' enhancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980016-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A hypoxia-responsive element mediates a novel pathway of activation of the inducible nitric oxide synthase promoter
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980016-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hypoxia-inducible Factor-1 Mediates Transcriptional Activation of the Heme Oxygenase-1 Gene in Response to Hypoxia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980016-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hypoxia and mitochondrial inhibitors regulate expression of glucose transporter-1 via distinct Cis-acting sequences
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980016-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Oxygen-regulated control elements in the phosphoglycerate kinase 1 and lactate dehydrogenase A genes: similarities with the erythropoietin 3' enhancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980016-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hypoxic Regulation of Lactate Dehydrogenase A
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980016-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0959-437X(98)80016-6
1 reference
stated in
Europe PubMed Central
PubMed ID
9794818
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9794818%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 December 2019
PubMed ID
9794818
1 reference
stated in
Europe PubMed Central
PubMed ID
9794818
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9794818%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 December 2019
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