(Q77614144)

English

Limits to lifespan

scientific article published on 01 February 2002

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scholarly article

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11835050%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

Limits to lifespan (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11835050%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

1 reference

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author name string

Alison C Lloyd

1

1 reference

Europe PubMed Central

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7 December 2019

publication date

1 February 2002

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Europe PubMed Central

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7 December 2019

Nature Cell Biology

1 reference

Europe PubMed Central

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7 December 2019

4

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7 December 2019

E25-7

1 reference

Europe PubMed Central

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7 December 2019

2

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Europe PubMed Central

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7 December 2019

https://scigraph.springernature.com/pub.10.1038/ncb0202-e25

0 references

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

1 reference

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7 January 2021

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DNA damage triggers a prolonged p53-dependent G1 arrest and long-term induction of Cip1 in normal human fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FNCB0202-E25

7 January 2021

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Role of ceramide in cellular senescence

1 reference

https://api.crossref.org/works/10.1038%2FNCB0202-E25

7 January 2021

based on heuristic

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Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

1 reference

https://api.crossref.org/works/10.1038%2FNCB0202-E25

7 January 2021

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Inhibitors of cyclin-dependent kinases induce features of replicative senescence in early passage human diploid fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FNCB0202-E25

7 January 2021

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THE LIMITED IN VITRO LIFETIME OF HUMAN DIPLOID CELL STRAINS

1 reference

https://api.crossref.org/works/10.1038%2FNCB0202-E25

7 January 2021

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Cap-prevented recombination between terminal telomeric repeat arrays (telomere CPR) maintains telomeres in Kluyveromyces lactis lacking telomerase

1 reference

https://api.crossref.org/works/10.1038%2FNCB0202-E25

7 January 2021

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TRF2 Protects Human Telomeres from End-to-End Fusions

1 reference

https://api.crossref.org/works/10.1038%2FNCB0202-E25

7 January 2021

based on heuristic

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Extension of life-span by introduction of telomerase into normal human cells

1 reference

https://api.crossref.org/works/10.1038%2FNCB0202-E25

7 January 2021

based on heuristic

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Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells.

1 reference

https://api.crossref.org/works/10.1038%2FNCB0202-E25

7 January 2021

based on heuristic

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Telomere shortening and tumor formation by mouse cells lacking telomerase RNA

1 reference

https://api.crossref.org/works/10.1038%2FNCB0202-E25

7 January 2021

based on heuristic

inferred from DOI database lookup

Cellular senescence: mitotic clock or culture shock?

1 reference

https://api.crossref.org/works/10.1038%2FNCB0202-E25

7 January 2021

based on heuristic

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Telomere dynamics in cancer progression and prevention: fundamental differences in human and mouse telomere biology

1 reference

https://api.crossref.org/works/10.1038%2FNCB0202-E25

7 January 2021

based on heuristic

inferred from DOI database lookup

Lack of replicative senescence in normal rodent glia

1 reference

https://api.crossref.org/works/10.1038%2FNCB0202-E25

7 January 2021

based on heuristic

inferred from DOI database lookup

Lack of replicative senescence in cultured rat oligodendrocyte precursor cells

1 reference

https://api.crossref.org/works/10.1038%2FNCB0202-E25

7 January 2021

based on heuristic

inferred from DOI database lookup

Extended culture of mouse embryo cells without senescence: inhibition by serum.

1 reference

https://api.crossref.org/works/10.1038%2FNCB0202-E25

7 January 2021

based on heuristic

inferred from DOI database lookup

Differentiation of serum-free mouse embryo cells into astrocytes is accompanied by induction of glutamine synthetase activity

1 reference

https://api.crossref.org/works/10.1038%2FNCB0202-E25

7 January 2021

based on heuristic

inferred from DOI database lookup

Putative telomere-independent mechanisms of replicative aging reflect inadequate growth conditions

1 reference

https://api.crossref.org/works/10.1038%2FNCB0202-E25

7 January 2021

based on heuristic

inferred from DOI database lookup

p19ARF links the tumour suppressor p53 to Ras

1 reference

https://api.crossref.org/works/10.1038%2FNCB0202-E25

7 January 2021

based on heuristic

inferred from DOI database lookup

Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FNCB0202-E25

7 January 2021

based on heuristic

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Loss of p16Ink4a confers susceptibility to metastatic melanoma in mice

1 reference

https://api.crossref.org/works/10.1038%2FNCB0202-E25

7 January 2021

based on heuristic

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Loss of p16Ink4a with retention of p19Arf predisposes mice to tumorigenesis

1 reference

https://api.crossref.org/works/10.1038%2FNCB0202-E25

7 January 2021

based on heuristic

inferred from DOI database lookup

Telomere states and cell fates.

1 reference

https://api.crossref.org/works/10.1038%2FNCB0202-E25

7 January 2021

based on heuristic

inferred from DOI database lookup

Agents that cause DNA double strand breaks lead to p16INK4a enrichment and the premature senescence of normal fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FNCB0202-E25

7 January 2021

based on heuristic

inferred from DOI database lookup

Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling

1 reference

https://api.crossref.org/works/10.1038%2FNCB0202-E25

7 January 2021

based on heuristic

inferred from DOI database lookup

Senescence of human fibroblasts induced by oncogenic Raf.

1 reference

https://api.crossref.org/works/10.1038%2FNCB0202-E25

7 January 2021

based on heuristic

inferred from DOI database lookup

Opposing effects of Ets and Id proteins on p16INK4a expression during cellular senescence

1 reference

https://api.crossref.org/works/10.1038%2FNCB0202-E25

7 January 2021

based on heuristic

inferred from DOI database lookup

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