(Q80034682)

English

Mcl-1, Bcl-XL and Stat3 expression are associated with progression of melanoma whereas Bcl-2, AP-2 and MITF levels decrease during progression of melanoma

scientific article published on 01 April 2007

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scholarly article

1 reference

Europe PubMed Central

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28 December 2019

Mcl-1, Bcl-XL and Stat3 expression are associated with progression of melanoma whereas Bcl-2, AP-2 and MITF levels decrease during progression of melanoma (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17384650%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

Richard Scolyer

3

1 reference

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28 December 2019

5

1 reference

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28 December 2019

author name string

Liqing Zhuang

1

1 reference

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28 December 2019

C Soon Lee

2

1 reference

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28 December 2019

Stanley W McCarthy

4

1 reference

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28 December 2019

John F Thompson

6

1 reference

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28 December 2019

Peter Hersey

7

1 reference

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28 December 2019

publication date

1 April 2007

1 reference

Europe PubMed Central

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28 December 2019

Modern Pathology

1 reference

Europe PubMed Central

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28 December 2019

20

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28 December 2019

416-426

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28 December 2019

4

1 reference

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28 December 2019

https://scigraph.springernature.com/pub.10.1038/modpathol.3800750

0 references

The Bcl2 family: regulators of the cellular life-or-death switch

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.3800750

7 January 2021

based on heuristic

inferred from DOI database lookup

BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.3800750

7 January 2021

based on heuristic

inferred from DOI database lookup

Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.3800750

7 January 2021

based on heuristic

inferred from DOI database lookup

Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.3800750

7 January 2021

based on heuristic

inferred from DOI database lookup

Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.3800750

7 January 2021

based on heuristic

inferred from DOI database lookup

Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.3800750

7 January 2021

based on heuristic

inferred from DOI database lookup

Involvement of the bcl-2 gene in human follicular lymphoma

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.3800750

7 January 2021

based on heuristic

inferred from DOI database lookup

MCL1, a gene expressed in programmed myeloid cell differentiation, has sequence similarity to BCL2

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.3800750

7 January 2021

based on heuristic

inferred from DOI database lookup

bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.3800750

7 January 2021

based on heuristic

inferred from DOI database lookup

Bcl-xl antisense treatment induces apoptosis in breast carcinoma cells

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.3800750

7 January 2021

based on heuristic

inferred from DOI database lookup

Bcl-xL is expressed in ovarian carcinoma and modulates chemotherapy-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.3800750

7 January 2021

based on heuristic

inferred from DOI database lookup

Induction of apoptosis in lung-cancer cells following bcl-xL anti-sense treatment.

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.3800750

7 January 2021

based on heuristic

inferred from DOI database lookup

Antiapoptotic bcl-2 and bcl-xL in advanced malignant melanoma

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.3800750

7 January 2021

based on heuristic

inferred from DOI database lookup

Bcl-2 and bcl-xL antisense oligonucleotides induce apoptosis in melanoma cells of different clinical stages

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.3800750

7 January 2021

based on heuristic

inferred from DOI database lookup

Bcl-XL is a chemoresistance factor in human melanoma cells that can be inhibited by antisense therapy

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.3800750

7 January 2021

based on heuristic

inferred from DOI database lookup

The role of cell cycle regulatory proteins in the pathogenesis of melanoma.

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.3800750

7 January 2021

based on heuristic

inferred from DOI database lookup

Mechanisms of hair graying: incomplete melanocyte stem cell maintenance in the niche

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.3800750

7 January 2021

based on heuristic

inferred from DOI database lookup

Degenerative disorders caused by Bcl-2 deficiency prevented by loss of its BH3-only antagonist Bim

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.3800750

7 January 2021

based on heuristic

inferred from DOI database lookup

Immunohistochemical expression of BCL-2 in melanomas and intradermal nevi

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.3800750

7 January 2021

based on heuristic

inferred from DOI database lookup

Intercellular adhesion molecule 1 (ICAM-1) and bcl-2 are differentially expressed in early evolving malignant melanoma.

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.3800750

7 January 2021

based on heuristic

inferred from DOI database lookup

bcl-2 protein expression in cutaneous malignant melanoma and benign melanocytic nevi.

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.3800750

7 January 2021

based on heuristic

inferred from DOI database lookup

Clinical and pathologic significance of activation of signal transducer and activator of transcription 3 in prostate cancer

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.3800750

7 January 2021

based on heuristic

inferred from DOI database lookup

Automated quantitative analysis of tissue microarrays reveals an association between high Bcl-2 expression and improved outcome in melanoma

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.3800750

7 January 2021

based on heuristic

inferred from DOI database lookup

Bcl-2 antisense (oblimersen sodium) plus dacarbazine in patients with advanced melanoma: the Oblimersen Melanoma Study Group

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.3800750

7 January 2021

based on heuristic

inferred from DOI database lookup

Bcl2 regulation by the melanocyte master regulator Mitf modulates lineage survival and melanoma cell viability

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.3800750

7 January 2021

based on heuristic

inferred from DOI database lookup

KIT receptor is expressed in more than 50% of early-stage malignant melanoma: a retrospective study of 261 patients

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.3800750

7 January 2021

based on heuristic

inferred from DOI database lookup

Regulation of gene expression in melanoma: new approaches for treatment

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.3800750

7 January 2021

based on heuristic

inferred from DOI database lookup

Downregulation of transcription factor AP-2 predicts poor survival in stage I cutaneous malignant melanoma.

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.3800750

7 January 2021

based on heuristic

inferred from DOI database lookup

Automated quantitative analysis of activator protein-2alpha subcellular expression in melanoma tissue microarrays correlates with survival prediction

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.3800750

7 January 2021

based on heuristic

inferred from DOI database lookup

Mcl-1 is overexpressed in multiple myeloma and associated with relapse and shorter survival.

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.3800750

7 January 2021

based on heuristic

inferred from DOI database lookup

Mcl-1 regulates survival and sensitivity to diverse apoptotic stimuli in human non-small cell lung cancer cells.

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.3800750

7 January 2021

based on heuristic

inferred from DOI database lookup

Overexpression of anti-apoptotic Mcl-1 in testicular germ cell tumours

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.3800750

7 January 2021

based on heuristic

inferred from DOI database lookup

Mcl-1 antisense therapy chemosensitizes human melanoma in a SCID mouse xenotransplantation model

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.3800750

7 January 2021

based on heuristic

inferred from DOI database lookup

Roles of activated Src and Stat3 signaling in melanoma tumor cell growth

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.3800750

7 January 2021

based on heuristic

inferred from DOI database lookup

Targeting Stat3 in cancer therapy

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.3800750

7 January 2021

based on heuristic

inferred from DOI database lookup

The role of Mcl-1 downregulation in the proapoptotic activity of the multikinase inhibitor BAY 43-9006.

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.3800750

7 January 2021

based on heuristic

inferred from DOI database lookup

Mule/ARF-BP1, a BH3-only E3 ubiquitin ligase, catalyzes the polyubiquitination of Mcl-1 and regulates apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.3800750

7 January 2021

based on heuristic

inferred from DOI database lookup

Role of nuclear factor-kappa B in melanoma

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.3800750

7 January 2021

based on heuristic

inferred from DOI database lookup

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