(Q80660182)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18259988%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

review article

1 reference

title

Structure-function analyses of single nucleotide polymorphisms in human N-acetyltransferase 1 (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18259988%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

3

David W Hein

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18259988%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

author name string

Jason M Walraven

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18259988%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

John O Trent

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18259988%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

publication date

1 January 2008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18259988%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

published in

Drug Metabolism Reviews

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18259988%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

volume

40

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18259988%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

page(s)

169-184

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18259988%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18259988%20AND%20SRC:MED&resulttype=core&format=json

UCSF Chimera--a visualization system for exploratory research and analysis

2 January 2020

cites work

1 reference

12 December 2020

Maternal smoking and the risk of orofacial clefts: Susceptibility with NAT1 and NAT2 polymorphisms

1 reference

12 December 2020

Proteasomal degradation of N-acetyltransferase 1 is prevented by acetylation of the active site cysteine: a mechanism for the slow acetylator phenotype and substrate-dependent down-regulation

1 reference

12 December 2020

Correlation between genotype and phenotype of the human arylamine N-acetyltransferase type 1 (NAT1).

1 reference

12 December 2020

Identification of amino acids imparting acceptor substrate selectivity to human arylamine acetyltransferases NAT1 and NAT2.

1 reference

12 December 2020

Structure of arylamine N-acetyltransferase reveals a catalytic triad

1 reference

12 December 2020

Characterization of naturally occurring and recombinant human N-acetyltransferase variants encoded by NAT1

1 reference

12 December 2020

Relevance of N-acetyltransferase 1 and 2 (NAT1, NAT2) genetic polymorphisms in non-small cell lung cancer susceptibility.

1 reference

12 December 2020

Eubacterial arylamine N-acetyltransferases - identification and comparison of 18 members of the protein family with conserved active site cysteine, histidine and aspartate residues

1 reference

12 December 2020

Functional characterization of nucleotide polymorphisms in the coding region of N-acetyltransferase 1.

1 reference

12 December 2020

Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications

1 reference

12 December 2020

3D model of human arylamine N-acetyltransferase 2: structural basis of the slow acetylator phenotype of the R64Q variant and analysis of the active-site loop.

1 reference

12 December 2020

Genetic polymorphisms in heterocyclic amine metabolism and risk of colorectal adenomas

1 reference

12 December 2020

The structure of arylamine N-acetyltransferase from Mycobacterium smegmatis--an enzyme which inactivates the anti-tubercular drug, isoniazid

1 reference

12 December 2020

Effect of nucleotide substitutions in N-acetyltransferase-1 on N-acetylation (deactivation) and O-acetylation (activation) of arylamine carcinogens: implications for cancer predisposition

1 reference

12 December 2020

Molecular genetics and function of NAT1 and NAT2: role in aromatic amine metabolism and carcinogenesis

1 reference

12 December 2020

Association of prostate cancer with rapid N-acetyltransferase 1 (NAT1*10) in combination with slow N-acetyltransferase 2 acetylator genotypes in a pilot case-control study

1 reference

12 December 2020

Permanent hair dyes and bladder cancer: risk modification by cytochrome P4501A2 and N-acetyltransferases 1 and 2.

1 reference

12 December 2020

N-acetyltransferase (NAT1, NAT2) and glutathione S-transferase (GSTM1, GSTT1) polymorphisms in breast cancer

1 reference

12 December 2020

Arylamine N-acetyltransferase-1 is highly expressed in breast cancers and conveys enhanced growth and resistance to etoposide in vitro.

1 reference

12 December 2020

Relationship between intratumoral expression of genes coding for xenobiotic-metabolizing enzymes and benefit from adjuvant tamoxifen in estrogen receptor alpha-positive postmenopausal breast carcinoma

1 reference

12 December 2020

Site-directed mutagenesis of recombinant human arylamine N-acetyltransferase expressed in Escherichia coli. Evidence for direct involvement of Cys68 in the catalytic mechanism of polymorphic human NAT2

1 reference

12 December 2020

Deletion of a xenobiotic metabolizing gene in mice affects folate metabolism.

1 reference

12 December 2020

Haplotype of N-acetyltransferase 1 and 2 and risk of pancreatic cancer

1 reference

12 December 2020

Functional effects of single nucleotide polymorphisms in the coding region of human N-acetyltransferase 1.

1 reference

12 December 2020

Satisfying hydrogen bonding potential in proteins

1 reference

12 December 2020

Polyadenylation polymorphism in the acetyltransferase 1 gene (NAT1) increases risk of colorectal cancer

1 reference

12 December 2020

Identification of a novel allele at the human NAT1 acetyltransferase locus

1 reference

12 December 2020

Identification and characterization of variant alleles of human acetyltransferase NAT1 with defective function using p-aminosalicylate as an in-vivo and in-vitro probe

1 reference

12 December 2020

Cigarette smoking, N-acetyltransferases 1 and 2, and breast cancer risk.

1 reference

12 December 2020

A prospective study of N-acetyltransferase genotype, red meat intake, and risk of colorectal cancer.

1 reference

12 December 2020

The role of N-acetylation polymorphisms in smoking-associated bladder cancer: evidence of a gene-gene-exposure three-way interaction.

1 reference

12 December 2020

N-acetyltransferase 1 genetic polymorphism, cigarette smoking, well-done meat intake, and breast cancer risk

1 reference

12 December 2020

Arylamine N-acetyltransferase 1 (NAT1) and 2 (NAT2) genes and risk of urothelial transitional cell carcinoma among Japanese

1 reference

12 December 2020

Periconceptional multivitamin intake during early pregnancy, genetic variation of acetyl-N-transferase 1 (NAT1), and risk for orofacial clefts

1 reference

12 December 2020

Eukaryotic arylamine N-acetyltransferase. Investigation of substrate specificity by high-throughput screening

1 reference

12 December 2020

Heterocyclic amines and genotype of N-acetyltransferases as risk factors for prostate cancer

1 reference

12 December 2020

Arylamine N-acetyltransferases: what we learn from genes and genomes

1 reference

12 December 2020

Polymorphisms of cytochrome P4501A2 and N-acetyltransferase genes, smoking, and risk of pancreatic cancer

1 reference

12 December 2020

Effect of NAT1 and NAT2 genetic polymorphisms on colorectal cancer risk associated with exposure to tobacco smoke and meat consumption

1 reference

12 December 2020

Loss of function polymorphisms in NAT1 protect against spina bifida

1 reference

12 December 2020

Genetic variation in N-acetyltransferase 1 (NAT1) and 2 (NAT2) and risk of non-Hodgkin lymphoma

1 reference

12 December 2020

Arylamine N-acetyltransferase aggregation and constitutive ubiquitylation.

1 reference

12 December 2020

N-Acetyltransferase-1 gene polymorphisms and correlation between genotype and its activity in a central Chinese Han population

1 reference

12 December 2020

Risk of limb deficiency defects associated with NAT1, NAT2, GSTT1, GSTM1, and NOS3 genetic variants, maternal smoking, and vitamin supplement intake

1 reference

12 December 2020

Insights into the o-acetylation reaction of hydroxylated heterocyclic amines by human arylamine N-acetyltransferases: a computational study

1 reference

12 December 2020

Computational and experimental analyses of mammalian arylamine N-acetyltransferase structure and function

1 reference

12 December 2020

Development of lung cancer before the age of 50: the role of xenobiotic metabolizing genes.

1 reference

12 December 2020

Hair dye use, meat intake, and tobacco exposure and presence of carcinogen-DNA adducts in exfoliated breast ductal epithelial cells

1 reference

12 December 2020

Hair dye use, genetic variation in N-acetyltransferase 1 (NAT1) and 2 (NAT2), and risk of non-Hodgkin lymphoma

1 reference

12 December 2020

Arylamine N-acetyltransferase I

1 reference

12 December 2020

Joint effects of the N-acetyltransferase 1 and 2 (NAT1 and NAT2) genes and smoking on bladder carcinogenesis: a literature-based systematic HuGE review and evidence synthesis

1 reference

12 December 2020

Arylamine N-acetyltransferases: characterization of the substrate specificities and molecular interactions of environmental arylamines with human NAT1 and NAT2

1 reference

12 December 2020

Structural basis of substrate-binding specificity of human arylamine N-acetyltransferases

1 reference

12 December 2020

10.1080/03602530701852917

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18259988%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18259988%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

1 reference