(Q90236625)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30010620%20AND%20SRC:MED&resulttype=core&format=json

12 April 2020

title

Antisense oligonucleotides extend survival and reverse decrement in muscle response in ALS models (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30010620%20AND%20SRC:MED&resulttype=core&format=json

amyotrophic lateral sclerosis

12 April 2020

main subject

1 reference

18

Merit Cudkowicz

1 reference

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12 April 2020

23

Timothy M Miller

1 reference

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12 April 2020

author name string

Alex McCampbell

1

1 reference

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12 April 2020

Tracy Cole

2

1 reference

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12 April 2020

Amy J Wegener

3

1 reference

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12 April 2020

Giulio S Tomassy

4

1 reference

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12 April 2020

Amy Setnicka

5

1 reference

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12 April 2020

Brandon J Farley

6

1 reference

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12 April 2020

Kathleen M Schoch

7

1 reference

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12 April 2020

Mariah L Hoye

8

1 reference

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12 April 2020

Mark Shabsovich

9

1 reference

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12 April 2020

Linhong Sun

10

1 reference

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12 April 2020

Yi Luo

11

1 reference

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12 April 2020

Mingdi Zhang

12

1 reference

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12 April 2020

Nicole Comfort

13

1 reference

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12 April 2020

Bin Wang

14

1 reference

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12 April 2020

Jessica Amacker

15

1 reference

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12 April 2020

Sai Thankamony

16

1 reference

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12 April 2020

David W Salzman

17

1 reference

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12 April 2020

Danielle L Graham

19

1 reference

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12 April 2020

C Frank Bennett

20

1 reference

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12 April 2020

Holly B Kordasiewicz

21

1 reference

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12 April 2020

Eric E Swayze

22

1 reference

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12 April 2020

publication date

16 July 2018

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30010620%20AND%20SRC:MED&resulttype=core&format=json

Journal of Clinical Investigation

12 April 2020

published in

1 reference

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12 April 2020

volume

128

1 reference

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12 April 2020

issue

8

1 reference

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12 April 2020

page(s)

3558-3567

1 reference

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Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation

12 April 2020

cites work

1 reference

12 December 2020

Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury

1 reference

12 December 2020

Mechanisms of selective motor neuron death in ALS: insights from transgenic mouse models of motor neuron disease

1 reference

12 December 2020

Phenotypic heterogeneity in motor neuron disease patients with CuZn-superoxide dismutase mutations in Scandinavia

1 reference

12 December 2020

Aggregation and Motor Neuron Toxicity of an ALS-Linked SOD1 Mutant Independent from Wild-Type SOD1

1 reference

12 December 2020

Variation in the biochemical/biophysical properties of mutant superoxide dismutase 1 enzymes and the rate of disease progression in familial amyotrophic lateral sclerosis kindreds.

1 reference

12 December 2020

Retrograde viral delivery of IGF-1 prolongs survival in a mouse ALS model.

1 reference

12 December 2020

Disease progression of human SOD1 (G93A) transgenic ALS model rats

1 reference

12 December 2020

Antisense oligonucleotide therapy for neurodegenerative disease.

1 reference

12 December 2020

Therapeutic effects of immunization with mutant superoxide dismutase in mice models of amyotrophic lateral sclerosis

1 reference

12 December 2020

An immunological epitope selective for pathological monomer-misfolded SOD1 in ALS.

1 reference

12 December 2020

Gene-targeted therapies for the central nervous system

1 reference

12 December 2020

Intracerebroventricular infusion of monoclonal antibody or its derived Fab fragment against misfolded forms of SOD1 mutant delays mortality in a mouse model of ALS

1 reference

12 December 2020

Wild-type and mutant SOD1 share an aberrant conformation and a common pathogenic pathway in ALS

1 reference

12 December 2020

Electrophysiological analysis of a murine model of motoneuron disease.

1 reference

12 December 2020

Absence of SOD1 leads to oxidative stress in peripheral nerve and causes a progressive distal motor axonopathy

1 reference

12 December 2020

Antisense-mediated exon inclusion

1 reference

12 December 2020

Sustained therapeutic reversal of Huntington's disease by transient repression of huntingtin synthesis.

1 reference

12 December 2020

Targeting of monomer/misfolded SOD1 as a therapeutic strategy for amyotrophic lateral sclerosis

1 reference

12 December 2020

Plasma neurofilament heavy chain levels correlate to markers of late stage disease progression and treatment response in SOD1(G93A) mice that model ALS

1 reference

12 December 2020

Pyrimethamine decreases levels of SOD1 in leukocytes and cerebrospinal fluid of ALS patients: a phase I pilot study

1 reference

12 December 2020

SOD1 in cerebral spinal fluid as a pharmacodynamic marker for antisense oligonucleotide therapy

1 reference

12 December 2020

An antisense oligonucleotide against SOD1 delivered intrathecally for patients with SOD1 familial amyotrophic lateral sclerosis: a phase 1, randomised, first-in-man study

1 reference

12 December 2020

Is SOD1 loss of function involved in amyotrophic lateral sclerosis?

1 reference

12 December 2020

Antisense reduction of tau in adult mice protects against seizures

1 reference

12 December 2020

Therapeutic AAV9-mediated suppression of mutant SOD1 slows disease progression and extends survival in models of inherited ALS

1 reference

12 December 2020

Targeting RNA foci in iPSC-derived motor neurons from ALS patients with a C9ORF72 repeat expansion

1 reference

12 December 2020

Targeted degradation of sense and antisense C9orf72 RNA foci as therapy for ALS and frontotemporal degeneration

1 reference

12 December 2020

Presymptomatic electrophysiological tests predict clinical onset and survival in SOD1(G93A) ALS mice

1 reference

12 December 2020

Delayed disease onset and extended survival in the SOD1G93A rat model of amyotrophic lateral sclerosis after suppression of mutant SOD1 in the motor cortex

1 reference

12 December 2020

Serial measurements of phosphorylated neurofilament-heavy in the serum of subjects with amyotrophic lateral sclerosis.

1 reference

12 December 2020

In vivo kinetic approach reveals slow SOD1 turnover in the CNS.

1 reference

12 December 2020

Neurofilaments in the diagnosis of motoneuron diseases: a prospective study on 455 patients

1 reference

12 December 2020

Adeno-associated virus-delivered artificial microRNA extends survival and delays paralysis in an amyotrophic lateral sclerosis mouse model

1 reference

12 December 2020

Gain of Toxicity from ALS/FTD-Linked Repeat Expansions in C9ORF72 Is Alleviated by Antisense Oligonucleotides Targeting GGGGCC-Containing RNAs

1 reference

12 December 2020

Increased 4R-Tau Induces Pathological Changes in a Human-Tau Mouse Model

1 reference

12 December 2020

Defining SOD1 ALS natural history to guide therapeutic clinical trial design

1 reference

12 December 2020

Oligodendrocytes contribute to motor neuron death in ALS via SOD1-dependent mechanism

1 reference

12 December 2020

Tau reduction prevents neuronal loss and reverses pathological tau deposition and seeding in mice with tauopathy.

1 reference

12 December 2020

Development of a simple, rapid, and robust intrathecal catheterization method in the rat.

1 reference

12 December 2020

Misfolded SOD1 is not a primary component of sporadic ALS.

1 reference

12 December 2020

MicroRNA Profiling Reveals Marker of Motor Neuron Disease in ALS Models.

1 reference

12 December 2020

Nusinersen versus Sham Control in Infantile-Onset Spinal Muscular Atrophy

1 reference

12 December 2020

Randomized, double-blind, placebo-controlled trial of arimoclomol in rapidly progressive SOD1 ALS.

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI99081

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30010620%20AND%20SRC:MED&resulttype=core&format=json

12 April 2020

1 reference

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12 April 2020

PubMed publication ID

30010620

1 reference