(Q90412545)

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Stereochemical and Mechanistic Investigation of the Reaction Catalyzed by Fom3 from Streptomyces fradiae, a Cobalamin-Dependent Radical S-Adenosylmethionine Methylase

scientific article published on 09 August 2018

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scholarly article

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Europe PubMed Central

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13 April 2020

Stereochemical and Mechanistic Investigation of the Reaction Catalyzed by Fom3 from Streptomyces fradiae, a Cobalamin-Dependent Radical S-Adenosylmethionine Methylase (English)

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13 April 2020

Streptomyces fradiae

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6

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author name string

Bo Wang

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13 April 2020

Anthony J Blaszczyk

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13 April 2020

Hayley L Knox

3

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13 April 2020

Shengbin Zhou

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13 April 2020

Elizabeth J Blaesi

5

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13 April 2020

Roy X Wang

7

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9 August 2018

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13 April 2020

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13

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full work available at URL

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19 March 2024

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4972-4984

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access restriction status

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Different biosynthetic pathways to fosfomycin in Pseudomonas syringae and Streptomyces species.

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Initial characterization of Fom3 from Streptomyces wedmorensis: The methyltransferase in fosfomycin biosynthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/30036047

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Spectroscopic and Electrochemical Characterization of the Iron–Sulfur and Cobalamin Cofactors of TsrM, an Unusual Radical S-Adenosylmethionine Methylase

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12 December 2020

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https://pubmed.ncbi.nlm.nih.gov/30036047

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1 reference

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1 reference

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inferred from PubMed ID database lookup

Efficient methylation of C2 in l-tryptophan by the cobalamin-dependent radical S-adenosylmethionine methylase TsrM requires an unmodified N1 amine.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30036047

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based on heuristic

inferred from PubMed ID database lookup

TsrM as a Model for Purifying and Characterizing Cobalamin-Dependent Radical S-Adenosylmethionine Methylases.

1 reference

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1 reference

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1 reference

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Stereochemical Course of Methyl Transfer by Cobalamin-Dependent Radical SAM Methyltransferase in Fosfomycin Biosynthesis

1 reference

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C-Methylation Catalyzed by Fom3, a Cobalamin-Dependent Radical S-adenosyl-l-methionine Enzyme in Fosfomycin Biosynthesis, Proceeds with Inversion of Configuration

1 reference

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1 reference

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Biochemical and Structural Analysis of FomD That Catalyzes the Hydrolysis of Cytidylyl ( S)-2-Hydroxypropylphosphonate in Fosfomycin Biosynthesis

1 reference

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Identifiers

10.1021/ACS.BIOCHEM.8B00693

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13 April 2020

1 reference

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13 April 2020

1 reference

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13 April 2020

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