(Q919787)

English

Interleukin 15

mammalian protein found in Homo sapiens

uniprot:P40933
interleukin-15
IL15

In more languages

Statements

1 reference

13 November 2019

UniProt protein ID

Interleukin-15, mammal

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P40933

four-helical cytokine-like, core

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P40933

Protein IL15 PDB 2Z3Q.png
936 × 719; 74 KB

0 references

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

protein binding

determination method

3 references

8 April 2019

A proteome-scale map of the human interactome network

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40933

determination method

8 April 2019

Soluble interleukin-15 receptor alpha (IL-15R alpha)-sushi as a selective and potent agonist of IL-15 action through IL-15R beta/gamma. Hyperagonist IL-15 x IL-15R alpha fusion proteins

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40933

determination method

8 April 2019

Mechanistic and structural insight into the functional dichotomy between IL-2 and IL-15

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40933

determination method

cytokine receptor binding

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40933

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40933

determination method

integral component of plasma membrane

determination method

1 reference

31 October 2017

Altered natural killer cell differentiation in CD34+ progenitors from chronic myeloid leukemia patients

http://www.ebi.ac.uk/QuickGO/annotations?protein=P40933&geneProductId=UniProtKB:P40933

determination method

Golgi apparatus

determination method

1 reference

8 April 2019

Altered natural killer cell differentiation in CD34+ progenitors from chronic myeloid leukemia patients

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40933

determination method

determination method

1 reference

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40933

determination method

determination method

1 reference

31 October 2017

Altered natural killer cell differentiation in CD34+ progenitors from chronic myeloid leukemia patients

http://www.ebi.ac.uk/QuickGO/annotations?protein=P40933&geneProductId=UniProtKB:P40933

determination method

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40933

determination method

extracellular region

determination method

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40933

determination method

8 April 2019

The human plasma proteome: a nonredundant list developed by combination of four separate sources

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40933

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40933

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40933

determination method

extracellular space

determination method

3 references

8 April 2019

Altered natural killer cell differentiation in CD34+ progenitors from chronic myeloid leukemia patients

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40933

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40933

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40933

determination method

determination method

3 references

8 April 2019

Altered natural killer cell differentiation in CD34+ progenitors from chronic myeloid leukemia patients

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40933

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40933

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40933

determination method

determination method

1 reference

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40933

determination method

determination method

1 reference

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40933

determination method

biological process

negative regulation of smooth muscle cell proliferation

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40933

determination method

cell maturation

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40933

determination method

extrathymic T cell selection

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40933

determination method

positive regulation of T cell proliferation

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40933

determination method

regulation of defense response to virus by host

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40933

determination method

positive regulation of inflammatory response

determination method

1 reference

8 April 2019

Divergent effects of IL-12 and IL-23 on the production of IL-17 by human T cells

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40933

determination method

response to nutrient levels

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40933

determination method

positive regulation of protein O-linked glycosylation

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40933

determination method

positive regulation of interleukin-17 production

determination method

1 reference

8 April 2019

Divergent effects of IL-12 and IL-23 on the production of IL-17 by human T cells

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40933

determination method

hyaluronan metabolic process

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40933

determination method

positive regulation of natural killer cell differentiation

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40933

determination method

regulation of T cell differentiation

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40933

determination method

positive regulation of tissue remodeling

determination method

1 reference

8 April 2019

Divergent effects of IL-12 and IL-23 on the production of IL-17 by human T cells

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40933

determination method

cellular response to vitamin D

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40933

determination method

lymph node development

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40933

determination method

natural killer cell differentiation

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40933

determination method

positive regulation of natural killer cell proliferation

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40933

determination method

cell-cell signaling

determination method

1 reference

8 April 2019

Chromosomal assignment and genomic structure of Il15

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40933

determination method

skeletal muscle atrophy

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40933

determination method

signal transduction

determination method

1 reference

8 April 2019

Cloning of a T cell growth factor that interacts with the beta chain of the interleukin-2 receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40933

determination method

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40933

determination method

NK T cell proliferation

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40933

determination method

positive regulation of immune response

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40933

determination method

inflammatory response

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40933

determination method

tyrosine phosphorylation of STAT protein

determination method

1 reference

8 April 2019

IL-21 up-regulates the expression of genes associated with innate immunity and Th1 response

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40933

determination method

positive regulation of tyrosine phosphorylation of STAT protein

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40933

determination method

regulation of signaling receptor activity

determination method

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40933

determination method

interleukin-15-mediated signaling pathway

determination method

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40933

determination method

8 April 2019

Interleukin-15 enhances human neutrophil phagocytosis by a Syk-dependent mechanism: importance of the IL-15Ralpha chain

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40933

determination method

8 April 2019

CD4 ligation on human blood monocytes triggers macrophage differentiation and enhances HIV infection

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40933

determination method

neutrophil activation

determination method

1 reference

8 April 2019

Interleukin-15 enhances human neutrophil phagocytosis by a Syk-dependent mechanism: importance of the IL-15Ralpha chain

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40933

determination method

positive regulation of peptidyl-tyrosine phosphorylation

determination method

1 reference

8 April 2019

Interleukin-15 enhances human neutrophil phagocytosis by a Syk-dependent mechanism: importance of the IL-15Ralpha chain

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40933

determination method

positive regulation of phagocytosis

determination method

1 reference

8 April 2019

Interleukin-15 enhances human neutrophil phagocytosis by a Syk-dependent mechanism: importance of the IL-15Ralpha chain

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40933

determination method

macrophage differentiation

determination method

1 reference

8 April 2019

CD4 ligation on human blood monocytes triggers macrophage differentiation and enhances HIV infection

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40933

determination method

Gene Atlas image

PBB GE IL15 205992 s at fs.png
732 × 530; 11 KB

0 references

Identifiers

MeSH descriptor ID

0 references

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000296545

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000296545

ENSP00000323505

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000323505

ENSP00000377714

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000377714

ENSP00000422271

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000422271

ENSP00000435462

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000435462

ENSP00000436914

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000436914

1 reference

Freebase Data Dumps

publication date

28 October 2013

PDB structure ID

1 reference

UniProt protein ID

29 June 2016

language of work or name

1 reference

UniProt protein ID

29 June 2016

language of work or name

1 reference

UniProt protein ID

29 June 2016

language of work or name

1 reference

UniProt protein ID

29 June 2016

language of work or name

1 reference

based on heuristic

inferred by common MeSH mappings on source and on Wikidata

25 May 2023

Sitelinks

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Wikisource(0 entries)

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Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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