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SARS-CoV-2 and COVID-19: is interleukin-6 (IL-6) the 'culprit lesion' of ARDS onset? What is there besides Tocilizumab? SGP130Fc
scientific article published on 14 May 2020
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Europe PubMed Central
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7224649
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32421092%20AND%20SRC:MED&resulttype=core&format=json
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24 May 2020
title
SARS-CoV-2 and COVID-19: is interleukin-6 (IL-6) the 'culprit lesion' of ARDS onset? What is there besides Tocilizumab? SGP130Fc
(English)
1 reference
stated in
Europe PubMed Central
PMCID
7224649
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32421092%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 May 2020
main subject
SARS-CoV-2
1 reference
based on heuristic
inferred from title
COVID-19
1 reference
based on heuristic
inferred from title
tocilizumab
1 reference
based on heuristic
inferred from title
author name string
Giuseppe Magro
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
7224649
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32421092%20AND%20SRC:MED&resulttype=core&format=json
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24 May 2020
publication date
14 May 2020
1 reference
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Europe PubMed Central
PMCID
7224649
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32421092%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 May 2020
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100029
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Europe PubMed Central
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7224649
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32421092%20AND%20SRC:MED&resulttype=core&format=json
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24 May 2020
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10 February 2021
Effect of IL-6 deficiency on susceptibility to HSV-1 respiratory infection and intrinsic macrophage antiviral resistance
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7224649
retrieved
10 February 2021
Mouse-passaged severe acute respiratory syndrome-associated coronavirus leads to lethal pulmonary edema and diffuse alveolar damage in adult but not young mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7224649
retrieved
10 February 2021
Identification of oxidative stress and Toll-like receptor 4 signaling as a key pathway of acute lung injury
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7224649
retrieved
10 February 2021
Interleukin-6 is crucial for recall of influenza-specific memory CD4 T cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7224649
retrieved
10 February 2021
Transgenic blockade of interleukin 6 transsignaling abrogates inflammation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7224649
retrieved
10 February 2021
Nucleocapsid protein of SARS-CoV activates interleukin-6 expression through cellular transcription factor NF-kappaB.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7224649
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10 February 2021
The IL-6/sIL-6R complex as a novel target for therapeutic approaches
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7224649
retrieved
10 February 2021
A novel TLR4-mediated signaling pathway leading to IL-6 responses in human bladder epithelial cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7224649
retrieved
10 February 2021
Manipulation of the nuclear factor-kappaB pathway and the innate immune response by viruses
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7224649
retrieved
10 February 2021
IRFs: master regulators of signalling by Toll-like receptors and cytosolic pattern-recognition receptors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7224649
retrieved
10 February 2021
Differential expression of CD126 and CD130 mediates different STAT-3 phosphorylation in CD4+CD25- and CD25high regulatory T cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7224649
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10 February 2021
Cytokine regulation in SARS coronavirus infection compared to other respiratory virus infections
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7224649
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10 February 2021
Heritable defects of the human TLR signalling pathways
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stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7224649
retrieved
10 February 2021
The IL-6R alpha chain controls lung CD4+CD25+ Treg development and function during allergic airway inflammation in vivo.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7224649
retrieved
10 February 2021
Temporal relationship of viral load, ribavirin, interleukin (IL)-6, IL-8, and clinical progression in patients with severe acute respiratory syndrome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7224649
retrieved
10 February 2021
Patient data, early SARS epidemic, Taiwan
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7224649
retrieved
10 February 2021
Principles of interleukin (IL)-6-type cytokine signalling and its regulation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7224649
retrieved
10 February 2021
Generation and function of the soluble interleukin-6 receptor.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7224649
retrieved
10 February 2021
Role of IL-6 and its soluble receptor in induction of chemokines and leukocyte recruitment.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7224649
retrieved
10 February 2021
Serum interleukin-6 (IL-6) and interleukin-4 (IL-4) in patients with multiple myeloma (MM)
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7224649
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10 February 2021
Detection of membrane and soluble interleukin-6 receptor in lymphoid malignancies
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7224649
retrieved
10 February 2021
Soluble receptors for cytokines and growth factors: generation and biological function
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7224649
retrieved
10 February 2021
Studies on the structure and regulation of the human hepatic interleukin-6 receptor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7224649
retrieved
10 February 2021
Isolation of an mRNA encoding a soluble form of the human interleukin-6 receptor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7224649
retrieved
10 February 2021
Identifiers
DOI
10.1016/J.CYTOX.2020.100029
1 reference
stated in
Europe PubMed Central
PMCID
7224649
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32421092%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 May 2020
COVIDWHO ID
covidwho-260088
0 references
Dimensions Publication ID
1127619516
1 reference
stated in
Dimensions COVID-19 publications, datasets and clinical trials
DOI
10.6084/M9.FIGSHARE.11961063
retrieved
28 May 2020
PMCID
7224649
1 reference
stated in
Europe PubMed Central
PMCID
7224649
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32421092%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 May 2020
PubMed ID
32421092
1 reference
stated in
Europe PubMed Central
PMCID
7224649
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32421092%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 May 2020
Semantic Scholar corpus ID
218631917
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