Wikidata:Property proposal/phosphorylates
can phosphorylate edit
Originally proposed at Wikidata:Property proposal/Natural science
Not done
| Description | Property of kinase proteins to add phosphate to target substrate proteins. |
|---|---|
| Represents | protein phosphorylation (Q7251493)) |
| Data type | Item |
| Domain | instances of protein (Q8054) |
| Allowed values | instances of protein (Q8054) |
| Example 1 | CAMK1 (Q18033081) → CAMP responsive element binding protein 1 (Q21116771) Ref: UniProt |
| Example 2 | CAMK1 (Q18033081) → Eukaryotic translation initiation factor 4 gamma 3 (Q21108761) Ref: UniProt |
| Example 3 | Cyclin dependent kinase 2 (Q511968) → RB transcriptional corepressor 1 (Q21111463) Ref: ṔMC49822 |
| Example 4 | mitogen-activated protein kinase kinase kinase 1 (Q21170755) → mitogen-activated protein kinase kinase 7 (Q21109744) Ref Reactome |
| Source | Many databases available with different degrees of curation. Examples include data reported in UniProt, phosphonetworks and X2K. |
| Planned use | Manually assign major biological relations of kinases and their targets. Sift throught the literature to find reliable sources for future migration to wikidata. |
Motivation edit
Protein phosphorylation is central to biological signal transduction. Basic cell biology in undergraduate textbook includes diverse protein phosphorylation cascades. Modelling this property allow us to bring knowledge regarding kinases and their targets to wikidata. This can be done both manually, citing the scientific literature, or in batches using curated databases.
TiagoLubiana (talk) 04:48, 15 June 2019 (UTC)
Discussion edit
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