Wikidata:Requests for comment/Adding URL reference to claims using pywikibot

An editor has requested the community to provide input on "Adding URL reference to claims using pywikibot" via the Requests for comment (RFC) process. This is the discussion page regarding the issue.

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I'm having trouble understanding the details of claims as references in the pywikibot API reference. I'm trying to add a URL reference to a claim I'd like to add to a list of items, however it doesn't seem as straightforward as it is in the graphical web editor to me. I can't find examples online and using search engines gives any result mentioning the API reference. Is this not a best practice? Is there a reason for so few mentions of how to do this?