(Q24292698)

GOA release 2020-03-11

cellular senescence

1 reference

GOA release 2020-03-11

author

Zbyszek Darzynkiewicz

object named as

Zbigniew Darzynkiewicz

8

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author name string

Jun Chen

1

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Xuan Huang

2

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Dorota Halicka

3

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Sergey Brodsky

4

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Ari Avram

5

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Jonathan Eskander

6

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Noah A Bloomgarden

7

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Michael S Goligorsky

American Journal of Physiology Heart and Circulatory Physiology

9

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language of work or name

English

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publication date

April 2006

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published in

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volume

290

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page(s)

H1575-86

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issue

4

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cites work

Assessment of histone H2AX phosphorylation induced by DNA topoisomerase I and II inhibitors topotecan and mitoxantrone and by the DNA cross-linking agent cisplatin

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7 January 2021

The role of oxidative stress in the onset and progression of diabetes and its complications: a summary of a Congress Series sponsored by UNESCO-MCBN, the American Diabetes Association and the German Diabetes Society

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https://api.crossref.org/works/10.1152%2FAJPHEART.00364.2005

7 January 2021

Advanced glycosylation end products: a new disease marker for diabetes and aging

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https://api.crossref.org/works/10.1152%2FAJPHEART.00364.2005

7 January 2021

Functional reassessment of P16 variants using a transfection-based assay

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https://api.crossref.org/works/10.1152%2FAJPHEART.00364.2005

7 January 2021

Differentiation between senescence (M1) and crisis (M2) in human fibroblast cultures

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https://api.crossref.org/works/10.1152%2FAJPHEART.00364.2005

7 January 2021

p107 and p130: versatile proteins with interesting pockets

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00364.2005

7 January 2021

Phenotypic alterations in senescent large-vessel and microvascular endothelial cells

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00364.2005

7 January 2021

Telomerase and human tumorigenesis

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00364.2005

7 January 2021

The serial cultivation of human diploid cell strains

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00364.2005

7 January 2021

The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00364.2005

7 January 2021

Insights on immunological aging derived from the T lymphocyte cellular senescence model

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00364.2005

7 January 2021

Senescence-associated cell death of human endothelial cells: the role of oxidative stress

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00364.2005

7 January 2021

Direct evidence from siRNA-directed "knock down" that p16(INK4a) is required for human fibroblast senescence and for limiting ras-induced epithelial cell proliferation

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00364.2005

7 January 2021

Histone deacetylase inhibitors induce a senescence-like state in human cells by a p16-dependent mechanism that is independent of a mitotic clock

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00364.2005

7 January 2021

Telomere shortening and cellular senescence in a model of chronic renal allograft rejection

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00364.2005

7 January 2021

Mutant p53 can delay growth arrest and loss of CDK2 activity in senescing human fibroblasts without reducing p21WAF1 expression

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00364.2005

7 January 2021

Enhanced apoptosis in prolonged cultures of senescent porcine pulmonary artery endothelial cells

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https://api.crossref.org/works/10.1152%2FAJPHEART.00364.2005

7 January 2021

p53, the cellular gatekeeper for growth and division

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00364.2005

7 January 2021

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00364.2005

7 January 2021

A senescence program controlled by p53 and p16INK4a contributes to the outcome of cancer therapy

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https://api.crossref.org/works/10.1152%2FAJPHEART.00364.2005

7 January 2021

The retinoblastoma gene family: cousins with overlapping interests.

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https://api.crossref.org/works/10.1152%2FAJPHEART.00364.2005

7 January 2021

The p16INK4a/CDKN2A tumor suppressor and its relatives.

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00364.2005

7 January 2021

Tumor suppressors and oncogenes in cellular senescence.

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00364.2005

7 January 2021

Cellular and molecular mechanisms of stress-induced premature senescence (SIPS) of human diploid fibroblasts and melanocytes

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00364.2005

7 January 2021

Replicative senescence of human endothelial cells in vitro involves G1 arrest, polyploidization and senescence-associated apoptosis

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00364.2005

7 January 2021

The role of AGEs in aging: causation or correlation

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00364.2005

7 January 2021

The INK4A/ARF locus and its two gene products

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00364.2005

7 January 2021

Inhibitors of cyclin-dependent kinases induce features of replicative senescence in early passage human diploid fibroblasts

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00364.2005

7 January 2021

The tumor-suppressive functions of the human INK4A locus

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00364.2005

7 January 2021

Tumor suppressor p16INK4a determines sensitivity of human cells to transformation by cooperating cellular oncogenes

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00364.2005

7 January 2021

Suppression of accelerated diabetic atherosclerosis by the soluble receptor for advanced glycation endproducts

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00364.2005

7 January 2021

A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00364.2005

7 January 2021

Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00364.2005

7 January 2021

Telomere states and cell fates

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00364.2005

7 January 2021

A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00364.2005

7 January 2021

Biochemistry and molecular cell biology of diabetic complications

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00364.2005

7 January 2021

The retinoblastoma tumour suppressor in development and cancer

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00364.2005

7 January 2021

Loss of retinoblastoma but not p16 function allows bypass of replicative senescence in human fibroblasts

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00364.2005

7 January 2021

Telomeres, aging and cancer: in search of a happy ending

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00364.2005

7 January 2021

Sequential extension of proliferative lifespan in human fibroblasts induced by over-expression of CDK4 or 6 and loss of p53 function.

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00364.2005

7 January 2021

Hallmarks of senescence in carcinogenesis and cancer therapy

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00364.2005

7 January 2021

Advanced glycation end products, oxidant stress and vascular lesions

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00364.2005

7 January 2021

Advanced glycosylation end products in tissue and the biochemical basis of diabetic complications

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00364.2005

7 January 2021

Retinopathy and nephropathy in patients with type 1 diabetes four years after a trial of intensive therapy

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00364.2005

7 January 2021

Aminoguanidine treatment inhibits the development of experimental diabetic retinopathy

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00364.2005

7 January 2021

Senescence-like growth arrest induced by hydrogen peroxide in human diploid fibroblast F65 cells.

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00364.2005

7 January 2021

Advanced glycation end products (AGEs) on the surface of diabetic erythrocytes bind to the vessel wall via a specific receptor inducing oxidant stress in the vasculature: a link between surface-associated AGEs and diabetic complications

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00364.2005

7 January 2021

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00364.2005

7 January 2021

Activation of the receptor for advanced glycation end products triggers a p21(ras)-dependent mitogen-activated protein kinase pathway regulated by oxidant stress.

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00364.2005

7 January 2021

Reversal of senescence in mouse fibroblasts through lentiviral suppression of p53.

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00364.2005

7 January 2021

p21-dependent inhibition of colon cancer cell growth by mevastatin is independent of inhibition of G1 cyclin-dependent kinases

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00364.2005

7 January 2021

The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2.

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00364.2005

7 January 2021

INK4a-deficient human diploid fibroblasts are resistant to RAS-induced senescence

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00364.2005

7 January 2021

Reversal of human cellular senescence: roles of the p53 and p16 pathways

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00364.2005

7 January 2021

pRB and p107/p130 are required for the regulated expression of different sets of E2F responsive genes.

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00364.2005

7 January 2021

CDK inhibitors: positive and negative regulators of G1-phase progression

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00364.2005

7 January 2021

Replicative senescence and oxidant-induced premature senescence. Beyond the control of cell cycle checkpoints

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00364.2005

7 January 2021

A system for stable expression of short interfering RNAs in mammalian cells

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00364.2005

7 January 2021

Bypass of senescence after disruption of p21CIP1/WAF1 gene in normal diploid human fibroblasts

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00364.2005

7 January 2021

Reinitiation of DNA synthesis and cell division in senescent human fibroblasts by microinjection of anti-p53 antibodies

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00364.2005

7 January 2021

Induction of p21(WAF1/CIP1) and inhibition of Cdk2 mediated by the tumor suppressor p16(INK4a)

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00364.2005

7 January 2021

Control of the replicative life span of human fibroblasts by p16 and the polycomb protein Bmi-1

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00364.2005

7 January 2021

Delayed branching of endothelial capillary-like cords in glycated collagen I is mediated by early induction of PAI-1

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00364.2005

7 January 2021

Endothelial cell senescence in human atherosclerosis: role of telomere in endothelial dysfunction

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00364.2005

7 January 2021

Glycated collagen I induces premature senescence-like phenotypic changes in endothelial cells

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00364.2005

7 January 2021

Senescence and death of primitive cells and myocytes lead to premature cardiac aging and heart failure

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00364.2005

7 January 2021

Prevention and reversal of premature endothelial cell senescence and vasculopathy in obesity-induced diabetes by ebselen

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00364.2005

7 January 2021

Activation of receptor for advanced glycation end products: a mechanism for chronic vascular dysfunction in diabetic vasculopathy and atherosclerosis

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00364.2005

7 January 2021

Receptor-mediated endothelial cell dysfunction in diabetic vasculopathy. Soluble receptor for advanced glycation end products blocks hyperpermeability in diabetic rats

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00364.2005

7 January 2021

Immunohistochemical colocalization of glycoxidation products and lipid peroxidation products in diabetic renal glomerular lesions. Implication for glycoxidative stress in the pathogenesis of diabetic nephropathy

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00364.2005

7 January 2021

Progression of incipient diabetic retinopathy during good glycemic control.

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00364.2005

7 January 2021

Progression of nephropathy in spontaneous diabetic rats is prevented by OPB-9195, a novel inhibitor of advanced glycation

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00364.2005

7 January 2021

Hyperhomocyst(e)inemia and endothelial dysfunction in IDDM.

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00364.2005

7 January 2021