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Holding their own: the noncanonical roles of Smad proteins
scientific article
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instance of
scholarly article
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review article
1 reference
stated in
Europe PubMed Central
title
Holding their own: the noncanonical roles of Smad proteins
(English)
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main subject
SMAD family member 3
1 reference
stated in
GOA release 2020-03-11
TTK protein kinase
1 reference
stated in
GOA release 2020-03-11
SMAD family member 5
1 reference
stated in
GOA release 2020-03-11
SMAD family member 7
1 reference
stated in
GOA release 2020-03-11
SMAD family member 9
1 reference
stated in
GOA release 2020-03-11
SMAD family member 1
1 reference
stated in
GOA release 2020-03-11
SMAD family member 6
1 reference
stated in
GOA release 2020-03-11
SMAD family member 2
1 reference
stated in
GOA release 2020-03-11
transforming growth factor beta 1
1 reference
stated in
GOA release 2020-03-11
BMP signaling pathway
1 reference
stated in
GOA release 2020-03-11
author name string
Loretta L Hoover
series ordinal
1
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Steven W Kubalak
series ordinal
2
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language of work or name
English
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publication date
2008
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published in
Science Signaling
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volume
1
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page(s)
pe48
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issue
46
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cites work
Smad7 induces hepatic metastasis in colorectal cancer
1 reference
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PubMed Central
reference URL
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19 March 2017
Smad7 stabilizes beta-catenin binding to E-cadherin complex and promotes cell-cell adhesion
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PubMed Central
reference URL
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19 March 2017
TGF-beta signal transduction
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913314
retrieved
19 March 2017
SMAD proteins control DROSHA-mediated microRNA maturation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913314
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19 March 2017
Programmed cell death 4 (PDCD4) is an important functional target of the microRNA miR-21 in breast cancer cells
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913314
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19 March 2017
Identification of novel Smad binding proteins
1 reference
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PubMed Central
reference URL
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19 March 2017
Regulation of transforming growth factor-beta signaling by protein inhibitor of activated STAT, PIASy through Smad3
1 reference
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PubMed Central
reference URL
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19 March 2017
TGF-beta signalling from cell membrane to nucleus through SMAD proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913314
retrieved
19 March 2017
MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913314
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7 April 2017
Specificity and versatility in tgf-beta signaling through Smads
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913314
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7 April 2017
Retinoids regulate TGFbeta signaling at the level of Smad2 phosphorylation and nuclear accumulation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913314
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27 September 2017
MicroRNA-21 targets tumor suppressor genes in invasion and metastasis
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PubMed Central
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27 September 2017
On the role of transforming growth factor-beta in the growth inhibitory effects of retinoic acid in human pancreatic cancer cells
1 reference
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PubMed Central
reference URL
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27 September 2017
Activation of Mps1 promotes transforming growth factor-beta-independent Smad signaling.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913314
retrieved
27 September 2017
Effect of Smad7 expression on metastasis of mouse mammary carcinoma JygMC(A) cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913314
retrieved
27 September 2017
Kinetic analysis of Smad nucleocytoplasmic shuttling reveals a mechanism for transforming growth factor beta-dependent nuclear accumulation of Smads
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913314
retrieved
27 September 2017
Stable overexpression of Smad7 in human melanoma cells inhibits their tumorigenicity in vitro and in vivo
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913314
retrieved
27 September 2017
Smad7 induces tumorigenicity by blocking TGF-beta-induced growth inhibition and apoptosis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913314
retrieved
27 September 2017
Fine tuning and cross-talking of TGF-beta signal by inhibitory Smads
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913314
retrieved
27 September 2017
TGF-beta and the Smad signaling pathway support transcriptomic reprogramming during epithelial-mesenchymal cell transition
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913314
retrieved
27 September 2017
Integration of the TGF-beta pathway into the cellular signalling network
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913314
retrieved
27 September 2017
Smads as transcriptional co-modulators
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913314
retrieved
27 September 2017
Functions of mammalian Smad genes as revealed by targeted gene disruption in mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913314
retrieved
27 September 2017
Microtubule binding to Smads may regulate TGF beta activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913314
retrieved
27 September 2017
Smad2 transduces common signals from receptor serine-threonine and tyrosine kinases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913314
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27 September 2017
The TGF-beta superfamily: new members, new receptors, and new genetic tests of function in different organisms
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913314
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27 September 2017
New class of transforming growth factors potentiated by epidermal growth factor: isolation from non-neoplastic tissues
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913314
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27 September 2017
TGF-beta and retinoic acid: regulators of growth and modifiers of differentiation in human epidermal cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913314
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27 September 2017
Smad7 but not Smad6 cooperates with oncogenic ras to cause malignant conversion in a mouse model for squamous cell carcinoma.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913314
retrieved
30 May 2018
Cell type-specific modulation of cell growth by transforming growth factor beta 1 does not correlate with mitogen-activated protein kinase activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913314
retrieved
30 May 2018
Stable Overexpression of Smad7 in Human Melanoma Cells Impairs Bone Metastasis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913314
retrieved
29 November 2018
All-trans retinoic acid inhibited chondrogenesis of mouse embryonic palate mesenchymal cells by down-regulation of TGF-beta/Smad signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913314
retrieved
29 November 2018
Transforming growth factor-beta regulates growth as well as collagen and fibronectin synthesis of human marrow fibroblasts
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19018011
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Interactions between retinoids and TGF beta s in mouse morphogenesis
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19018011
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1126/SCISIGNAL.146PE48
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PMCID
2913314
0 references
PubMed ID
19018011
0 references
ResearchGate publication ID
23482236
0 references
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