(Q24336344)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19965867%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

title

Modulation of retinoic acid receptor-related orphan receptor alpha and gamma activity by 7-oxygenated sterol ligands (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19965867%20AND%20SRC:MED&resulttype=core&format=json

RAR related orphan receptor A

13 February 2020

main subject

cell biology

0 references

1 reference

RAR related orphan receptor C

1 reference

ligand-activated transcription factor activity

1 reference

RAR-related orphan receptor gamma

1 reference

RAR-related orphan receptor alpha

1 reference

1 reference

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19965867%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Thomas Burris

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19965867%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

author name string

Yongjun Wang

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19965867%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Naresh Kumar

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19965867%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Laura A Solt

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19965867%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Timothy I Richardson

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19965867%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Leah M Helvering

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19965867%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Christine Crumbley

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19965867%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Ruben D Garcia-Ordonez

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19965867%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Keith R Stayrook

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19965867%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Scott Novick

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19965867%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Michael J Chalmers

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19965867%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Patrick R Griffin

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19965867%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

language of work or name

English

0 references

publication date

4 December 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19965867%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

13 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19965867%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

volume

285

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19965867%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

issue

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19965867%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

page(s)

5013-5025

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19965867%20AND%20SRC:MED&resulttype=core&format=json

REV-ERBalpha participates in circadian SREBP signaling and bile acid homeostasis

13 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836105

Bile acids: regulation of synthesis

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836105

Identification of heme as the ligand for the orphan nuclear receptors REV-ERBalpha and REV-ERBbeta

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836105

Rev-erbalpha, a heme sensor that coordinates metabolic and circadian pathways

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836105

Transcriptional regulation of apolipoprotein C-III gene expression by the orphan nuclear receptor RORalpha

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836105

Structural requirements of ligands for the oxysterol liver X receptors LXRalpha and LXRbeta

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836105

Disruption of retinoid-related orphan receptor beta changes circadian behavior, causes retinal degeneration and leads to vacillans phenotype in mice

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836105

RZRs, a new family of retinoid-related orphan receptors that function as both monomers and homodimers

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836105

Isoform-specific amino-terminal domains dictate DNA-binding properties of ROR alpha, a novel family of orphan hormone nuclear receptors

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836105

ROR gamma: the third member of ROR/RZR orphan receptor subfamily that is highly expressed in skeletal muscle

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836105

Structural basis for the activation of PPARgamma by oxidized fatty acids

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836105

Partial agonists activate PPARgamma using a helix 12 independent mechanism

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836105

Crystal structure of the human RORalpha Ligand binding domain in complex with cholesterol sulfate at 2.2 A

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836105

All-trans retinoic acid is a ligand for the orphan nuclear receptor ROR beta

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836105

X-ray structure of the hRORalpha LBD at 1.63 A: structural and functional data that cholesterol or a cholesterol derivative is the natural ligand of RORalpha

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836105

T helper 17 lineage differentiation is programmed by orphan nuclear receptors ROR alpha and ROR gamma

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836105

Differential control of Bmal1 circadian transcription by REV-ERB and ROR nuclear receptors

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836105

The orphan nuclear receptor RORalpha regulates circadian transcription of the mammalian core-clock Bmal1

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836105

The enzymes, regulation, and genetics of bile acid synthesis

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836105

The orphan nuclear receptor REV-ERBalpha controls circadian transcription within the positive limb of the mammalian circadian oscillator

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836105

Cloning of a cDNA encoding the murine orphan receptor RZR/ROR gamma and characterization of its response element

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836105

Absence of the SRC-2 coactivator results in a glycogenopathy resembling Von Gierke's disease

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836105

Regulation of bile acid synthesis by the nuclear receptor Rev-erbalpha

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836105

Identification of oxysterol 7alpha-hydroxylase (Cyp7b1) as a novel retinoid-related orphan receptor alpha (RORalpha) (NR1F1) target gene and a functional cross-talk between RORalpha and liver X receptor (NR1H3)

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836105

Gene expression profiling reveals a regulatory role for ROR alpha and ROR gamma in phase I and phase II metabolism

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836105

A novel isoform of the orphan nuclear receptor RORbeta is specifically expressed in pineal gland and retina

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836105

A functional genomics strategy reveals Rora as a component of the mammalian circadian clock

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836105

HD desktop: an integrated platform for the analysis and visualization of H/D exchange data

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836105

Fifty years of advances in bile acid synthesis and metabolism

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836105

7-oxysterols modulate glucocorticoid activity in adipocytes through competition for 11beta-hydroxysteroid dehydrogenase type.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836105

Nuclear hormone receptors for heme: REV-ERBalpha and REV-ERBbeta are ligand-regulated components of the mammalian clock.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836105

Bile acid sequestrants and the treatment of type 2 diabetes mellitus

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836105

Enzymatic reduction of oxysterols impairs LXR signaling in cultured cells and the livers of mice.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836105

Probing protein ligand interactions by automated hydrogen/deuterium exchange mass spectrometry

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836105

Novel routes for metabolism of 7-ketocholesterol

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836105

Regulation of bile acid synthesis: pathways, nuclear receptors, and mechanisms.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836105

Identification of natural ligands of retinoic acid receptor-related orphan receptor α ligand-binding domain expressed in Sf9 cells––a mass spectrometry approach

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836105

Sterols in microorganisms

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836105

staggerer phenotype in retinoid-related orphan receptor alpha-deficient mice.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836105

Transcriptional regulation of apolipoprotein A-I gene expression by the nuclear receptor RORalpha

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836105

Disruption of the nuclear hormone receptor RORalpha in staggerer mice

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836105

Identification of nuclear receptor mRNAs by RT-PCR amplification of conserved zinc-finger motif sequences

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836105

Relationship between circadian oscillations of Rev-erbalpha expression and intracellular levels of its ligand, heme.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836105

Reciprocal regulation of haem biosynthesis and the circadian clock in mammals

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836105

Effect of glucose administration on cholesterol and bile acid metabolism in rats

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836105

The orphan nuclear receptor, RORalpha, regulates gene expression that controls lipid metabolism: staggerer (SG/SG) mice are resistant to diet-induced obesity.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836105

Prevention and treatment of obesity, insulin resistance, and diabetes by bile acid-binding resin.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836105

Reconstitution of functional nuclear receptor proteins using high pressure refolding.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836105

A comparative study of the conversion of 7-hydroxycholesterol in rabbit, guinea pig, rat, hamster, and chicken

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836105

Sterol efflux is impaired from macrophage foam cells selectively enriched with 7-ketocholesterol.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836105

Sterol metabolism—XLVI. Synthesis of oxidized cholesterol fatty acyl esters

29 November 2018

1 reference

12 December 2020

Effects of drugs and sterols on cholesterol 7 alpha-hydroxylase activity in rat liver microsomes

1 reference

12 December 2020

Binding of cholesterol to cytochromes P-450 from rabbit liver microsomes

1 reference

12 December 2020

Serum concentration of 7 alpha-hydroxycholesterol as an indicator of bile acid synthesis in humans

1 reference

12 December 2020

7-Hydroperoxycholesterol and its products in oxidized low density lipoprotein and human atherosclerotic plaque

1 reference

12 December 2020

Severe atherosclerosis and hypoalphalipoproteinemia in the staggerer mouse, a mutant of the nuclear receptor RORalpha

1 reference

12 December 2020

Oxysterols and atherosclerosis

1 reference

12 December 2020

Increased plasma levels of oxysterols, in vivo markers of oxidative stress, in patients with familial combined hyperlipidemia: Reduction during atorvastatin and fenofibrate therapy

1 reference

12 December 2020

Expression and regulation of the nuclear receptor RORalpha in human vascular cells

1 reference

12 December 2020

The Deuterator: software for the determination of backbone amide deuterium levels from H/D exchange MS data

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M109.080614

7 January 2021

inferred from DOI database lookup

RZRs, a new family of retinoid-related orphan receptors that function as both monomers and homodimers

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M109.080614

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1074/JBC.M109.080614

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19965867%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19965867%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

2 references