(Q24338659)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23597562%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

title

Inhibition of tumor angiogenesis and growth by a small-molecule multi-FGF receptor blocker with allosteric properties (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23597562%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

8-cyclopentyl-1,3-dipropylxanthine

73283

1 reference

1 reference

1 reference

1 reference

1 reference

sodium 2-amino-5-[(1-methoxy-2-methylindolizin-3-yl)carbonyl]benzoate

73295

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

methoctramine hydrochloride

73287

1 reference

acetyl-beta-methylthiocholine iodide

73452

1 reference

1 reference

1 reference

1 reference

acetyl-beta-methylthiocholine

73289

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23597562%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Katrien De Bock

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23597562%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Maria Georgiadou

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23597562%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Massimiliano Mazzone

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23597562%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Serena Zacchigna

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23597562%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Carmen Ruiz De Almodovar

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23597562%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Inmaculada Segura

27

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23597562%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Toru Shimada

34

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23597562%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Agnes Noel

37

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23597562%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Paul Schaeffer

42

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23597562%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Harald Schwalbe

45

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23597562%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Francesco Luigi Gervasio

46

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23597562%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Michael Simons

50

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23597562%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Arthur Christopoulos

51

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23597562%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

53

Peter Carmeliet

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23597562%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

41

Susumu Katsuma

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23597562%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

47

Geert Carmeliet

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23597562%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

1

Françoise Bono

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23597562%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

52

Jean-Marc Herbert

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23597562%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

3

Corentin Herbert

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23597562%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

7

Marc Tjwa

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23597562%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

8

Chantal Alcouffe

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23597562%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

10

Marc Bianciotto

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23597562%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

11

Bart Jonckx

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23597562%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

14

Christof Michielsen

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23597562%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

15

David Sibrac

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23597562%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

19

Jean-Pascal Herault

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23597562%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

21

Patrice Rigon

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23597562%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

23

Filip Claes

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23597562%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

25

Koen Poesen

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23597562%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

36

Silvia Blacher

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23597562%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

44

Ann Van Schepdael

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23597562%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

30

Diether Lambrechts

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23597562%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

author name string

Pierre Fons

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23597562%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Annelii Ny

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23597562%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Masahiro Murakami

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23597562%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Anthony A Lanahan

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23597562%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Frédérique Dol-Gleizes

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23597562%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Christian Fischer

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23597562%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Isabelle Blanc

24

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23597562%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Jie Zhang

26

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23597562%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Geneviève Gueguen

28

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23597562%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Marie-Françoise Bordes

29

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23597562%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Roselyne Broussy

31

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23597562%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Marlies van de Wouwer

32

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23597562%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Corinne Michaux

33

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23597562%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Isabelle Jean

35

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23597562%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Patrick Motte

38

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23597562%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Eran Rom

39

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23597562%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Jean-Marie Rakic

40

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23597562%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Avner Yayon

43

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23597562%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Jef Rozensky

48

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23597562%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Mieke Dewerchin

49

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23597562%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

language of work or name

English

0 references

publication date

1 April 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23597562%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23597562%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

volume

23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23597562%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23597562%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

page(s)

477-488

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23597562%20AND%20SRC:MED&resulttype=core&format=json

Modulation of several waves of gene expression during FGF-1 induced epithelial-mesenchymal transition of carcinoma cells

28 February 2020

cites work

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2013.02.019

7 January 2021

Allosteric mechanisms of G protein-Coupled Receptor signaling: a structural perspective

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2013.02.019

7 January 2021

FGF receptor inhibitors: role in cancer therapy

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2013.02.019

7 January 2021

Mechanisms of FGFR-mediated carcinogenesis

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2013.02.019

7 January 2021

RO4383596, an orally active KDR, FGFR, and PDGFR inhibitor: synthesis and biological evaluation

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2013.02.019

7 January 2021

Growth hormone, VEGF and FGF: involvement in rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2013.02.019

7 January 2021

Drug resistance by evasion of antiangiogenic targeting of VEGF signaling in late-stage pancreatic islet tumors

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2013.02.019

7 January 2021

Effective suppression of vascular network formation by combination of antibodies blocking VEGFR ligand binding and receptor dimerization

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2013.02.019

7 January 2021

Molecular mechanism of SSR128129E, an extracellularly acting, small-molecule, allosteric inhibitor of FGF receptor signaling

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2013.02.019

7 January 2021

Anti-PlGF inhibits growth of VEGF(R)-inhibitor-resistant tumors without affecting healthy vessels

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2013.02.019

7 January 2021

Heterozygous deficiency of PHD2 restores tumor oxygenation and inhibits metastasis via endothelial normalization

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2013.02.019

7 January 2021

Cell signaling by receptor tyrosine kinases

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2013.02.019

7 January 2021

https://api.crossref.org/works/10.1016%2FJ.CCR.2013.02.019

1 reference

7 January 2021

Allosteric modulation of G protein-coupled receptors: a pharmacological perspective.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2013.02.019

7 January 2021

Allosteric GPCR modulators: taking advantage of permissive receptor pharmacology.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2013.02.019

7 January 2021

Monoclonal antibodies targeting the VEGF receptor-2 (Flk1/KDR) as an anti-angiogenic therapeutic strategy

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2013.02.019

7 January 2021

Fibroblast growth factor 2 control of vascular tone

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2013.02.019

7 January 2021

VEGF modulates erythropoiesis through regulation of adult hepatic erythropoietin synthesis.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2013.02.019

7 January 2021

Modes of resistance to anti-angiogenic therapy

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2013.02.019

7 January 2021

Fibroblast growth factor signalling: from development to cancer

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2013.02.019

7 January 2021

Allosteric modulators of GPCRs: a novel approach for the treatment of CNS disorders

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2013.02.019

7 January 2021

The FGF family: biology, pathophysiology and therapy

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2013.02.019

7 January 2021

Allosteric binding sites on cell-surface receptors: novel targets for drug discovery

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2013.02.019

7 January 2021

Fibroblast growth factors and their receptors in cancer

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2013.02.019

7 January 2021

Role of basic fibroblast growth factor-2 in epithelial-mesenchymal transformation

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2013.02.019

7 January 2021

Positive allosteric modulators of metabotropic glutamate 1 receptor: characterization, mechanism of action, and binding site

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2013.02.019

7 January 2021

Targeted disruption of fibroblast growth factor (FGF) receptor 2 suggests a role for FGF signaling in pregastrulation mammalian development

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2013.02.019

7 January 2021

Allosteric peptide activators of pro-hepatocyte growth factor stimulate Met signaling

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2013.02.019

7 January 2021

Fibroblast growth factors: from molecular evolution to roles in development, metabolism and disease

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2013.02.019

7 January 2021

Fibroblast growth factor regulation of neovascularization

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2013.02.019

7 January 2021

Fibroblast growth factor signals regulate a wave of Hedgehog activation that is essential for coronary vascular development

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2013.02.019

7 January 2021

Functional Selectivity and Classical Concepts of Quantitative Pharmacology

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2013.02.019

7 January 2021

Allosteric modulation of the cannabinoid CB1 receptor

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2013.02.019

7 January 2021

G protein-coupled receptor allosterism and complexing

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2013.02.019

7 January 2021

Compensation by fibroblast growth factor 1 (FGF1) does not account for the mild phenotypic defects observed in FGF2 null mice.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2013.02.019

7 January 2021

Developmental and pathological angiogenesis

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2013.02.019

7 January 2021

Allosteric Modulation of G Protein–Coupled Receptors

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2013.02.019

7 January 2021

VEGF and c-Met blockade amplify angiogenesis inhibition in pancreatic islet cancer

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2013.02.019

7 January 2021

Antibody-based targeting of FGFR3 in bladder carcinoma and t(4;14)-positive multiple myeloma in mice

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2013.02.019

7 January 2021

Thermodynamic and structural description of allosterically regulated VEGFR-2 dimerization

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2013.02.019

7 January 2021

The Fgf families in humans, mice, and zebrafish: their evolutional processes and roles in development, metabolism, and disease

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2013.02.019

7 January 2021

Basic fibroblast growth factor stimulates osteoclast recruitment, development, and bone pit resorption in association with angiogenesis in vivo on the chick chorioallantoic membrane and activates isolated avian osteoclast resorption in vitro

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2013.02.019

7 January 2021

Functions of paracrine PDGF signaling in the proangiogenic tumor stroma revealed by pharmacological targeting

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2013.02.019

7 January 2021

Inflammatory cells and chemokines sustain FGF2-induced angiogenesis.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2013.02.019

7 January 2021

Small molecule kinase inhibitors as anti-cancer therapeutics

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2013.02.019

7 January 2021

Massive T-lymphocyte infiltration into the host stroma is essential for fibroblast growth factor-2-promoted growth and metastasis of mammary tumors via neovascular stability.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2013.02.019

7 January 2021

Tinkering outside the kinase ATP box: allosteric (type IV) and bivalent (type V) inhibitors of protein kinases

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2013.02.019

7 January 2021

10.1016/J.CCR.2013.02.019

Identifiers

DOI

2 references

Consolidated OpenCitations Corpus – April 2017

2753969

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23597562%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

2753969

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

2 references

2753969

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23597562%20AND%20SRC:MED&resulttype=core&format=json