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Apaf1 is required for mitochondrial pathways of apoptosis and brain development
scientific journal article
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instance of
scholarly article
1 reference
stated in
PubMed
PubMed ID
9753321
retrieved
24 January 2017
title
Apaf1 is required for mitochondrial pathways of apoptosis and brain development
(English)
1 reference
stated in
PubMed
PubMed ID
9753321
retrieved
24 January 2017
main subject
brain
0 references
apoptotic process
0 references
Apoptotic peptidase activating factor 1
1 reference
stated in
GOA release 2020-03-11
mitochondrion
1 reference
based on heuristic
inferred from title
author
Razq Hakem
object named as
R. Hakem
series ordinal
6
0 references
Josef Penninger
series ordinal
7
object named as
J. M. Penninger
1 reference
stated in
PubMed
PubMed ID
9753321
retrieved
24 January 2017
author name string
H. Yoshida
series ordinal
1
1 reference
stated in
PubMed
PubMed ID
9753321
retrieved
24 January 2017
Y. Y. Kong
series ordinal
2
1 reference
stated in
PubMed
PubMed ID
9753321
retrieved
24 January 2017
R. Yoshida
series ordinal
3
1 reference
stated in
PubMed
PubMed ID
9753321
retrieved
24 January 2017
A. J. Elia
series ordinal
4
1 reference
stated in
PubMed
PubMed ID
9753321
retrieved
24 January 2017
A. Hakem
series ordinal
5
1 reference
stated in
PubMed
PubMed ID
9753321
retrieved
24 January 2017
T. W. Mak
series ordinal
8
1 reference
stated in
PubMed
PubMed ID
9753321
retrieved
24 January 2017
language of work or name
English
0 references
publication date
18 September 1998
1 reference
stated in
PubMed
PubMed ID
9753321
retrieved
24 January 2017
published in
Cell
1 reference
stated in
PubMed
PubMed ID
9753321
retrieved
24 January 2017
volume
94
1 reference
stated in
PubMed
PubMed ID
9753321
retrieved
24 January 2017
page(s)
739–750
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stated in
PubMed
PubMed ID
9753321
retrieved
24 January 2017
issue
6
1 reference
stated in
PubMed
PubMed ID
9753321
retrieved
24 January 2017
cites work
Fas-induced activation of the cell death-related protease CPP32 Is inhibited by Bcl-2 and by ICE family protease inhibitors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981733-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Trophic factors and neuronal survival
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981733-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bcl-x(L) can inhibit apoptosis in cells that have undergone Fas-induced protease activation
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981733-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mitochondrial cytochrome c release in apoptosis occurs upstream of DEVD-specific caspase activation and independently of mitochondrial transmembrane depolarization.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981733-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Numbers, time and neocortical neuronogenesis: a general developmental and evolutionary model
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981733-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apaf1 (CED-4 homolog) regulates programmed cell death in mammalian development
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981733-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interaction of CED-4 with CED-3 and CED-9: a molecular framework for cell death
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981733-X
retrieved
7 January 2021
based on heuristic
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Nineteenth century research on naturally occurring cell death and related phenomena
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981733-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genetic control of programmed cell death in the nematode C. elegans.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981733-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Controlling cell death
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981733-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential requirement for caspase 9 in apoptotic pathways in vivo.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981733-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
C. elegans cell survival gene ced-9 encodes a functional homolog of the mammalian proto-oncogene bcl-2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981733-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981733-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The CARD domain: a new apoptotic signalling motif
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981733-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutations that affect neural cell lineages and cell fates during the development of the nematode Caenorhabditis elegans
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981733-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bcl-XL interacts with Apaf-1 and inhibits Apaf-1-dependent caspase-9 activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981733-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A mouse model of greig cephalopolysyndactyly syndrome: the extra-toesJ mutation contains an intragenic deletion of the Gli3 gene
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981733-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Role of Ced-3/ICE-family proteases in staurosporine-induced programmed cell death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981733-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Programmed cell death in animal development
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981733-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981733-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bcl-2: a repressor of lymphocyte death
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981733-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The biochemistry of programmed cell death
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981733-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mitochondrial control of apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981733-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981733-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981733-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Induction of apoptosis by the mouse Nedd2 gene, which encodes a protein similar to the product of the Caenorhabditis elegans cell death gene ced-3 and the mammalian IL-1 beta-converting enzyme
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981733-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981733-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of caspase-2 in apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981733-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981733-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981733-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
FLICE is activated by association with the CD95 death-inducing signaling complex (DISC).
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981733-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981733-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apoptosis by death factor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981733-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caspases: killer proteases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981733-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cell death during development of the nervous system
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981733-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Control of embryonic motoneuron survival in vivo by ciliary neurotrophic factor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981733-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caspase-9, Bcl-XL, and Apaf-1 form a ternary complex
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981733-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Alterations in mitochondrial structure and function are early events of dexamethasone-induced thymocyte apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981733-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bcl-2 and the regulation of programmed cell death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981733-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Two CD95 (APO-1/Fas) signaling pathways
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981733-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
bcl-2 inhibits multiple forms of apoptosis but not negative selection in thymocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981733-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Developing Caenorhabditis elegans neurons may contain both cell-death protective and killer activities
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981733-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interaction between the C. elegans cell-death regulators CED-9 and CED-4.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981733-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular ordering of the Fas-apoptotic pathway: the Fas/APO-1 protease Mch5 is a CrmA-inhibitable protease that activates multiple Ced-3/ICE-like cysteine proteases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981733-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
T-cell apoptosis detected in situ during positive and negative selection in the thymus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981733-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The central executioner of apoptosis: multiple connections between protease activation and mitochondria in Fas/APO-1/CD95- and ceramide-induced apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981733-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The cell cycle of the pseudostratified ventricular epithelium of the embryonic murine cerebral wall
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981733-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cloning and functional analysis of BAG-1: a novel Bcl-2-binding protein with anti-cell death activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981733-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caspases: key mediators of apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981733-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Developmental and genetic regulation of programmed neuronal death.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981733-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Essential contribution of caspase 3/CPP32 to apoptosis and its associated nuclear changes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981733-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interaction and regulation of the Caenorhabditis elegans death protease CED-3 by CED-4 and CED-9.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981733-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interaction and regulation of subcellular localization of CED-4 by CED-9
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981733-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981733-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The transcription factor NF-ATc1 regulates lymphocyte proliferation and Th2 cytokine production
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981733-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta-converting enzyme
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981733-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981733-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981733-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Distantly related sequences in the alpha- and beta-subunits of ATP synthase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981733-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0092-8674(00)81733-X
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1367518
OpenCitations bibliographic resource ID
1367518
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1367518
PubMed ID
9753321
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1367518
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