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How cells read TGF-beta signals
scientific article (publication date: December 2000)
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scholarly article
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review article
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stated in
Europe PubMed Central
title
How cells read TGF-beta signals
(English)
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stated in
PubMed
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=11252892
retrieved
30 April 2017
main subject
type II transforming growth factor beta receptor binding
1 reference
stated in
Gene Ontology release 2020-05-02
Gene Ontology ID
GO:0005114
author name string
Massagué J
series ordinal
1
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stated in
PubMed
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=11252892
retrieved
30 April 2017
language of work or name
English
1 reference
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PubMed
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30 April 2017
publication date
December 2000
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PubMed
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=11252892
retrieved
30 April 2017
published in
Nature Reviews Molecular Cell Biology
1 reference
stated in
PubMed
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=11252892
retrieved
30 April 2017
volume
1
1 reference
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PubMed
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=11252892
retrieved
30 April 2017
issue
3
1 reference
stated in
PubMed
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=11252892
retrieved
30 April 2017
page(s)
169-78
1 reference
stated in
PubMed
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=11252892
retrieved
30 April 2017
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Functional consequences of tumorigenic missense mutations in the amino-terminal domain of Smad4
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Crystal structure of a Smad MH1 domain bound to DNA: insights on DNA binding in TGF-beta signaling
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Regulation of intracellular dynamics of Smad4 by its leucine-rich nuclear export signal
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Identification of two Smad4 proteins in Xenopus. Their common and distinct properties.
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Determinants of specificity in TGF-beta signal transduction.
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Xenopus Mad proteins transduce distinct subsets of signals for the TGF beta superfamily.
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A novel mesoderm inducer, Madr2, functions in the activin signal transduction pathway
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The novel Cer-like protein Caronte mediates the establishment of embryonic left-right asymmetry
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Antagonistic signaling by Caronte, a novel Cerberus-related gene, establishes left-right asymmetric gene expression
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Left-right asymmetric expression of lefty2 and nodal is induced by a signaling pathway that includes the transcription factor FAST2
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A kinase subdomain of transforming growth factor-beta (TGF-beta) type I receptor determines the TGF-beta intracellular signaling specificity
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The role of FAST-1 and Smads in transcriptional regulation by activin during early Xenopus embryogenesis
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Specificity in transforming growth factor beta-induced transcription of the plasminogen activator inhibitor-1 gene: interactions of promoter DNA, transcription factor muE3, and Smad proteins
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7 January 2021
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A transcriptional partner for MAD proteins in TGF-beta signalling
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Smad3 and Smad4 cooperate with c-Jun/c-Fos to mediate TGF-beta-induced transcription
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35043051
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7 January 2021
based on heuristic
inferred from DOI database lookup
Expression of the PEBP2alphaA/AML3/CBFA1 gene is regulated by BMP4/7 heterodimer and its overexpression suppresses type I collagen and osteocalcin gene expression in osteoblastic and nonosteoblastic mesenchymal cells
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Smad and AML proteins synergistically confer transforming growth factor beta1 responsiveness to human germ-line IgA genes
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Interaction and functional cooperation of PEBP2/CBF with Smads. Synergistic induction of the immunoglobulin germline Calpha promoter
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35043051
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7 January 2021
based on heuristic
inferred from DOI database lookup
Interaction between Wnt and TGF-beta signalling pathways during formation of Spemann's organizer.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35043051
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7 January 2021
based on heuristic
inferred from DOI database lookup
Association of Smads with lymphoid enhancer binding factor 1/T cell-specific factor mediates cooperative signaling by the transforming growth factor-beta and wnt pathways
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2F35043051
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7 January 2021
based on heuristic
inferred from DOI database lookup
A Smad transcriptional corepressor
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
The Ski oncoprotein interacts with the Smad proteins to repress TGFbeta signaling
1 reference
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7 January 2021
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SnoN and Ski protooncoproteins are rapidly degraded in response to transforming growth factor beta signaling
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Distinctive gene expression patterns in human mammary epithelial cells and breast cancers
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Negative feedback regulation of TGF-beta signaling by the SnoN oncoprotein
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7 January 2021
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Mutations in TGIF cause holoprosencephaly and link NODAL signalling to human neural axis determination
1 reference
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Crossref
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7 January 2021
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inferred from DOI database lookup
Induction of the zebrafish ventral brain and floorplate requires cyclops/nodal signalling.
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Smad2 role in mesoderm formation, left-right patterning and craniofacial development
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
TGF-beta induces fibronectin synthesis through a c-Jun N-terminal kinase-dependent, Smad4-independent pathway
1 reference
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Crossref
reference URL
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7 January 2021
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Involvement of the p38 mitogen-activated protein kinase pathway in transforming growth factor-beta-induced gene expression
1 reference
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Crossref
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7 January 2021
based on heuristic
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ATF-2 is a common nuclear target of Smad and TAK1 pathways in transforming growth factor-beta signaling
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35043051
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7 January 2021
based on heuristic
inferred from DOI database lookup
TAK1 participates in c-Jun N-terminal kinase signaling during Drosophila development
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35043051
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7 January 2021
based on heuristic
inferred from DOI database lookup
TAB1: an activator of the TAK1 MAPKKK in TGF-beta signal transduction
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35043051
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7 January 2021
based on heuristic
inferred from DOI database lookup
XIAP, a cellular member of the inhibitor of apoptosis protein family, links the receptors to TAB1-TAK1 in the BMP signaling pathway
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35043051
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7 January 2021
based on heuristic
inferred from DOI database lookup
Interdependent SMAD and JNK signaling in transforming growth factor-beta-mediated transcription
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35043051
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7 January 2021
based on heuristic
inferred from DOI database lookup
Smad3-Smad4 and AP-1 complexes synergize in transcriptional activation of the c-Jun promoter by transforming growth factor beta
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35043051
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7 January 2021
based on heuristic
inferred from DOI database lookup
Signaling inputs converge on nuclear effectors in TGF-beta signaling
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35043051
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7 January 2021
based on heuristic
inferred from DOI database lookup
Hedgehog creates a gradient of DPP activity in Drosophila wing imaginal discs.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35043051
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7 January 2021
based on heuristic
inferred from DOI database lookup
The MAD-related protein Smad7 associates with the TGFbeta receptor and functions as an antagonist of TGFbeta signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35043051
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of Smad7, a TGFbeta-inducible antagonist of TGF-beta signalling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35043051
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of transforming growth factor-beta/SMAD signalling by the interferon-gamma/STAT pathway.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35043051
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Opposing BMP and EGF signalling pathways converge on the TGF-beta family mediator Smad1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35043051
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A mechanism of repression of TGFbeta/ Smad signaling by oncogenic Ras
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35043051
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ras pathway specificity is determined by the integration of multiple signal-activated and tissue-restricted transcription factors.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35043051
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7 January 2021
based on heuristic
inferred from DOI database lookup
Silencing of TGF-beta signalling by the pseudoreceptor BAMBI.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35043051
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7 January 2021
based on heuristic
inferred from DOI database lookup
Daughters against dpp modulates dpp organizing activity in Drosophila wing development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35043051
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Smad6 inhibits BMP/Smad1 signaling by specifically competing with the Smad4 tumor suppressor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35043051
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Evidence for a role of Smad6 in chick cardiac development.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35043051
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Smad7 and Smad6 differentially modulate transforming growth factor beta -induced inhibition of embryonic lung morphogenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35043051
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A role for smad6 in development and homeostasis of the cardiovascular system
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35043051
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Smad6 inhibits signalling by the TGF-beta superfamily.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35043051
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Betaglycan presents ligand to the TGF beta signaling receptor.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35043051
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Betaglycan binds inhibin and can mediate functional antagonism of activin signalling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35043051
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Signal relay by BMP antagonism controls the SHH/FGF4 feedback loop in vertebrate limb buds.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35043051
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bone morphogenetic proteins induce the expression of noggin, which limits their activity in cultured rat osteoblasts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35043051
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Thrombospondin-1 is a major activator of TGF-beta1 in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35043051
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Responses of embryonic Xenopus cells to activin and FGF are separated by multiple dose thresholds and correspond to distinct axes of the mesoderm.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35043051
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The interpretation of position in a morphogen gradient as revealed by occupancy of activin receptors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35043051
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TGF-beta1 and Ha-Ras collaborate in modulating the phenotypic plasticity and invasiveness of epithelial tumor cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35043051
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Synergistic signaling in fetal brain by STAT3-Smad1 complex bridged by p300
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35043051
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35043051
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35043051
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Missense mutations abolishing DNA binding of the osteoblast-specific transcription factor OSF2/CBFA1 in cleidocranial dysplasia.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35043051
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutations involving the transcription factor CBFA1 cause cleidocranial dysplasia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35043051
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mixer, a homeobox gene required for endoderm development.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35043051
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Crystal structure of the cytoplasmic domain of the type I TGF beta receptor in complex with FKBP12
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35043051
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A structural basis for mutational inactivation of the tumour suppressor Smad4
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35043051
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structural basis of Smad2 recognition by the Smad anchor for receptor activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35043051
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Drosophila Mad binds to DNA and directly mediates activation of vestigial by Decapentaplegic
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35043051
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A human Mad protein acting as a BMP-regulated transcriptional activator
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35043051
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
BF-1 interferes with transforming growth factor beta signaling by associating with Smad partners
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35043051
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/35043051
2 references
stated in
PubMed
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=11252892
retrieved
30 April 2017
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
613402
Dimensions Publication ID
1013794936
0 references
Fatcat ID
release_xu7ed6bpi5hwjhcs5nhe7nik4i
1 reference
stated in
Fatcat
reference URL
https://api.fatcat.wiki/v0/release/xu7ed6bpi5hwjhcs5nhe7nik4i
retrieved
24 November 2022
based on heuristic
mapped directly with Wikidata item
OpenCitations bibliographic resource ID
613402
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
613402
PubMed ID
11252892
2 references
stated in
PubMed
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=11252892
retrieved
30 April 2017
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
613402
ResearchGate publication ID
12079421
0 references
Springer Nature article ID
10.1038/35043051
0 references
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