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Nucleocytoplasmic shuttling of Smad proteins
scientific article published on January 2009
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
19114992
retrieved
19 August 2017
review article
1 reference
stated in
Europe PubMed Central
title
Nucleocytoplasmic shuttling of Smad proteins
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
19114992
retrieved
19 August 2017
main subject
co-SMAD binding
1 reference
stated in
Gene Ontology release 2020-05-02
Gene Ontology ID
GO:0070410
R-SMAD binding
1 reference
stated in
Gene Ontology release 2020-05-02
Gene Ontology ID
GO:0070412
I-SMAD binding
1 reference
stated in
Gene Ontology release 2020-05-02
Gene Ontology ID
GO:0070411
author
Caroline S. Hill
object named as
Caroline S Hill
series ordinal
1
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publication date
1 January 2009
1 reference
stated in
Europe PubMed Central
PubMed ID
19114992
retrieved
19 August 2017
published in
Cell Research
1 reference
stated in
Europe PubMed Central
PubMed ID
19114992
retrieved
19 August 2017
volume
19
1 reference
stated in
Europe PubMed Central
PubMed ID
19114992
retrieved
19 August 2017
issue
1
1 reference
stated in
Europe PubMed Central
PubMed ID
19114992
retrieved
19 August 2017
page(s)
36-46
1 reference
stated in
Europe PubMed Central
PubMed ID
19114992
retrieved
19 August 2017
exact match
https://scigraph.springernature.com/pub.10.1038/cr.2008.325
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cites work
TGFbeta in Cancer
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TGF-beta signal transduction
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Mechanisms of TGF-beta signaling from cell membrane to the nucleus
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Cancer-associated transforming growth factor beta type II receptor gene mutant causes activation of bone morphogenic protein-Smads and invasive phenotype
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https://api.crossref.org/works/10.1038%2FCR.2008.325
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Transforming growth factor beta-induced Smad1/5 phosphorylation in epithelial cells is mediated by novel receptor complexes and is essential for anchorage-independent growth
1 reference
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Activin receptor-like kinase (ALK)1 is an antagonistic mediator of lateral TGFbeta/ALK5 signaling
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https://api.crossref.org/works/10.1038%2FCR.2008.325
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How the Smads regulate transcription
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https://api.crossref.org/works/10.1038%2FCR.2008.325
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7 January 2021
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inferred from DOI database lookup
Molecular and functional consequences of Smad4 C-terminal missense mutations in colorectal tumour cells
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https://api.crossref.org/works/10.1038%2FCR.2008.325
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7 January 2021
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Dual role of the Smad4/DPC4 tumor suppressor in TGFbeta-inducible transcriptional complexes
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7 January 2021
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Attenuation of the TGF-beta-Smad signaling pathway in pancreatic tumor cells confers resistance to TGF-beta-induced growth arrest.
1 reference
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https://api.crossref.org/works/10.1038%2FCR.2008.325
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7 January 2021
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Smurf1 interacts with transforming growth factor-beta type I receptor through Smad7 and induces receptor degradation
1 reference
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https://api.crossref.org/works/10.1038%2FCR.2008.325
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7 January 2021
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Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF beta receptor for degradation
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2008.325
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7 January 2021
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GADD34-PP1c recruited by Smad7 dephosphorylates TGFbeta type I receptor
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reference URL
https://api.crossref.org/works/10.1038%2FCR.2008.325
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7 January 2021
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Crystal Structure of a Phosphorylated Smad2
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reference URL
https://api.crossref.org/works/10.1038%2FCR.2008.325
retrieved
7 January 2021
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inferred from DOI database lookup
Ubiquitin-dependent degradation of TGF-beta-activated smad2.
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2FCR.2008.325
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7 January 2021
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CRM1 is an export receptor for leucine-rich nuclear export signals
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2008.325
retrieved
7 January 2021
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inferred from DOI database lookup
Regulation of intracellular dynamics of Smad4 by its leucine-rich nuclear export signal
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2008.325
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transforming growth factor beta-independent shuttling of Smad4 between the cytoplasm and nucleus.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2008.325
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Smad2 nucleocytoplasmic shuttling by nucleoporins CAN/Nup214 and Nup153 feeds TGFbeta signaling complexes in the cytoplasm and nucleus
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2008.325
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7 January 2021
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Using viral species specificity to define a critical protein/RNA interaction surface
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2008.325
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7 January 2021
based on heuristic
inferred from DOI database lookup
Kinesin-mediated transport of Smad2 is required for signaling in response to TGF-beta ligands.
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reference URL
https://api.crossref.org/works/10.1038%2FCR.2008.325
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Analysis of Smad nucleocytoplasmic shuttling in living cells.
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2008.325
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7 January 2021
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inferred from DOI database lookup
Kinetic analysis of Smad nucleocytoplasmic shuttling reveals a mechanism for transforming growth factor beta-dependent nuclear accumulation of Smads
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2008.325
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7 January 2021
based on heuristic
inferred from DOI database lookup
Nucleocytoplasmic shuttling of Smads 2, 3, and 4 permits sensing of TGF-beta receptor activity
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2008.325
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7 January 2021
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SB-431542 is a potent and specific inhibitor of transforming growth factor-beta superfamily type I activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2FCR.2008.325
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7 January 2021
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Inhibition of transforming growth factor (TGF)-beta1-induced extracellular matrix with a novel inhibitor of the TGF-beta type I receptor kinase activity: SB-431542
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2008.325
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nuclear targeting of transforming growth factor-beta-activated Smad complexes
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2008.325
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7 January 2021
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inferred from DOI database lookup
Identification of phosphatases for Smad in the BMP/DPP pathway
1 reference
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https://api.crossref.org/works/10.1038%2FCR.2008.325
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7 January 2021
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Unique players in the BMP pathway: small C-terminal domain phosphatases dephosphorylate Smad1 to attenuate BMP signaling.
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2FCR.2008.325
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7 January 2021
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PPM1A functions as a Smad phosphatase to terminate TGFbeta signaling
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2FCR.2008.325
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7 January 2021
based on heuristic
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Pushing the envelope: structure, function, and dynamics of the nuclear periphery
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2008.325
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7 January 2021
based on heuristic
inferred from DOI database lookup
Transport between the cell nucleus and the cytoplasm
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2008.325
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nucleocytoplasmic shuttling of signal transducers.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2008.325
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A distinct nuclear localization signal in the N terminus of Smad 3 determines its ligand-induced nuclear translocation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2008.325
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Importin beta mediates nuclear translocation of Smad 3
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2008.325
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transforming growth factor-beta induces nuclear import of Smad3 in an importin-beta1 and Ran-dependent manner
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2008.325
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
In or out? The dynamics of Smad nucleocytoplasmic shuttling
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2008.325
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nucleocytoplasmic shuttling of Smad1 conferred by its nuclear localization and nuclear export signals
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2008.325
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An extended bipartite nuclear localization signal in Smad4 is required for its nuclear import and transcriptional activity
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2FCR.2008.325
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Distinct domain utilization by Smad3 and Smad4 for nucleoporin interaction and nuclear import.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2008.325
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7 January 2021
based on heuristic
inferred from DOI database lookup
Msk is required for nuclear import of TGF-{beta}/BMP-activated Smads
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2008.325
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7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of two Smad4 proteins in Xenopus. Their common and distinct properties.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2008.325
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7 January 2021
based on heuristic
inferred from DOI database lookup
A novel nuclear export signal in Smad1 is essential for its signaling activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2008.325
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The mechanism of nuclear export of Smad3 involves exportin 4 and Ran
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2008.325
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
SARA, a FYVE domain protein that recruits Smad2 to the TGFbeta receptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2008.325
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The nuclear import function of Smad2 is masked by SARA and unmasked by TGFbeta-dependent phosphorylation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2008.325
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7 January 2021
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TAZ controls Smad nucleocytoplasmic shuttling and regulates human embryonic stem-cell self-renewal
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Crossref
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7 January 2021
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Mathematical modeling identifies Smad nucleocytoplasmic shuttling as a dynamic signal-interpreting system
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2008.325
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7 January 2021
based on heuristic
inferred from DOI database lookup
TGFbeta-SMAD signal transduction: molecular specificity and functional flexibility
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2008.325
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7 January 2021
based on heuristic
inferred from DOI database lookup
Nucleocytoplasmic shuttling of STAT transcription factors.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2008.325
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7 January 2021
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inferred from DOI database lookup
Nuclear actin regulates dynamic subcellular localization and activity of the SRF cofactor MAL.
1 reference
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https://api.crossref.org/works/10.1038%2FCR.2008.325
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Getting the message across, STAT! Design principles of a molecular signaling circuit.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2008.325
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7 January 2021
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Identifiers
DOI
10.1038/CR.2008.325
1 reference
stated in
Europe PubMed Central
PubMed ID
19114992
retrieved
19 August 2017
Dimensions Publication ID
1046758489
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PubMed ID
19114992
1 reference
stated in
Europe PubMed Central
PubMed ID
19114992
retrieved
19 August 2017
ResearchGate publication ID
23712202
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