(Q39215637)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23292651%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

title

Small-molecule activation of the TRAIL receptor DR5 in human cancer cells (English)

1 reference

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21 February 2020

7

1 reference

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21 February 2020

author name string

Gelin Wang

1

1 reference

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21 February 2020

Xiaoming Wang

2

1 reference

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21 February 2020

Hong Yu

3

1 reference

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21 February 2020

Shuguang Wei

4

1 reference

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21 February 2020

Noelle Williams

5

1 reference

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21 February 2020

Daniel L Holmes

6

1 reference

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21 February 2020

Jacinth Naidoo

8

1 reference

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21 February 2020

Lai Wang

9

1 reference

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21 February 2020

Lin Li

10

1 reference

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21 February 2020

She Chen

11

1 reference

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21 February 2020

Patrick Harran

12

1 reference

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21 February 2020

Xiaoguang Lei

13

1 reference

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21 February 2020

Xiaodong Wang

14

1 reference

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21 February 2020

publication date

23 December 2012

1 reference

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21 February 2020

published in

Nature Chemical Biology

1 reference

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21 February 2020

volume

9

1 reference

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21 February 2020

issue

2

1 reference

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21 February 2020

page(s)

84-89

1 reference

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https://scigraph.springernature.com/pub.10.1038/nchembio.1153

21 February 2020

exact match

0 references

cites work

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FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2

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21 January 2018

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IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases

21 January 2018

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21 January 2018

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A small molecule Smac mimic potentiates TRAIL- and TNFalpha-mediated cell death

21 January 2018

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TNF-alpha induces two distinct caspase-8 activation pathways

21 January 2018

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Autocrine TNFalpha signaling renders human cancer cells susceptible to Smac-mimetic-induced apoptosis

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Ligand-based targeting of apoptosis in cancer: the potential of recombinant human apoptosis ligand 2/Tumor necrosis factor-related apoptosis-inducing ligand (rhApo2L/TRAIL).

21 January 2018

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cIAPs block Ripoptosome formation, a RIP1/caspase-8 containing intracellular cell death complex differentially regulated by cFLIP isoforms

21 January 2018

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21 January 2018

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21 January 2018

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Cullin3-based polyubiquitination and p62-dependent aggregation of caspase-8 mediate extrinsic apoptosis signaling

21 January 2018

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21 January 2018

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Death-receptor O-glycosylation controls tumor-cell sensitivity to the proapoptotic ligand Apo2L/TRAIL.

21 January 2018

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Smac agonists sensitize for Apo2L/TRAIL- or anticancer drug-induced apoptosis and induce regression of malignant glioma in vivo.

21 January 2018

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21 January 2018

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An apoptosis-inhibiting baculovirus gene with a zinc finger-like motif

21 January 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/23292651