(Q44155992)

30 November 2017

Golgi fragmentation occurs in the cells with prefibrillar alpha-synuclein aggregates and precedes the formation of fibrillar inclusion (English)

1 reference

30 November 2017

1 reference

Nirmal Gosavi

1

1 reference

30 November 2017

He-Jin Lee

2

1 reference

30 November 2017

Jun Sung Lee

3

1 reference

30 November 2017

Smita Patel

4

1 reference

30 November 2017

Seung-Jae Lee

5

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30 November 2017

language of work or name

English

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publication date

25 September 2002

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Journal of Biological Chemistry

30 November 2017

9

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based on heuristic

inferred from page(s)

published in

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30 November 2017

277

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30 November 2017

50

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30 November 2017

48984-48992

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Genetic classification of primary neurodegenerative disease.

30 November 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208194200

Fatal attractions: abnormal protein aggregation and neuron death in Parkinson's disease and Lewy body dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208194200

Alpha-synuclein and neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208194200

Fibrils formed in vitro from alpha-synuclein and two mutant forms linked to Parkinson's disease are typical amyloid

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208194200

Fiber diffraction of synthetic alpha-synuclein filaments shows amyloid-like cross-beta conformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208194200

Neuronal alpha-synucleinopathy with severe movement disorder in mice expressing A53T human alpha-synuclein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208194200

Chaperone suppression of alpha-synuclein toxicity in a Drosophila model for Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208194200

Acceleration of oligomerization, not fibrillization, is a shared property of both alpha-synuclein mutations linked to early-onset Parkinson's disease: implications for pathogenesis and therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208194200

Kinetic stabilization of the alpha-synuclein protofibril by a dopamine-alpha-synuclein adduct

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208194200

Formation and removal of alpha-synuclein aggregates in cells exposed to mitochondrial inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208194200

A detergent-insoluble membrane compartment contains A beta in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208194200

Dynamic nature of host-pathogen interactions in Mycobacterium marinum granulomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208194200

Membrane-bound alpha-synuclein has a high aggregation propensity and the ability to seed the aggregation of the cytosolic form

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208194200

The involvement of the Golgi apparatus in the pathogenesis of amyotrophic lateral sclerosis, Alzheimer's disease, and ricin intoxication

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208194200

Pathology of the inferior olivary nucleus in patients with multiple system atrophy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208194200

Accumulation of alpha-synuclein/NACP is a cytopathological feature common to Lewy body disease and multiple system atrophy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208194200

Filamentous alpha-synuclein inclusions link multiple system atrophy with Parkinson's disease and dementia with Lewy bodies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208194200

Widespread alterations of alpha-synuclein in multiple system atrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208194200

Characterization and dynamics of aggresome formation by a cytosolic GFP-chimera

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208194200

Hassles with taking out the garbage: aggravating aggresomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208194200

Aggresomes, inclusion bodies and protein aggregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208194200

Dynamic association of proteasomal machinery with the centrosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208194200

Overexpression of human alpha-synuclein causes dopamine neuron death in primary human mesencephalic culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208194200

alpha-Synuclein affects the MAPK pathway and accelerates cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208194200

The Golgi apparatus of spinal cord motor neurons in transgenic mice expressing mutant Cu,Zn superoxide dismutase becomes fragmented in early, preclinical stages of the disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208194200

Dopaminergic loss and inclusion body formation in alpha-synuclein mice: implications for neurodegenerative disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208194200

Ataxin-1 nuclear localization and aggregation: role in polyglutamine-induced disease in SCA1 transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208194200

Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208194200

Mutation of the E6-AP ubiquitin ligase reduces nuclear inclusion frequency while accelerating polyglutamine-induced pathology in SCA1 mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208194200

Polyglutamine-mediated dysfunction and apoptotic death of a Caenorhabditis elegans sensory neuron

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208194200

Genetic suppression of polyglutamine toxicity in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208194200

Formation of high molecular weight complexes of mutant Cu, Zn-superoxide dismutase in a mouse model for familial amyotrophic lateral sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208194200

Impairment of the ubiquitin-proteasome system by protein aggregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208194200

Scattered Golgi elements during microtubule disruption are initially enriched in trans-Golgi proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208194200

Vesicle permeabilization by protofibrillar alpha-synuclein: implications for the pathogenesis and treatment of Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208194200

Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208194200

Characterization of cytoplasmic alpha-synuclein aggregates. Fibril formation is tightly linked to the inclusion-forming process in cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208194200

Induction of neuronal death by α-synuclein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208194200

Mutant and wild type human alpha-synucleins assemble into elongated filaments with distinct morphologies in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208194200

Fragmentation of the Golgi apparatus of the ballooned neurons in patients with corticobasal degeneration and Creutzfeldt-Jakob disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208194200

Role of microtubules in the organization of the Golgi complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208194200

21 January 2018

Identifiers

DOI

10.1074/JBC.M208194200

1 reference

30 November 2017

1 reference