(Q100152552)

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Phosphorylation of STATs downstream of KIT mutants

An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-9670412)

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1 reference

8 July 2022

Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants

1 reference

8 July 2022

1 reference

8 July 2022

https://identifiers.org/reactome:R-HSA-9670412

1 reference

8 July 2022

8

object of statement has role

1 reference

8 July 2022

KIT mutant dimers:SFKs:p-JAK2:STATs [plasma membrane]

quantity

1

object of statement has role

1 reference

8 July 2022

8

object of statement has role

1 reference

8 July 2022

p-JAK2:SFKs:p-KIT mutants:p-STATs [plasma membrane]

quantity

1

object of statement has role

1 reference

8 July 2022

KIT mutant dimers:SFKs:p-JAK2:STATs [plasma membrane]

quantity

1

object of statement has role

1 reference

8 July 2022

STAT protein recruitment and activation in c-Kit deletion mutants

1 reference

8 July 2022

Signal transducer and activator of transcription 3 activation is required for Asp(816) mutant c-Kit-mediated cytokine-independent survival and proliferation in human leukemia cells

1 reference

8 July 2022

Juxtamembrane mutant V560GKit is more sensitive to Imatinib (STI571) compared with wild-type c-kit whereas the kinase domain mutant D816VKit is resistant.

1 reference

8 July 2022

Activation mutations of human c-KIT resistant to imatinib mesylate are sensitive to the tyrosine kinase inhibitor PKC412.

1 reference

8 July 2022

M-COPA suppresses endolysosomal Kit-Akt oncogenic signalling through inhibiting the secretory pathway in neoplastic mast cells.

1 reference

8 July 2022

Oncogenic signaling by Kit tyrosine kinase occurs selectively on the Golgi apparatus in gastrointestinal stromal tumors

1 reference

8 July 2022

Mechanisms of oncogenic KIT signal transduction in primary gastrointestinal stromal tumors (GISTs).

1 reference

8 July 2022

KIT oncogenic signaling mechanisms in imatinib-resistant gastrointestinal stromal tumor: PI3-kinase/AKT is a crucial survival pathway

1 reference

8 July 2022

Stat1 associates with c-kit and is activated in response to stem cell factor

1 reference

8 July 2022

Signal transduction via the stem cell factor receptor/c-Kit

1 reference

8 July 2022

Stem cell factor receptor/c-Kit: from basic science to clinical implications

1 reference

8 July 2022

Identifiers

1 reference

8 July 2022

(Q100152552)

Phosphorylation of STATs downstream of KIT mutants

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