(Q100166229)

English

EGR2 and SOX10-mediated initiation of Schwann cell myelination

An instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-9619665)

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8 July 2022

Nervous system development

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https://identifiers.org/reactome:R-HSA-9619665

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SOX10 dimer binds the POU3F1 promoter

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SOX10-dependent POU3F1 gene expression

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SOX10, POU3F1 and POU3F2 bind EGR2 gene

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Autocleavage of ADGRG6

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ADGRG heterodimer translocates to plasma membrane

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EGR2 and SOX10 bind the MAG gene

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EGR2 and SOX10 bind the MBP gene

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EGR2, SOX10 and SMARCA4 bind the MPZ gene

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EGR2, SOX10 and TEAD1 bind enhancers in the PMP22 gene

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PMP22 gene expression

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SOX10, EGR2 and NAB proteins bind the GJB1 promoter

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EGR2 and SOX10 bind the PRX gene

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L-PRX dimer binds DRP2

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L-PRX:DRP2 binds dystroglycan and laminin-211

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L-PRX:DRP:DGC:laminin-211 interacts with UTRN

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EGR2 and SREBF2(1-484) dimer bind HMGCR gene

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HMGCR gene expression

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EGR2 and SREBF2 dimer bind SCD5 gene

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EGR2 and SREBF2 dimer bind CYP51A1 gene

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CYP51A1 gene expression

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The origin and development of glial cells in peripheral nerves

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8 July 2022

The repair Schwann cell and its function in regenerating nerves

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8 July 2022

Schwann cell myelination

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Myelin synthesis in the peripheral nervous system.

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8 July 2022

The molecular machinery of myelin gene transcription in Schwann cells

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8 July 2022

Schwann cells and their transcriptional network: Evolution of key regulators of peripheral myelination

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8 July 2022

Identifiers

1 reference

8 July 2022

(Q100166229)

EGR2 and SOX10-mediated initiation of Schwann cell myelination

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