(Q101227000)

English

Small molecule inhibitor binds RIPK1, RIPK3

An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-9693978)

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1 reference

8 July 2022

negative regulation of programmed necrotic cell death

1 reference

8 July 2022

Regulation of necroptotic cell death

1 reference

8 July 2022

1 reference

8 July 2022

https://identifiers.org/reactome:R-HSA-9693978

1 reference

8 July 2022

RIPK1:RIPK3 [cytosol]

quantity

1

object of statement has role

1 reference

8 July 2022

small molecule inhibitors of RIPK1, RIPK3 [cytosol]

quantity

1

object of statement has role

1 reference

8 July 2022

RIPK1:RIPK3:sorafenib, ponatinib, pazopanib [cytosol]

quantity

1

object of statement has role

1 reference

8 July 2022

Sorafenib tosylate inhibits directly necrosome complex formation and protects in mouse models of inflammation and tissue injury.

1 reference

8 July 2022

A cellular screen identifies ponatinib and pazopanib as inhibitors of necroptosis.

1 reference

8 July 2022

Identifiers

1 reference

8 July 2022

(Q101227000)

Small molecule inhibitor binds RIPK1, RIPK3

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