(Q104580189)

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SOS1-mediated nucleotide exchange of RAS downstream of FLT3 fusion mutants

An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-9703441)

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1 reference

8 July 2022

Signaling by FLT3 fusion proteins

1 reference

8 July 2022

1 reference

8 July 2022

https://identifiers.org/reactome:R-HSA-9703441

1 reference

8 July 2022

p21 RAS:GDP [plasma membrane]

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1

object of statement has role

1 reference

8 July 2022

p21 RAS:GTP [plasma membrane]

quantity

1

object of statement has role

1 reference

8 July 2022

p-Y FLT3 fusions:GRB2:SOS1 [cytosol]

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1

object of statement has role

1 reference

8 July 2022

1

object of statement has role

1 reference

8 July 2022

1

object of statement has role

1 reference

8 July 2022

A constitutively active SPTBN1-FLT3 fusion in atypical chronic myeloid leukemia is sensitive to tyrosine kinase inhibitors and immunotherapy.

1 reference

8 July 2022

A novel t(3;13)(q13;q12) translocation fusing FLT3 with GOLGB1: toward myeloid/lymphoid neoplasms with eosinophilia and rearrangement of FLT3?

1 reference

8 July 2022

The juxtamembrane domain in ETV6/FLT3 is critical for PIM-1 up-regulation and cell proliferation

1 reference

8 July 2022

Direct binding of Grb2 has an important role in the development of myeloproliferative disease induced by ETV6/FLT3.

1 reference

8 July 2022

FMS-like Tyrosine Kinase 3/FLT3: From Basic Science to Clinical Implications

1 reference

8 July 2022

Identifiers

1 reference

8 July 2022

(Q104580189)

SOS1-mediated nucleotide exchange of RAS downstream of FLT3 fusion mutants

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