(Q106515457)

English

CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:p-Y-STAT1,3,5 dissociates yielding CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2 and p-Y-STAT1,3,5

An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-9674563)

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8 July 2022

Signaling by CSF3 (G-CSF)

1 reference

8 July 2022

1 reference

8 July 2022

https://identifiers.org/reactome:R-HSA-9674563

1 reference

8 July 2022

CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:p-Y-STAT1,3,5 [plasma membrane]

quantity

1

object of statement has role

1 reference

8 July 2022

CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-Y-SYK:p-HCK:p-TYK2 [plasma membrane]

quantity

1

object of statement has role

1 reference

8 July 2022

p-Y701-STAT1,p-Y705-STAT3,p-Y649-STAT5A,p-STAT5B [cytosol]

quantity

1

object of statement has role

1 reference

8 July 2022

Multiple signaling pathways induced by granulocyte colony-stimulating factor involving activation of JAKs, STAT5, and/or STAT3 are required for regulation of three distinct classes of immediate early genes

1 reference

8 July 2022

Rapid activation of the STAT3 transcription factor by granulocyte colony-stimulating factor

1 reference

8 July 2022

Tyrosine-dependent and -independent mechanisms of STAT3 activation by the human granulocyte colony-stimulating factor (G-CSF) receptor are differentially utilized depending on G-CSF concentration.

1 reference

8 July 2022

Identifiers

1 reference

8 July 2022

(Q106515457)

CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:p-Y-STAT1,3,5 dissociates yielding CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2 and p-Y-STAT1,3,5

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