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PPARA binds fibrates
An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-9734475)
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Statements
instance of
biological process
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9734475
part of
Regulation of lipid metabolism by PPARalpha
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9734475
found in taxon
Homo sapiens
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9734475
exact match
https://identifiers.org/reactome:R-HSA-9734475
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9734475
has part(s)
fibrates [nucleoplasm]
quantity
1
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9734475
PPARA:RXRA:Corepressors [nucleoplasm]
quantity
1
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9734475
Corepressors of PPARalpha [nucleoplasm]
quantity
1
object has role
product
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9734475
PPARA:RXRA:fibrates [nucleoplasm]
quantity
1
object has role
product
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9734475
cites work
Cell culture conditions determine apolipoprotein CIII secretion and regulation by fibrates in human hepatoma HepG2 cells
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9734475
N-(2-Benzoylphenyl)-L-tyrosine PPARgamma agonists. 1. Discovery of a novel series of potent antihyperglycemic and antihyperlipidemic agents
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9734475
Fibrate and statin synergistically increase the transcriptional activities of PPARalpha/RXRalpha and decrease the transactivation of NFkappaB.
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9734475
Discovery of gemfibrozil analogues that activate PPARα and enhance the expression of gene CPT1A involved in fatty acids catabolism.
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9734475
Anti-inflammatory and PPAR transactivational effects of secondary metabolites from the roots of Asarum sieboldii.
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9734475
The biochemical pharmacology of fenofibrate
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9734475
Identifiers
Reactome ID
R-HSA-9734475
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9734475
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