(Q14885358)

English

Dysferlin

mammalian protein found in Mus musculus

dystrophy-associated fer-1-like protein
Dysf
dysferlin
fer-1-like protein 1
dysferlin_a
dysferlin variant a

In more languages

Statements

1 reference

25 May 2022

UniProt protein ID

C2 domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9ESD7

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9ESD7

membrane protein

1 reference

based on heuristic

inferred from GOA cell component → membrane

Ferlin, C-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Ferlin A-domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

C2 domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Ferlin, second C2 domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Ferlin, first C2 domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

FerIin domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Ferlin, third C2 domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Ferlin, sixth C2 domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Ferlin, fifth C2 domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Ferlin, fourth C2 domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Peroxin/Ferlin domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Ferlin B-domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

calcium ion binding

determination method

3 references

metal ion binding

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ESD7

determination method

protein binding

determination method

5 references

14 February 2019

Fam65b is important for formation of the HDAC6-dysferlin protein complex during myogenic cell differentiation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ESD7

determination method

14 February 2019

AHNAK, a novel component of the dysferlin protein complex, redistributes to the cytoplasm with dysferlin during skeletal muscle regeneration

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ESD7

determination method

14 February 2019

Dysferlin Interacts with Annexins A1 and A2 and Mediates Sarcolemmal Wound-healing

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ESD7

determination method

14 February 2019

A New Role for the Muscle Repair Protein Dysferlin in Endothelial Cell Adhesion and Angiogenesis

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ESD7

determination method

14 February 2019

Dysferlin interacts with tubulin and microtubules in mouse skeletal muscle

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ESD7

determination method

phospholipid binding

determination method

3 references

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ESD7

determination method

microtubule binding

determination method

1 reference

14 February 2019

Dysferlin interacts with tubulin and microtubules in mouse skeletal muscle

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ESD7

determination method

integral component of membrane

determination method

2 references

determination method

2 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ESD7

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ESD7

determination method

determination method

2 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ESD7

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ESD7

determination method

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ESD7

determination method

determination method

5 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ESD7

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ESD7

determination method

14 February 2019

Rapid actin-cytoskeleton-dependent recruitment of plasma membrane-derived dysferlin at wounds is critical for muscle membrane repair

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ESD7

determination method

14 February 2019

Aberrant dysferlin trafficking in cells lacking caveolin or expressing dystrophy mutants of caveolin-3

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ESD7

determination method

14 February 2019

Dysferlin stabilizes stress-induced Ca2+ signaling in the transverse tubule membrane

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ESD7

determination method

plasma membrane

determination method

4 references

24 April 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9ESD7&geneProductId=UniProtKB:Q9ESD7

determination method

24 April 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9ESD7&geneProductId=UniProtKB:Q9ESD7

determination method

24 April 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9ESD7&geneProductId=UniProtKB:Q9ESD7

determination method

24 April 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9ESD7&geneProductId=UniProtKB:Q9ESD7

determination method

endocytic vesicle

determination method

2 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ESD7

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ESD7

determination method

determination method

2 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ESD7

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ESD7

determination method

determination method

8 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ESD7

determination method

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ESD7

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ESD7

determination method

14 February 2019

Defective membrane repair in dysferlin-deficient muscular dystrophy

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ESD7

determination method

14 February 2019

Dysferlin Interacts with Annexins A1 and A2 and Mediates Sarcolemmal Wound-healing

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ESD7

determination method

14 February 2019

Aberrant dysferlin trafficking in cells lacking caveolin or expressing dystrophy mutants of caveolin-3

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ESD7

determination method

14 February 2019

A rostrocaudal muscular dystrophy caused by a defect in choline kinase beta, the first enzyme in phosphatidylcholine biosynthesis

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ESD7

determination method

14 February 2019

Rapid actin-cytoskeleton-dependent recruitment of plasma membrane-derived dysferlin at wounds is critical for muscle membrane repair

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ESD7

determination method

cytoplasmic vesicle membrane

determination method

2 references

determination method

1 reference

14 February 2019

Affixin activates Rac1 via betaPIX in C2C12 myoblast

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ESD7

determination method

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ESD7

determination method

determination method

1 reference

14 February 2019

A New Role for the Muscle Repair Protein Dysferlin in Endothelial Cell Adhesion and Angiogenesis

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ESD7

determination method

Golgi apparatus

determination method

1 reference

14 February 2019

A New Role for the Muscle Repair Protein Dysferlin in Endothelial Cell Adhesion and Angiogenesis

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ESD7

determination method

determination method

1 reference

14 February 2019

Dysferlin interacts with tubulin and microtubules in mouse skeletal muscle

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ESD7

determination method

plasma membrane

determination method

6 references

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ESD7

determination method

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ESD7

determination method

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ESD7

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ESD7

determination method

14 February 2019

A New Role for the Muscle Repair Protein Dysferlin in Endothelial Cell Adhesion and Angiogenesis

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ESD7

determination method

14 February 2019

Rapid actin-cytoskeleton-dependent recruitment of plasma membrane-derived dysferlin at wounds is critical for muscle membrane repair

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ESD7

determination method

membrane microdomain

determination method

1 reference

14 February 2019

A New Role for the Muscle Repair Protein Dysferlin in Endothelial Cell Adhesion and Angiogenesis

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ESD7

determination method

biological process

plasma membrane repair

determination method

3 references

14 February 2019

Defective membrane repair in dysferlin-deficient muscular dystrophy

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ESD7

determination method

14 February 2019

Dysferlin Interacts with Annexins A1 and A2 and Mediates Sarcolemmal Wound-healing

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ESD7

determination method

14 February 2019

Rapid actin-cytoskeleton-dependent recruitment of plasma membrane-derived dysferlin at wounds is critical for muscle membrane repair

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ESD7

determination method

determination method

1 reference

14 February 2019

Defective membrane repair in dysferlin-deficient muscular dystrophy

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ESD7

determination method

determination method

1 reference

14 February 2019

A New Role for the Muscle Repair Protein Dysferlin in Endothelial Cell Adhesion and Angiogenesis

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ESD7

determination method

positive regulation of endothelial cell proliferation

determination method

1 reference

14 February 2019

A New Role for the Muscle Repair Protein Dysferlin in Endothelial Cell Adhesion and Angiogenesis

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ESD7

determination method

monocyte activation involved in immune response

determination method

3 references

14 February 2019

Dysferlin deficiency enhances monocyte phagocytosis: a model for the inflammatory onset of limb-girdle muscular dystrophy 2B.

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ESD7

determination method

14 February 2019

Dysferlin deficiency enhances monocyte phagocytosis: a model for the inflammatory onset of limb-girdle muscular dystrophy 2B.

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ESD7

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ESD7

determination method

macrophage activation involved in immune response

determination method

3 references

14 February 2019

Dysferlin deficiency enhances monocyte phagocytosis: a model for the inflammatory onset of limb-girdle muscular dystrophy 2B.

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ESD7

determination method

14 February 2019

Dysferlin deficiency enhances monocyte phagocytosis: a model for the inflammatory onset of limb-girdle muscular dystrophy 2B.

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ESD7

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ESD7

determination method

negative regulation of gene expression

determination method

1 reference

14 February 2019

Dysferlin deficiency enhances monocyte phagocytosis: a model for the inflammatory onset of limb-girdle muscular dystrophy 2B.

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ESD7

determination method

determination method

1 reference

14 February 2019

Lipid accumulation in dysferlin-deficient muscles.

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ESD7

determination method

negative regulation of protein catabolic process

determination method

1 reference

14 February 2019

A New Role for the Muscle Repair Protein Dysferlin in Endothelial Cell Adhesion and Angiogenesis

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ESD7

determination method

skeletal muscle tissue regeneration

determination method

1 reference

14 February 2019

Attenuated muscle regeneration is a key factor in dysferlin-deficient muscular dystrophy

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ESD7

determination method

fat cell differentiation

determination method

1 reference

14 February 2019

Lipid accumulation in dysferlin-deficient muscles.

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ESD7

determination method

positive regulation of cell adhesion

determination method

1 reference

14 February 2019

A New Role for the Muscle Repair Protein Dysferlin in Endothelial Cell Adhesion and Angiogenesis

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ESD7

determination method

negative regulation of phagocytosis

determination method

3 references

14 February 2019

Dysferlin deficiency enhances monocyte phagocytosis: a model for the inflammatory onset of limb-girdle muscular dystrophy 2B.

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ESD7

determination method

14 February 2019

Dysferlin deficiency enhances monocyte phagocytosis: a model for the inflammatory onset of limb-girdle muscular dystrophy 2B.

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ESD7

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ESD7

determination method

cellular response to osmotic stress

determination method

1 reference

14 February 2019

Dysferlin stabilizes stress-induced Ca2+ signaling in the transverse tubule membrane

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ESD7

determination method

positive regulation of neutrophil chemotaxis

determination method

1 reference

14 February 2019

Attenuated muscle regeneration is a key factor in dysferlin-deficient muscular dystrophy

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ESD7

determination method

regulation of calcium ion import

determination method

1 reference

14 February 2019

Dysferlin stabilizes stress-induced Ca2+ signaling in the transverse tubule membrane

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ESD7

determination method

negative regulation of high voltage-gated calcium channel activity

determination method

1 reference

14 February 2019

Dysferlin stabilizes stress-induced Ca2+ signaling in the transverse tubule membrane

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ESD7

determination method

negative regulation of protein polyubiquitination

determination method

1 reference

14 February 2019

A New Role for the Muscle Repair Protein Dysferlin in Endothelial Cell Adhesion and Angiogenesis

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ESD7

determination method

Ferlin B-domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9ESD7

Ferlin, C-terminal domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9ESD7

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9ESD7

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9ESD7

Peroxin/Ferlin domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9ESD7

Ferlin A-domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9ESD7

Ferlin, fifth C2 domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9ESD7

Ferlin, second C2 domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9ESD7

Ferlin, third C2 domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9ESD7

Ferlin, fourth C2 domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9ESD7

Ferlin, first C2 domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9ESD7

Ferlin, sixth C2 domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9ESD7

Identifiers

RefSeq protein ID

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

10 April 2022

1 reference

10 April 2022

1 reference

10 April 2022

1 reference

10 April 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

ENSMUSP00000080579

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000080579

ENSMUSP00000109449

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000109449

ENSMUSP00000132297

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000132297

ENSMUSP00000087022

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000087022

ENSMUSP00000109452

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000109452

ENSMUSP00000109454

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000109454

ENSMUSP00000144705

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000144705

ENSMUSP00000144748

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000144748

ENSMUSP00000144970

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000144970

ENSMUSP00000145292

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000145292

ENSMUSP00000145511

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000145511

ENSMUSP00000145518

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000145518

Sitelinks

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Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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