(Q14887528)

http://www.ebi.ac.uk/interpro/protein/P10810

Monocyte differentiation antigen CD14

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P10810

membrane protein

1 reference

based on heuristic

inferred from GOA cell component → membrane

Leucine-rich repeat, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

lipopolysaccharide binding

3 references

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10810

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10810

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10810

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10810

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10810

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10810

lipopolysaccharide receptor complex

anchored component of external side of plasma membrane

3 references

4 references

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P10810&geneProductId=UniProtKB:P10810

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P10810&geneProductId=UniProtKB:P10810

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P10810&geneProductId=UniProtKB:P10810

16 July 2018

Lipid rafts clustering and signalling by listeriolysin O

http://www.ebi.ac.uk/QuickGO/annotations?protein=P10810&geneProductId=UniProtKB:P10810

anchored component of membrane

IDA

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10810

external side of plasma membrane

1 reference

16 July 2018

Resistance to endotoxin shock and reduced dissemination of gram-negative bacteria in CD14-deficient mice

http://www.ebi.ac.uk/QuickGO/annotations?protein=P10810&geneProductId=UniProtKB:P10810

3 references

3 references

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10810

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10810

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10810

14 February 2019

Lipid rafts clustering and signalling by listeriolysin O

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10810

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10810

lipopolysaccharide receptor complex

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10810

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10810

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10810

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10810

Resistance to endotoxin shock and reduced dissemination of gram-negative bacteria in CD14-deficient mice

biological process

response to bacterium

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P10810&geneProductId=UniProtKB:P10810

toll-like receptor 4 signaling pathway

1 reference

16 July 2018

The attenuated inflammation of MPL is due to the lack of CD14-dependent tight dimerization of the TLR4/MD2 complex at the plasma membrane

http://www.ebi.ac.uk/QuickGO/annotations?protein=P10810&geneProductId=UniProtKB:P10810

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10810

immune system process

1 reference

14 February 2019

cellular response to diacyl bacterial lipopeptide

3 references

positive regulation of interferon-gamma production

1 reference

16 July 2018

The attenuated inflammation of MPL is due to the lack of CD14-dependent tight dimerization of the TLR4/MD2 complex at the plasma membrane

http://www.ebi.ac.uk/QuickGO/annotations?protein=P10810&geneProductId=UniProtKB:P10810

response to magnesium ion

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10810

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10810

response to electrical stimulus

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10810

receptor-mediated endocytosis

1 reference

14 February 2019

CD14 controls the LPS-induced endocytosis of Toll-like receptor 4

GOA

curator

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10810

cellular response to triacyl bacterial lipopeptide

3 references

positive regulation of endocytosis

1 reference

14 February 2019

CD14 controls the LPS-induced endocytosis of Toll-like receptor 4

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10810

response to lipopolysaccharide

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10810

positive regulation of tumor necrosis factor production

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10810

14 February 2019

Resistance to endotoxin shock and reduced dissemination of gram-negative bacteria in CD14-deficient mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10810

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10810

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10810

innate immune response

1 reference

14 February 2019

cellular response to lipopolysaccharide

4 references

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P10810&geneProductId=UniProtKB:P10810

16 July 2018

Resistance to endotoxin shock and reduced dissemination of gram-negative bacteria in CD14-deficient mice

http://www.ebi.ac.uk/QuickGO/annotations?protein=P10810&geneProductId=UniProtKB:P10810

16 July 2018

The attenuated inflammation of MPL is due to the lack of CD14-dependent tight dimerization of the TLR4/MD2 complex at the plasma membrane

http://www.ebi.ac.uk/QuickGO/annotations?protein=P10810&geneProductId=UniProtKB:P10810

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P10810&geneProductId=UniProtKB:P10810

response to molecule of bacterial origin

1 reference

14 February 2019

Lipid rafts clustering and signalling by listeriolysin O

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10810

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10810

lipopolysaccharide-mediated signaling pathway

1 reference

16 July 2018

The attenuated inflammation of MPL is due to the lack of CD14-dependent tight dimerization of the TLR4/MD2 complex at the plasma membrane

http://www.ebi.ac.uk/QuickGO/annotations?protein=P10810&geneProductId=UniProtKB:P10810

inflammatory response

ISO

inflammatory response

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10810

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10810

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10810

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10810

lipopolysaccharide-mediated signaling pathway

positive regulation of interferon-gamma production

toll-like receptor 4 signaling pathway

cellular response to lipopolysaccharide

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10810

14 February 2019

Resistance to endotoxin shock and reduced dissemination of gram-negative bacteria in CD14-deficient mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10810

14 February 2019

The attenuated inflammation of MPL is due to the lack of CD14-dependent tight dimerization of the TLR4/MD2 complex at the plasma membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10810

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10810

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10810

positive regulation of NIK/NF-kappaB signaling

3 references

positive regulation of type I interferon production

1 reference

16 July 2018

CD14 controls the LPS-induced endocytosis of Toll-like receptor 4

GOA

curator

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?protein=P10810&geneProductId=UniProtKB:P10810

1 reference

InterPro Release 71.0