(Q14903577)

Protein kinase-like domain superfamily

1 reference

membrane protein

1 reference

inferred from GOA cell component → membrane

Serine-threonine/tyrosine-protein kinase, catalytic domain, protein family

1 reference

Protein kinase C-like, phorbol ester/diacylglycerol-binding domain, protein family

1 reference

Diacylglycerol/phorbol-ester binding domain, protein family

1 reference

Raf-like Ras-binding domain, protein family

1 reference

Protein kinase domain, protein family

1 reference

Protein kinase, ATP binding site, protein family

1 reference

Serine/threonine-protein kinase, active site, protein family

1 reference

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99N57

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

14 February 2019

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99N57

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99N57

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99N57

protein serine/threonine kinase activity

9 references

14 February 2019

A novel isoform of Vinexin, Vinexin gamma, regulates Sox9 gene expression through activation of MAPK cascade in mouse fetal gonad

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99N57

14 February 2019

Raf-1 sets the threshold of Fas sensitivity by modulating Rok-alpha signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99N57

14 February 2019

G-protein-coupled receptor-mediated activation of rap GTPases: characterization of a novel Galphai regulated pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99N57

14 February 2019

Kinase-dead BRAF and oncogenic RAS cooperate to drive tumor progression through CRAF

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99N57

14 February 2019

Nilotinib and MEK inhibitors induce synthetic lethality through paradoxical activation of RAF in drug-resistant chronic myeloid leukemia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99N57

14 February 2019

ERK and PDE4 cooperate to induce RAF isoform switching in melanoma

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99N57

14 February 2019

Epithelial sodium channel regulated by differential composition of a signaling complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99N57

14 February 2019

Distinct requirement for an intact dimer interface in wild-type, V600E and kinase-dead B-Raf signalling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99N57

14 February 2019

Bioinformatics and cellular signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99N57

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99N57

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99N57

MAP kinase kinase kinase activity

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99N57

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99N57

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99N57

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99N57

mitogen-activated protein kinase kinase binding

protein serine/threonine kinase activity

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99N57

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99N57

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99N57

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99N57

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99N57

14 February 2019

Spatial regulation of Raf kinase signaling by RKTG

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99N57

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99N57

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99N57

3 references

24 April 2018

The ankyrin repeat-containing adaptor protein Tvl-1 is a novel substrate and regulator of Raf-1

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99N57&geneProductId=UniProtKB:Q99N57

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99N57&geneProductId=UniProtKB:Q99N57

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99N57&geneProductId=UniProtKB:Q99N57

1 reference

14 February 2019

A beta-arrestin-dependent scaffold is associated with prolonged MAPK activation in pseudopodia during protease-activated receptor-2-induced chemotaxis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99N57

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99N57

5 references

24 April 2018

The ankyrin repeat-containing adaptor protein Tvl-1 is a novel substrate and regulator of Raf-1

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99N57&geneProductId=UniProtKB:Q99N57

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99N57&geneProductId=UniProtKB:Q99N57

24 April 2018

Spatial regulation of Raf kinase signaling by RKTG

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99N57&geneProductId=UniProtKB:Q99N57

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99N57&geneProductId=UniProtKB:Q99N57

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99N57&geneProductId=UniProtKB:Q99N57

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99N57&geneProductId=UniProtKB:Q99N57

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99N57

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99N57

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99N57

4 references

14 February 2019

The ankyrin repeat-containing adaptor protein Tvl-1 is a novel substrate and regulator of Raf-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99N57

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99N57

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99N57

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99N57

6 references

14 February 2019

The ankyrin repeat-containing adaptor protein Tvl-1 is a novel substrate and regulator of Raf-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99N57

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99N57

14 February 2019

Spatial regulation of Raf kinase signaling by RKTG

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99N57

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99N57

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99N57

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99N57

response to muscle stretch

IBA

biological process

1 reference

14 February 2019

Anisotropic regulation of Ankrd2 gene expression in skeletal muscle by mechanical stretch

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99N57

1 reference

14 February 2019

Overlapping and specific functions of Braf and Craf-1 proto-oncogenes during mouse embryogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99N57

positive regulation of protein phosphorylation

IGI

1 reference

14 February 2019

Pancreatic β-cell Raf-1 is required for glucose tolerance, insulin secretion, and insulin 2 transcription

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99N57

neurotrophin TRK receptor signaling pathway

1 reference

14 February 2019

p21 ras and phosphatidylinositol-3 kinase are required for survival of wild-type and NF1 mutant sensory neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99N57

somatic stem cell population maintenance

1 reference

14 February 2019

B-Raf and C-Raf are required for melanocyte stem cell self-maintenance

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99N57

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99N57

1 reference

14 February 2019

Mouse and human phenotypes indicate a critical conserved role for ERK2 signaling in neural crest development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99N57

cellular glucose homeostasis

IGI

1 reference

14 February 2019

Pancreatic β-cell Raf-1 is required for glucose tolerance, insulin secretion, and insulin 2 transcription

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99N57

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99N57

thyroid gland development

1 reference

14 February 2019

Mouse and human phenotypes indicate a critical conserved role for ERK2 signaling in neural crest development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99N57

1 reference

14 February 2019

Mouse and human phenotypes indicate a critical conserved role for ERK2 signaling in neural crest development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99N57

death-inducing signaling complex assembly

IGI

1 reference

14 February 2019

Raf-1 sets the threshold of Fas sensitivity by modulating Rok-alpha signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99N57

intermediate filament cytoskeleton organization

1 reference

14 February 2019

Raf-1 sets the threshold of Fas sensitivity by modulating Rok-alpha signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99N57

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99N57

positive regulation of transcription by RNA polymerase II

1 reference

14 February 2019

Pancreatic β-cell Raf-1 is required for glucose tolerance, insulin secretion, and insulin 2 transcription

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99N57

insulin secretion involved in cellular response to glucose stimulus

1 reference

14 February 2019

Pancreatic β-cell Raf-1 is required for glucose tolerance, insulin secretion, and insulin 2 transcription

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99N57

positive regulation of ERK1 and ERK2 cascade

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99N57&geneProductId=UniProtKB:Q99N57

3 references

diacylglycerol/phorbol-ester binding

1 reference

Raf-like Ras-binding

1 reference

serine/threonine-protein kinase, active site

1 reference

serine-threonine/tyrosine-protein kinase, catalytic domain

1 reference

protein kinase, ATP binding site

1 reference

protein kinase C-like, phorbol ester/diacylglycerol-binding domain

1 reference

protein kinase domain

1 reference