(Q14906114)

English

Desmoplakin

mammalian protein found in Mus musculus

Dsp
desmoplakin I/II
uniprot:E9Q557
desmoplakin
desmosomal cytoskeletal connector molecule

In more languages

Statements

1 reference

25 May 2022

UniProt protein ID

Plakin repeat superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/E9Q557

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/E9Q557

membrane protein

1 reference

based on heuristic

inferred from GOA cell component → membrane

SH3 domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Plectin repeat, protein family

1 reference

based on heuristic

inferred from protein domain or family

Spectrin/alpha-actinin, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

protein binding

determination method

cell adhesion molecule binding

determination method

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q557

determination method

structural molecule activity

determination method

3 references

determination method

1 reference

24 April 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=E9Q557&geneProductId=UniProtKB:E9Q557

determination method

intercalated disc

determination method

4 references

24 April 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=E9Q557&geneProductId=UniProtKB:E9Q557

determination method

24 April 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=E9Q557&geneProductId=UniProtKB:E9Q557

determination method

24 April 2018

Evolutionarily conserved intercalated disc protein Tmem65 regulates cardiac conduction and connexin 43 function

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=E9Q557&geneProductId=UniProtKB:E9Q557

determination method

24 April 2018

A unique and specific interaction between alphaT-catenin and plakophilin-2 in the area composita, the mixed-type junctional structure of cardiac intercalated discs

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=E9Q557&geneProductId=UniProtKB:E9Q557

determination method

plasma membrane

determination method

4 references

24 April 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=E9Q557&geneProductId=UniProtKB:E9Q557

determination method

24 April 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=E9Q557&geneProductId=UniProtKB:E9Q557

determination method

24 April 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=E9Q557&geneProductId=UniProtKB:E9Q557

determination method

24 April 2018

Evolutionarily conserved intercalated disc protein Tmem65 regulates cardiac conduction and connexin 43 function

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=E9Q557&geneProductId=UniProtKB:E9Q557

determination method

determination method

2 references

basolateral plasma membrane

determination method

1 reference

14 February 2019

Expressions of hepatobiliary organic anion transporters and bilirubin-conjugating enzyme in differentiating embryonic stem cells

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q557

determination method

determination method

2 references

intermediate filament

determination method

1 reference

24 April 2018

Desmosomal dysfunction due to mutations in desmoplakin causes arrhythmogenic right ventricular dysplasia/cardiomyopathy

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=E9Q557&geneProductId=UniProtKB:E9Q557

determination method

fascia adherens

determination method

2 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q557

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q557

determination method

determination method

7 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q557

determination method

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q557

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q557

determination method

14 February 2019

Epiplakin attenuates experimental mouse liver injury by chaperoning keratin reorganization

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q557

determination method

14 February 2019

Plakoglobin is required for effective intermediate filament anchorage to desmosomes

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q557

determination method

14 February 2019

Desmocollin 3 is required for pre-implantation development of the mouse embryo

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q557

determination method

14 February 2019

Assessment of splice variant-specific functions of desmocollin 1 in the skin

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q557

determination method

plasma membrane

determination method

5 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q557

determination method

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q557

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q557

determination method

14 February 2019

Evolutionarily conserved intercalated disc protein Tmem65 regulates cardiac conduction and connexin 43 function

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q557

determination method

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q557

determination method

intercalated disc

determination method

5 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q557

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q557

determination method

14 February 2019

Evolutionarily conserved intercalated disc protein Tmem65 regulates cardiac conduction and connexin 43 function

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q557

determination method

14 February 2019

A unique and specific interaction between alphaT-catenin and plakophilin-2 in the area composita, the mixed-type junctional structure of cardiac intercalated discs

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q557

determination method

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q557

determination method

determination method

3 references

14 February 2019

Activator of G protein signaling 8 (AGS8) is required for hypoxia-induced apoptosis of cardiomyocytes: role of G betagamma and connexin 43 (CX43)

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q557

determination method

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q557

determination method

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q557

determination method

biological process

intermediate filament organization

determination method

1 reference

14 February 2019

Desmosomal dysfunction due to mutations in desmoplakin causes arrhythmogenic right ventricular dysplasia/cardiomyopathy

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q557

determination method

ventricular compact myocardium morphogenesis

determination method

1 reference

14 February 2019

Desmosomal dysfunction due to mutations in desmoplakin causes arrhythmogenic right ventricular dysplasia/cardiomyopathy

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q557

determination method

determination method

1 reference

24 April 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=E9Q557&geneProductId=UniProtKB:E9Q557

determination method

protein localization to adherens junction

determination method

1 reference

14 February 2019

Desmosomal dysfunction due to mutations in desmoplakin causes arrhythmogenic right ventricular dysplasia/cardiomyopathy

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q557

determination method

intermediate filament cytoskeleton organization

determination method

1 reference

24 April 2018

Desmoplakin is required early in development for assembly of desmosomes and cytoskeletal linkage

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=E9Q557&geneProductId=UniProtKB:E9Q557

determination method

adherens junction organization

determination method

1 reference

14 February 2019

Desmoplakin is essential in epidermal sheet formation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q557

determination method

skin development

determination method

1 reference

24 April 2018

Desmoplakin is essential in epidermal sheet formation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=E9Q557&geneProductId=UniProtKB:E9Q557

determination method

cell-cell adhesion

determination method

3 references

24 April 2018

Desmoplakin is essential in epidermal sheet formation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=E9Q557&geneProductId=UniProtKB:E9Q557

determination method

24 April 2018

Desmoplakin is required early in development for assembly of desmosomes and cytoskeletal linkage

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=E9Q557&geneProductId=UniProtKB:E9Q557

determination method

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=E9Q557&geneProductId=UniProtKB:E9Q557

determination method

cell-cell adhesion

determination method

4 references

14 February 2019

Desmoplakin is essential in epidermal sheet formation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q557

determination method

14 February 2019

Desmoplakin is required early in development for assembly of desmosomes and cytoskeletal linkage

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q557

determination method

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q557

determination method

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q557

determination method

Spectrin/alpha-actinin

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/E9Q557

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/E9Q557

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/E9Q557

Identifiers

RefSeq protein ID

1 reference

20 March 2022

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

ENSMUSP00000115062

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000115062

ENSMUSP00000117252

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000117252

Sitelinks

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Multilingual sites(0 entries)

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