(Q14907610)

membrane protein

1 reference

inferred from GOA cell component → membrane

Tyrosine-protein kinase ephrin type A/B receptor-like, protein family

1 reference

inferred from protein domain or family

TNFR/NGFR cysteine-rich region, protein family

1 reference

inferred from protein domain or family

Tumour necrosis factor receptor 4, N-terminal domain, protein family

1 reference

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

4 references

24 April 2018

4-1BB and Ox40 are members of a tumor necrosis factor (TNF)-nerve growth factor receptor subfamily that bind TNF receptor-associated factors and activate nuclear factor kappaB

http://www.ebi.ac.uk/QuickGO/annotations?protein=P47741&geneProductId=UniProtKB:P47741

24 April 2018

Antigen-independent signalosome of CARMA1, PKCθ, and TNF receptor-associated factor 2 (TRAF2) determines NF-κB signaling in T cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P47741&geneProductId=UniProtKB:P47741

24 April 2018

GITR interacts with the pro-apoptotic protein Siva and induces apoptosis

HUGO Gene Nomenclature Committee

http://www.ebi.ac.uk/QuickGO/annotations?protein=P47741&geneProductId=UniProtKB:P47741

24 April 2018

Cross-linking of OX40 ligand, a member of the TNF/NGF cytokine family, induces proliferation and differentiation in murine splenic B cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P47741&geneProductId=UniProtKB:P47741

tumor necrosis factor-activated receptor activity

IPI

1 reference

24 April 2018

OX40/OX40L interaction induces the expression of CXCR5 and contributes to chronic colitis induced by dextran sulfate sodium in mice

http://www.ebi.ac.uk/QuickGO/annotations?protein=P47741&geneProductId=UniProtKB:P47741

tumor necrosis factor-activated receptor activity

IPI

5 references

14 February 2019

4-1BB and Ox40 are members of a tumor necrosis factor (TNF)-nerve growth factor receptor subfamily that bind TNF receptor-associated factors and activate nuclear factor kappaB

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47741

14 February 2019

Antigen-independent signalosome of CARMA1, PKCθ, and TNF receptor-associated factor 2 (TRAF2) determines NF-κB signaling in T cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47741

14 February 2019

GITR interacts with the pro-apoptotic protein Siva and induces apoptosis

HUGO Gene Nomenclature Committee

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47741

14 February 2019

Cross-linking of OX40 ligand, a member of the TNF/NGF cytokine family, induces proliferation and differentiation in murine splenic B cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47741

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47741

integral component of membrane

cell component

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47741

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47741

1 reference

14 February 2019

Robust B cell immunity but impaired T cell proliferation in the absence of CD134 (OX40)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47741

integral component of plasma membrane

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P47741&geneProductId=UniProtKB:P47741

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47741

external side of plasma membrane

ISO

3 references

14 February 2019

Increased Foxp3(+) CD4(+) regulatory T cells with intact suppressive activity but altered cellular localization in murine lupus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47741

14 February 2019

Where CD4+CD25+ T reg cells impinge on autoimmune diabetes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47741

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47741

regulation of apoptotic process

biological process

1 reference

14 February 2019

The costimulation-regulated duration of PKB activation controls T cell longevity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47741

negative regulation of activation-induced cell death of T cells

1 reference

24 April 2018

OX40 promotes Bcl-xL and Bcl-2 expression and is essential for long-term survival of CD4 T cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P47741&geneProductId=UniProtKB:P47741

negative regulation of extrinsic apoptotic signaling pathway

1 reference

24 April 2018

OX40 promotes Bcl-xL and Bcl-2 expression and is essential for long-term survival of CD4 T cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P47741&geneProductId=UniProtKB:P47741

negative regulation of DNA-binding transcription factor activity

1 reference

24 April 2018

Cross-linking of OX40 ligand, a member of the TNF/NGF cytokine family, induces proliferation and differentiation in murine splenic B cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P47741&geneProductId=UniProtKB:P47741

multicellular organism development

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P47741&geneProductId=UniProtKB:P47741

cellular defense response

1 reference

24 April 2018

Robust B cell immunity but impaired T cell proliferation in the absence of CD134 (OX40)

http://www.ebi.ac.uk/QuickGO/annotations?protein=P47741&geneProductId=UniProtKB:P47741

response to lipopolysaccharide

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P47741&geneProductId=UniProtKB:P47741

positive regulation of B cell proliferation

1 reference

24 April 2018

Cross-linking of OX40 ligand, a member of the TNF/NGF cytokine family, induces proliferation and differentiation in murine splenic B cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P47741&geneProductId=UniProtKB:P47741

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P47741&geneProductId=UniProtKB:P47741

regulation of protein kinase activity

1 reference

24 April 2018

The costimulation-regulated duration of PKB activation controls T cell longevity

http://www.ebi.ac.uk/QuickGO/annotations?protein=P47741&geneProductId=UniProtKB:P47741

inflammatory response

negative regulation of transcription, DNA-templated

IPI

1 reference

24 April 2018

Cross-linking of OX40 ligand, a member of the TNF/NGF cytokine family, induces proliferation and differentiation in murine splenic B cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P47741&geneProductId=UniProtKB:P47741

tumor necrosis factor-mediated signaling pathway

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47741

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P47741&geneProductId=UniProtKB:P47741

OX40/OX40L interaction induces the expression of CXCR5 and contributes to chronic colitis induced by dextran sulfate sodium in mice

ISO

inflammatory response

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47741

14 February 2019

The costimulation-regulated duration of PKB activation controls T cell longevity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47741

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47741

positive regulation of B cell proliferation

negative regulation of DNA-binding transcription factor activity

negative regulation of transcription, DNA-templated

TNFR/NGFR cysteine-rich region

1 reference

tyrosine-protein kinase ephrin type A/B receptor-like

1 reference

Tumour necrosis factor receptor 4, N-terminal

1 reference