(Q14907950)

Immunoglobulin-like domain superfamily

1 reference

inferred from GOA cell component → membrane

membrane protein

1 reference

based on heuristic

Immunoglobulin subtype, protein family

1 reference

based on heuristic

inferred from protein domain or family

immunoglobulin-like domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

9 May 2019

B cell activation involves nanoscale receptor reorganizations and inside-out signaling by Syk

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25918

integral component of membrane

IPI

cell component

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25918

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25918

external side of plasma membrane

11 references

27 March 2018

FcRL6, a new ITIM-bearing receptor on cytolytic cells, is broadly expressed by lymphocytes following HIV-1 infection

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25918&geneProductId=UniProtKB:P25918

27 March 2018

MicroRNAs enriched in hematopoietic stem cells differentially regulate long-term hematopoietic output

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25918&geneProductId=UniProtKB:P25918

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25918&geneProductId=UniProtKB:P25918

27 March 2018

Missing self-recognition of Ocil/Clr-b by inhibitory NKR-P1 natural killer cell receptors

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25918&geneProductId=UniProtKB:P25918

27 March 2018

M17, a gene specific for germinal center (GC) B cells and a prognostic marker for GC B-cell lymphomas, is dispensable for the GC reaction in mice

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25918&geneProductId=UniProtKB:P25918

27 March 2018

Both the pre-BCR and the IL-7Ralpha are essential for expansion at the pre-BII cell stage in vivo

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25918&geneProductId=UniProtKB:P25918

27 March 2018

T-bet regulates T-independent IgG2a class switching

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25918&geneProductId=UniProtKB:P25918

27 March 2018

A complementary role for the tetraspanins CD37 and Tssc6 in cellular immunity

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25918&geneProductId=UniProtKB:P25918

27 March 2018

The selection of marginal zone B cells differs from that of B-1a cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25918&geneProductId=UniProtKB:P25918

27 March 2018

BAFF binding to T cell-expressed BAFF-R costimulates T cell proliferation and alloresponses

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25918&geneProductId=UniProtKB:P25918

27 March 2018

GATA-3 regulates the development and function of invariant NKT cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25918&geneProductId=UniProtKB:P25918

external side of plasma membrane

IDA

12 references

9 May 2019

MicroRNAs enriched in hematopoietic stem cells differentially regulate long-term hematopoietic output

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25918

9 May 2019

FcRL6, a new ITIM-bearing receptor on cytolytic cells, is broadly expressed by lymphocytes following HIV-1 infection

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25918

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25918

9 May 2019

Missing self-recognition of Ocil/Clr-b by inhibitory NKR-P1 natural killer cell receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25918

9 May 2019

T-bet regulates T-independent IgG2a class switching

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25918

9 May 2019

GATA-3 regulates the development and function of invariant NKT cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25918

9 May 2019

BAFF binding to T cell-expressed BAFF-R costimulates T cell proliferation and alloresponses

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25918

9 May 2019

M17, a gene specific for germinal center (GC) B cells and a prognostic marker for GC B-cell lymphomas, is dispensable for the GC reaction in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25918

9 May 2019

The selection of marginal zone B cells differs from that of B-1a cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25918

9 May 2019

A complementary role for the tetraspanins CD37 and Tssc6 in cellular immunity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25918

9 May 2019

Both the pre-BCR and the IL-7Ralpha are essential for expansion at the pre-BII cell stage in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25918

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25918

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25918&geneProductId=UniProtKB:P25918

integral component of plasma membrane

TAS

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25918

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25918

9 May 2019

Impairment of T-cell-dependent B-cell responses and B-1 cell development in CD19-deficient mice.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25918

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25918

B cell receptor signaling pathway

biological process

1 reference

27 March 2018

The motheaten mutation rescues B cell signaling and development in CD45-deficient mice

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25918&geneProductId=UniProtKB:P25918

cellular defense response

IDA

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25918&geneProductId=UniProtKB:P25918

positive regulation of release of sequestered calcium ion into cytosol

IBA

1 reference

11 October 2018

c-Abl-deficient mice exhibit reduced numbers of peritoneal B-1 cells and defects in BCR-induced B cell activation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25918&geneProductId=UniProtKB:P25918

B-1 B cell differentiation

IGI

1 reference

9 May 2019

Impairment of T-cell-dependent B-cell responses and B-1 cell development in CD19-deficient mice.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25918

Impairment of T-cell-dependent B-cell responses and B-1 cell development in CD19-deficient mice.

IMP

B cell mediated immunity

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25918

positive regulation of phosphatidylinositol 3-kinase activity

IMP

3 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25918&geneProductId=UniProtKB:P25918

1 January 2018

Qualitative regulation of B cell antigen receptor signaling by CD19: selective requirement for PI3-kinase activation, inositol-1,4,5-trisphosphate production and Ca2+ mobilization

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25918&geneProductId=UniProtKB:P25918

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25918&geneProductId=UniProtKB:P25918

regulation of B cell receptor signaling pathway

3 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25918&geneProductId=UniProtKB:P25918

1 January 2018

Qualitative regulation of B cell antigen receptor signaling by CD19: selective requirement for PI3-kinase activation, inositol-1,4,5-trisphosphate production and Ca2+ mobilization

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25918&geneProductId=UniProtKB:P25918

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25918&geneProductId=UniProtKB:P25918

positive regulation of release of sequestered calcium ion into cytosol

4 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25918&geneProductId=UniProtKB:P25918

1 January 2018

Qualitative regulation of B cell antigen receptor signaling by CD19: selective requirement for PI3-kinase activation, inositol-1,4,5-trisphosphate production and Ca2+ mobilization

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25918&geneProductId=UniProtKB:P25918

1 January 2018

c-Abl-deficient mice exhibit reduced numbers of peritoneal B-1 cells and defects in BCR-induced B cell activation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25918&geneProductId=UniProtKB:P25918

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25918&geneProductId=UniProtKB:P25918

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25918

adaptive immune response

1 reference

9 May 2019

B cell proliferation involved in immune response

immune system process

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25918

immunoglobulin mediated immune response

positive regulation of phosphatidylinositol 3-kinase activity

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25918

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25918

9 May 2019

Qualitative regulation of B cell antigen receptor signaling by CD19: selective requirement for PI3-kinase activation, inositol-1,4,5-trisphosphate production and Ca2+ mobilization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25918

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25918

antigen receptor-mediated signaling pathway

regulation of B cell receptor signaling pathway

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25918

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25918

9 May 2019

Qualitative regulation of B cell antigen receptor signaling by CD19: selective requirement for PI3-kinase activation, inositol-1,4,5-trisphosphate production and Ca2+ mobilization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25918

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25918

regulation of B cell activation

positive regulation of release of sequestered calcium ion into cytosol

5 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25918

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25918

9 May 2019

Qualitative regulation of B cell antigen receptor signaling by CD19: selective requirement for PI3-kinase activation, inositol-1,4,5-trisphosphate production and Ca2+ mobilization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25918

9 May 2019

c-Abl-deficient mice exhibit reduced numbers of peritoneal B-1 cells and defects in BCR-induced B cell activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25918

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25918

B cell receptor signaling pathway

3 references

9 May 2019

The Actin and Tetraspanin Networks Organize Receptor Nanoclusters to Regulate B Cell Receptor-Mediated Signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25918

9 May 2019

The motheaten mutation rescues B cell signaling and development in CD45-deficient mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25918

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25918

IBA

has part(s)

immunoglobulin subtype

1 reference

immunoglobulin-like domain

1 reference