(Q14911646)

Protein kinase-like domain superfamily

1 reference

Immunoglobulin-like domain superfamily

1 reference

fibroblast growth factor receptor family

1 reference

membrane protein

1 reference

inferred from GOA cell component → membrane

Immunoglobulin I-set, protein family

1 reference

Serine-threonine/tyrosine-protein kinase, catalytic domain, protein family

1 reference

Immunoglobulin subtype, protein family

1 reference

Immunoglobulin subtype 2, protein family

1 reference

Protein kinase domain, protein family

1 reference

immunoglobulin-like domain, protein family

1 reference

Protein kinase, ATP binding site, protein family

1 reference

Tyrosine-protein kinase, catalytic domain, protein family

1 reference

Tyrosine-protein kinase, active site, protein family

1 reference

1 reference

25 May 2022

1 reference

25 May 2022

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

1 reference

9 May 2019

kinase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

1 reference

9 May 2019

transmembrane receptor protein tyrosine kinase activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=P21803&geneProductId=UniProtKB:P21803

1 reference

24 April 2018

protein kinase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

1 reference

9 May 2019

transferase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

1 reference

9 May 2019

protein homodimerization activity

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

protein binding

4 references

9 May 2019

Crkl deficiency disrupts Fgf8 signaling in a mouse model of 22q11 deletion syndromes.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

9 May 2019

Regulation of fibroblast growth factor-23 signaling by klotho

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

9 May 2019

Developmental localization of the splicing alternatives of fibroblast growth factor receptor-2 (FGFR2)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

9 May 2019

Co-localization of neural cell adhesion molecule and fibroblast growth factor receptor 2 in early embryo development

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

nucleotide binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

1 reference

9 May 2019

identical protein binding

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

transmembrane signaling receptor activity

1 reference

7 November 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P21803&geneProductId=UniProtKB:P21803

fibroblast growth factor-activated receptor activity

fibroblast growth factor binding

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

9 May 2019

Fibroblast growth factor receptor 2 (FGFR2)-mediated reciprocal regulation loop between FGF8 and FGF10 is essential for limb induction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

cell component

cytoplasm

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

1 reference

9 May 2019

nucleus

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

9 May 2019

Fgf9 induces proliferation and nuclear localization of FGFR2 in Sertoli precursors during male sex determination

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

9 May 2019

Foxl2 is required for commitment to ovary differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

cell surface

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

Golgi apparatus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

1 reference

9 May 2019

intracellular membrane-bounded organelle

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

extracellular matrix

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P21803&geneProductId=UniProtKB:P21803

plasma membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

1 reference

9 May 2019

nucleoplasm

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

cell cortex

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

integral component of plasma membrane

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P21803&geneProductId=UniProtKB:P21803

excitatory synapse

1 reference

9 May 2019

Fgfr2 is required for the development of the medial prefrontal cortex and its connections with limbic circuits

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

cytoplasmic vesicle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

1 reference

9 May 2019

receptor complex

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

collagen-containing extracellular matrix

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development

biological process

1 reference

9 May 2019

Fgfr2 is required for the development of the medial prefrontal cortex and its connections with limbic circuits

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

ureteric bud development

1 reference

9 May 2019

Role of fibroblast growth factor receptors 1 and 2 in the metanephric mesenchyme

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

organ growth

1 reference

9 May 2019

Stomach development is dependent on fibroblast growth factor 10/fibroblast growth factor receptor 2b-mediated signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

embryonic pattern specification

1 reference

9 May 2019

Stomach development is dependent on fibroblast growth factor 10/fibroblast growth factor receptor 2b-mediated signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

bud elongation involved in lung branching

1 reference

9 May 2019

Levels of mesenchymal FGFR2 signaling modulate smooth muscle progenitor cell commitment in the lung

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

positive regulation of canonical Wnt signaling pathway

membranous septum morphogenesis

1 reference

9 May 2019

Congenital heart defects in Fgfr2-IIIb and Fgf10 mutant mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow

1 reference

9 May 2019

Signaling from fibroblast growth factor receptor 2 in immature hematopoietic cells facilitates donor hematopoiesis after intra-bone marrow-bone marrow transplantation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

embryonic organ morphogenesis

1 reference

9 May 2019

Development of the mammalian urethra is controlled by Fgfr2-IIIb

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

post-embryonic development

1 reference

9 May 2019

Levels of mesenchymal FGFR2 signaling modulate smooth muscle progenitor cell commitment in the lung

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

squamous basal epithelial stem cell differentiation involved in prostate gland acinus development

1 reference

9 May 2019

Fibroblast growth factor receptor 2 tyrosine kinase is required for prostatic morphogenesis and the acquisition of strict androgen dependency for adult tissue homeostasis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

branching morphogenesis of a nerve

1 reference

9 May 2019

Fgfr2b mediated epithelial-mesenchymal interactions coordinate tooth morphogenesis and dental trigeminal axon patterning

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

reproductive structure development

1 reference

9 May 2019

Spontaneous mutation in mice provides new insight into the genetic mechanisms that pattern the seminal vesicles and prostate gland

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell

1 reference

9 May 2019

Signaling from fibroblast growth factor receptor 2 in immature hematopoietic cells facilitates donor hematopoiesis after intra-bone marrow-bone marrow transplantation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

ventricular cardiac muscle tissue morphogenesis

1 reference

9 May 2019

Congenital heart defects in Fgfr2-IIIb and Fgf10 mutant mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

protein phosphorylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

1 reference

9 May 2019

positive regulation of cardiac muscle cell proliferation

1 reference

9 May 2019

Endocardial and epicardial derived FGF signals regulate myocardial proliferation and differentiation in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

mesenchymal cell differentiation

1 reference

9 May 2019

Role of fibroblast growth factor receptors 1 and 2 in the metanephric mesenchyme

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

positive regulation of mesenchymal cell proliferation

1 reference

9 May 2019

FGF9 and SHH signaling coordinate lung growth and development through regulation of distinct mesenchymal domains

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

neuromuscular junction development

1 reference

9 May 2019

Distinct target-derived signals organize formation, maturation, and maintenance of motor nerve terminals

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

negative regulation of mitotic nuclear division

1 reference

9 May 2019

Fibroblast growth factor receptor signaling is essential for lens fiber cell differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis

1 reference

9 May 2019

Fibroblast growth factor receptor 2 tyrosine kinase is required for prostatic morphogenesis and the acquisition of strict androgen dependency for adult tissue homeostasis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

angiogenesis

1 reference

9 May 2019

Fibroblast growth factor signals regulate a wave of Hedgehog activation that is essential for coronary vascular development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

prostate gland morphogenesis

1 reference

9 May 2019

Role of epithelial cell fibroblast growth factor receptor substrate 2alpha in prostate development, regeneration and tumorigenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

positive regulation of ERK1 and ERK2 cascade

1 reference

9 May 2019

The mouse seminal vesicle shape mutation is allelic with Fgfr2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

orbitofrontal cortex development

1 reference

9 May 2019

Fgfr2 is required for the development of the medial prefrontal cortex and its connections with limbic circuits

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

animal organ morphogenesis

1 reference

9 May 2019

Spontaneous mutation in mice provides new insight into the genetic mechanisms that pattern the seminal vesicles and prostate gland

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

embryonic digestive tract morphogenesis

3 references

9 May 2019

Stomach development is dependent on fibroblast growth factor 10/fibroblast growth factor receptor 2b-mediated signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

9 May 2019

Pitx2 is a critical early regulatory gene in normal cecal development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

9 May 2019

Retinaldehyde dehydrogenase 2 is down-regulated during duodenal atresia formation in Fgfr2IIIb-/- mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

hair follicle morphogenesis

1 reference

9 May 2019

A crucial role for Fgfr2-IIIb signalling in epidermal development and hair follicle patterning

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

morphogenesis of embryonic epithelium

1 reference

9 May 2019

Development of the mammalian urethra is controlled by Fgfr2-IIIb

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

vasculogenesis involved in coronary vascular morphogenesis

TAS

1 reference

9 May 2019

Epicardial-myocardial signaling directing coronary vasculogenesis

Developmental FunctionaL Annotation at Tufts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

negative regulation of cell population proliferation

TAS

1 reference

9 May 2019

Fibroblast growth factor receptor signaling is essential for lens fiber cell differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

branch elongation involved in salivary gland morphogenesis

apoptotic process

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

1 reference

9 May 2019

branching involved in salivary gland morphogenesis

1 reference

9 May 2019

Embryonic submandibular gland morphogenesis: stage-specific protein localization of FGFs, BMPs, Pax6 and Pax9 in normal mice and abnormal SMG phenotypes in FgfR2-IIIc(+/Delta), BMP7(-/-) and Pax6(-/-) mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

cell fate commitment

1 reference

14 February 2019

Fibroblast growth factor receptor signaling promotes radial glial identity and interacts with Notch1 signaling in telencephalic progenitors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

coronal suture morphogenesis

1 reference

9 May 2019

Early onset of craniosynostosis in an Apert mouse model reveals critical features of this pathology

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

embryonic organ development

1 reference

9 May 2019

Fibroblast growth factor receptor 2 (FGFR2)-mediated reciprocal regulation loop between FGF8 and FGF10 is essential for limb induction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

endodermal digestive tract morphogenesis

1 reference

9 May 2019

Pitx2 is a critical early regulatory gene in normal cecal development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

fibroblast growth factor receptor signaling pathway involved in hemopoiesis

1 reference

9 May 2019

Signaling from fibroblast growth factor receptor 2 in immature hematopoietic cells facilitates donor hematopoiesis after intra-bone marrow-bone marrow transplantation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

in utero embryonic development

lateral sprouting from an epithelium

1 reference

9 May 2019

Spontaneous mutation in mice provides new insight into the genetic mechanisms that pattern the seminal vesicles and prostate gland

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

positive regulation of Wnt signaling pathway

1 reference

9 May 2019

Levels of mesenchymal FGFR2 signaling modulate smooth muscle progenitor cell commitment in the lung

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

gland morphogenesis

1 reference

9 May 2019

The mouse seminal vesicle shape mutation is allelic with Fgfr2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

positive regulation of cell cycle

1 reference

9 May 2019

Fgfr2 is required for the development of the medial prefrontal cortex and its connections with limbic circuits

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

branching involved in labyrinthine layer morphogenesis

1 reference

9 May 2019

Fibroblast growth factor receptor 2 (FGFR2)-mediated reciprocal regulation loop between FGF8 and FGF10 is essential for limb induction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

branching involved in prostate gland morphogenesis

3 references

9 May 2019

Fibroblast growth factor receptor 2 tyrosine kinase is required for prostatic morphogenesis and the acquisition of strict androgen dependency for adult tissue homeostasis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

9 May 2019

Spontaneous mutation in mice provides new insight into the genetic mechanisms that pattern the seminal vesicles and prostate gland

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

9 May 2019

The mouse seminal vesicle shape mutation is allelic with Fgfr2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

regulation of ERK1 and ERK2 cascade

1 reference

9 May 2019

Levels of mesenchymal FGFR2 signaling modulate smooth muscle progenitor cell commitment in the lung

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

protein autophosphorylation

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

mammary gland bud formation

1 reference

9 May 2019

Role of FGF10/FGFR2b signaling during mammary gland development in the mouse embryo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

pyramidal neuron development

1 reference

9 May 2019

Fgfr2 is required for the development of the medial prefrontal cortex and its connections with limbic circuits

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

lacrimal gland development

1 reference

9 May 2019

FGF10 is an inducer and Pax6 a competence factor for lacrimal gland development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

positive regulation of MAPK cascade

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

regulation of smooth muscle cell differentiation

1 reference

9 May 2019

Levels of mesenchymal FGFR2 signaling modulate smooth muscle progenitor cell commitment in the lung

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

regulation of cell fate commitment

1 reference

14 February 2019

Levels of mesenchymal FGFR2 signaling modulate smooth muscle progenitor cell commitment in the lung

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

bone mineralization

1 reference

9 May 2019

Conditional inactivation of FGF receptor 2 reveals an essential role for FGF signaling in the regulation of osteoblast function and bone growth

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

regulation of branching involved in prostate gland morphogenesis

1 reference

14 February 2019

The mouse seminal vesicle shape mutation is allelic with Fgfr2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

positive regulation of epithelial cell proliferation involved in lung morphogenesis

1 reference

9 May 2019

Levels of mesenchymal FGFR2 signaling modulate smooth muscle progenitor cell commitment in the lung

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

epithelial cell differentiation

1 reference

9 May 2019

Stomach development is dependent on fibroblast growth factor 10/fibroblast growth factor receptor 2b-mediated signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

phosphorylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

1 reference

9 May 2019

multicellular organism growth

1 reference

14 February 2019

Levels of mesenchymal FGFR2 signaling modulate smooth muscle progenitor cell commitment in the lung

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

positive regulation of epithelial cell proliferation

1 reference

14 February 2019

FGF10/FGFR2b signaling plays essential roles during in vivo embryonic submandibular salivary gland morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

ventricular zone neuroblast division

1 reference

9 May 2019

Fgfr2 is required for the development of the medial prefrontal cortex and its connections with limbic circuits

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

epidermis morphogenesis

1 reference

9 May 2019

A crucial role for Fgfr2-IIIb signalling in epidermal development and hair follicle patterning

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

regulation of morphogenesis of a branching structure

1 reference

9 May 2019

The mouse seminal vesicle shape mutation is allelic with Fgfr2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

negative regulation of transcription by RNA polymerase II

1 reference

9 May 2019

Levels of mesenchymal FGFR2 signaling modulate smooth muscle progenitor cell commitment in the lung

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

outflow tract septum morphogenesis

1 reference

9 May 2019

Congenital heart defects in Fgfr2-IIIb and Fgf10 mutant mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

odontogenesis

1 reference

9 May 2019

Fgfr2b mediated epithelial-mesenchymal interactions coordinate tooth morphogenesis and dental trigeminal axon patterning

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

lung alveolus development

lung lobe morphogenesis

1 reference

9 May 2019

Levels of mesenchymal FGFR2 signaling modulate smooth muscle progenitor cell commitment in the lung

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

midbrain development

1 reference

9 May 2019

Fibroblast growth factor receptors cooperate to regulate neural progenitor properties in the developing midbrain and hindbrain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

fibroblast growth factor receptor signaling pathway involved in mammary gland specification

1 reference

9 May 2019

Gli3-mediated somitic Fgf10 expression gradients are required for the induction and patterning of mammary epithelium along the embryonic axes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

mesenchymal cell proliferation involved in lung development

1 reference

9 May 2019

Levels of mesenchymal FGFR2 signaling modulate smooth muscle progenitor cell commitment in the lung

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

prostate epithelial cord elongation

1 reference

9 May 2019

Fibroblast growth factor receptor 2 tyrosine kinase is required for prostatic morphogenesis and the acquisition of strict androgen dependency for adult tissue homeostasis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

mesenchymal cell differentiation involved in lung development

1 reference

9 May 2019

Levels of mesenchymal FGFR2 signaling modulate smooth muscle progenitor cell commitment in the lung

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

axonogenesis

1 reference

9 May 2019

Fgfr2b mediated epithelial-mesenchymal interactions coordinate tooth morphogenesis and dental trigeminal axon patterning

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

regulation of multicellular organism growth

1 reference

14 February 2019

Fibroblast growth factor receptor 2 (FGFR2)-mediated reciprocal regulation loop between FGF8 and FGF10 is essential for limb induction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

epithelial cell proliferation involved in salivary gland morphogenesis

cell-cell signaling

1 reference

9 May 2019

Disruption of Fgf10/Fgfr2b-coordinated epithelial-mesenchymal interactions causes cleft palate

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

regulation of fibroblast growth factor receptor signaling pathway

1 reference

14 February 2019

Levels of mesenchymal FGFR2 signaling modulate smooth muscle progenitor cell commitment in the lung

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

bone morphogenesis

1 reference

9 May 2019

Fgfr2 is required for limb outgrowth and lung-branching morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

positive regulation of phospholipase activity

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

fibroblast growth factor receptor signaling pathway

9 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

9 May 2019

Levels of mesenchymal FGFR2 signaling modulate smooth muscle progenitor cell commitment in the lung

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

9 May 2019

Fibroblast growth factor receptor 2 (FGFR2)-mediated reciprocal regulation loop between FGF8 and FGF10 is essential for limb induction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

9 May 2019

FGF10/FGFR2b signaling plays essential roles during in vivo embryonic submandibular salivary gland morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

9 May 2019

Endocardial and epicardial derived FGF signals regulate myocardial proliferation and differentiation in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

9 May 2019

betaKlotho is required for fibroblast growth factor (FGF) 21 signaling through FGF receptor (FGFR) 1c and FGFR3c

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

9 May 2019

The mouse seminal vesicle shape mutation is allelic with Fgfr2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

9 May 2019

Fibroblast growth factor signals regulate a wave of Hedgehog activation that is essential for coronary vascular development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

9 May 2019

regulation of smoothened signaling pathway

1 reference

9 May 2019

Stomach development is dependent on fibroblast growth factor 10/fibroblast growth factor receptor 2b-mediated signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

positive regulation of gene expression

1 reference

9 May 2019

Retinaldehyde dehydrogenase 2 is down-regulated during duodenal atresia formation in Fgfr2IIIb-/- mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

regulation of cell population proliferation

1 reference

9 May 2019

Conditional inactivation of FGF receptor 2 reveals an essential role for FGF signaling in the regulation of osteoblast function and bone growth

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

inner ear morphogenesis

1 reference

9 May 2019

FGF/FGFR-2(IIIb) signaling is essential for inner ear morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

positive regulation of cell population proliferation

7 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P21803&geneProductId=UniProtKB:P21803

24 April 2018

Fgfr2 is required for the development of the medial prefrontal cortex and its connections with limbic circuits

http://www.ebi.ac.uk/QuickGO/annotations?protein=P21803&geneProductId=UniProtKB:P21803

24 April 2018

A crucial role for Fgfr2-IIIb signalling in epidermal development and hair follicle patterning

http://www.ebi.ac.uk/QuickGO/annotations?protein=P21803&geneProductId=UniProtKB:P21803

24 April 2018

Disruption of Fgf10/Fgfr2b-coordinated epithelial-mesenchymal interactions causes cleft palate

http://www.ebi.ac.uk/QuickGO/annotations?protein=P21803&geneProductId=UniProtKB:P21803

24 April 2018

betaKlotho is required for fibroblast growth factor (FGF) 21 signaling through FGF receptor (FGFR) 1c and FGFR3c

http://www.ebi.ac.uk/QuickGO/annotations?protein=P21803&geneProductId=UniProtKB:P21803

24 April 2018

Fibroblast growth factor signals regulate a wave of Hedgehog activation that is essential for coronary vascular development

http://www.ebi.ac.uk/QuickGO/annotations?protein=P21803&geneProductId=UniProtKB:P21803

http://www.ebi.ac.uk/QuickGO/annotations?protein=P21803&geneProductId=UniProtKB:P21803

24 April 2018

synaptic vesicle transport

1 reference

9 May 2019

Distinct target-derived signals organize formation, maturation, and maintenance of motor nerve terminals

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

peptidyl-tyrosine phosphorylation

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

digestive tract development

1 reference

9 May 2019

A genetic mechanism for cecal atresia: the role of the Fgf10 signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

regulation of epithelial cell proliferation

2 references

9 May 2019

Fibroblast growth factor receptor 2 tyrosine kinase is required for prostatic morphogenesis and the acquisition of strict androgen dependency for adult tissue homeostasis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

9 May 2019

Role of epithelial cell fibroblast growth factor receptor substrate 2alpha in prostate development, regeneration and tumorigenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

bone development

1 reference

9 May 2019

Levels of mesenchymal FGFR2 signaling modulate smooth muscle progenitor cell commitment in the lung

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

epithelial tube branching involved in lung morphogenesis

1 reference

9 May 2019

Lung epithelial branching program antagonizes alveolar differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

positive regulation of cell division

1 reference

9 May 2019

A crucial role for Fgfr2-IIIb signalling in epidermal development and hair follicle patterning

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

positive regulation of transcription by RNA polymerase II

otic vesicle formation

embryonic cranial skeleton morphogenesis

TAS

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

epithelial to mesenchymal transition

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

positive regulation of smooth muscle cell proliferation

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

negative regulation of epithelial cell proliferation

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

positive regulation of cell population proliferation

8 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

9 May 2019

Fgfr2 is required for the development of the medial prefrontal cortex and its connections with limbic circuits

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

9 May 2019

A crucial role for Fgfr2-IIIb signalling in epidermal development and hair follicle patterning

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

9 May 2019

Disruption of Fgf10/Fgfr2b-coordinated epithelial-mesenchymal interactions causes cleft palate

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

9 May 2019

betaKlotho is required for fibroblast growth factor (FGF) 21 signaling through FGF receptor (FGFR) 1c and FGFR3c

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

9 May 2019

Fibroblast growth factor signals regulate a wave of Hedgehog activation that is essential for coronary vascular development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

9 May 2019

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

negative regulation of signal transduction

1 reference

7 November 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P21803&geneProductId=UniProtKB:P21803

cell differentiation

1 reference

7 November 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P21803&geneProductId=UniProtKB:P21803

negative regulation of apoptotic process

1 reference

7 November 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P21803&geneProductId=UniProtKB:P21803

positive regulation of ERK1 and ERK2 cascade

transmembrane receptor protein tyrosine kinase signaling pathway

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21803

cell fate commitment

positive regulation of epithelial cell proliferation

has part(s)

immunoglobulin subtype

1 reference

immunoglobulin subtype 2

1 reference

tyrosine-protein kinase, catalytic domain

1 reference

tyrosine-protein kinase, active site

1 reference

serine-threonine/tyrosine-protein kinase, catalytic domain

1 reference

immunoglobulin-like domain

1 reference

protein kinase, ATP binding site

1 reference

immunoglobulin I-set

1 reference

protein kinase domain

1 reference