(Q14912604)

English

Notch 3

mammalian protein found in Mus musculus

uniprot:Q61982
Notch3
Notch gene homolog 3
neurogenic locus notch homolog protein 3

In more languages

Statements

1 reference

25 May 2022

UniProt protein ID

Neurogenic locus Notch 3

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q61982

Notch-like domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q61982

Growth factor receptor cysteine-rich domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q61982

Ankyrin repeat-containing domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q61982

membrane proteins

1 reference

based on heuristic

inferred from GOA cell component → membrane

Notch, NODP domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

based on heuristic

inferred from protein domain or family

Notch, NOD domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Domain of unknown function DUF3454, notch, protein family

1 reference

based on heuristic

inferred from protein domain or family

Ankyrin repeat-containing domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

EGF-like calcium-binding domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

EGF-like domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

EGF-like, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

EGF-like calcium-binding, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

Ankyrin repeat, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

calcium ion binding

determination method

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61982

determination method

protein binding

determination method

4 references

9 May 2019

Mouse jagged1 physically interacts with notch2 and other notch receptors. Assessment by quantitative methods

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61982

determination method

9 May 2019

RBP-L, a transcription factor related to RBP-Jkappa

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61982

determination method

9 May 2019

A protein (ORF2) encoded by the latency-related gene of bovine herpesvirus 1 interacts with Notch1 and Notch3

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61982

determination method

9 May 2019

A protein (ORF2) encoded by the latency-related gene of bovine herpesvirus 1 interacts with Notch1 and Notch3

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61982

determination method

determination method

1 reference

9 May 2019

Asparaginyl hydroxylation of the Notch ankyrin repeat domain by factor inhibiting hypoxia-inducible factor

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61982

determination method

signaling receptor activity

determination method

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61982&geneProductId=UniProtKB:Q61982

determination method

cadherin binding

determination method

1 reference

5 June 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61982&geneProductId=UniProtKB:Q61982

determination method

signaling receptor activity

determination method

signaling receptor activity

determination method

4 references

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61982

determination method

9 May 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61982

determination method

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61982

determination method

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61982

determination method

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61982

determination method

integral component of plasma membrane

determination method

1 reference

9 May 2019

Mouse jagged1 physically interacts with notch2 and other notch receptors. Assessment by quantitative methods

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61982

determination method

plasma membrane

determination method

3 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61982&geneProductId=UniProtKB:Q61982

determination method

24 April 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61982&geneProductId=UniProtKB:Q61982

determination method

24 April 2018

Canonical notch signaling functions as a commitment switch in the epidermal lineage

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61982&geneProductId=UniProtKB:Q61982

determination method

plasma membrane

determination method

5 references

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61982&geneProductId=UniProtKB:Q61982

determination method

5 June 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61982&geneProductId=UniProtKB:Q61982

determination method

5 June 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61982&geneProductId=UniProtKB:Q61982

determination method

5 June 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61982&geneProductId=UniProtKB:Q61982

determination method

5 June 2018

Canonical notch signaling functions as a commitment switch in the epidermal lineage

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61982&geneProductId=UniProtKB:Q61982

determination method

plasma membrane

determination method

6 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61982

determination method

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61982

determination method

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61982

determination method

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61982

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61982

determination method

14 February 2019

Canonical notch signaling functions as a commitment switch in the epidermal lineage

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61982

determination method

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61982

determination method

plasma membrane

determination method

7 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61982

determination method

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61982

determination method

9 May 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61982

determination method

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61982

determination method

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61982

determination method

9 May 2019

Canonical notch signaling functions as a commitment switch in the epidermal lineage

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61982

determination method

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61982

determination method

determination method

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61982

determination method

receptor complex

determination method

3 references

9 May 2019

Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61982

determination method

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61982

determination method

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61982

determination method

biological process

negative regulation of neuron differentiation

determination method

1 reference

9 May 2019

Functional diversity of notch family genes in fetal lung development

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61982

determination method

negative regulation of cell differentiation

determination method

1 reference

9 May 2019

Functional diversity of notch family genes in fetal lung development

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61982

determination method

glomerular capillary formation

determination method

1 reference

9 May 2019

Segmental expression of Notch and Hairy genes in nephrogenesis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61982

determination method

negative regulation of transcription by RNA polymerase II

determination method

1 reference

9 May 2019

Transcriptome analysis for Notch3 target genes identifies Grip2 as a novel regulator of myogenic response in the cerebrovasculature

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61982

determination method

transcription, DNA-templated

determination method

1 reference

21 June 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61982&geneProductId=UniProtKB:Q61982

determination method

artery morphogenesis

determination method

1 reference

9 May 2019

Transcriptome analysis for Notch3 target genes identifies Grip2 as a novel regulator of myogenic response in the cerebrovasculature

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61982

determination method

forebrain development

determination method

1 reference

9 May 2019

Notch signaling coordinates the patterning of striatal compartments

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61982

determination method

neuron fate commitment

determination method

1 reference

9 May 2019

Notch signaling coordinates the patterning of striatal compartments

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61982

determination method

positive regulation of transcription by RNA polymerase II

determination method

1 reference

9 May 2019

Transcriptome analysis for Notch3 target genes identifies Grip2 as a novel regulator of myogenic response in the cerebrovasculature

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61982

determination method

positive regulation of smooth muscle cell proliferation

determination method

1 reference

9 May 2019

Notch3 signaling promotes the development of pulmonary arterial hypertension

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61982

determination method

regulation of developmental process

determination method

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61982

determination method

Notch signaling pathway

determination method

5 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61982

determination method

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61982

determination method

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61982

determination method

14 February 2019

Notch3 signaling promotes the development of pulmonary arterial hypertension

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61982

determination method

14 February 2019

Mouse jagged1 physically interacts with notch2 and other notch receptors. Assessment by quantitative methods

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61982

determination method

Notch signaling pathway

determination method

6 references

9 May 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61982

determination method

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61982

determination method

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61982

determination method

9 May 2019

Notch3 signaling promotes the development of pulmonary arterial hypertension

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61982

determination method

9 May 2019

Mouse jagged1 physically interacts with notch2 and other notch receptors. Assessment by quantitative methods

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61982

determination method

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61982

determination method

ankyrin repeat-containing domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q61982

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q61982

EGF-like calcium-binding, conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q61982

EGF-like calcium-binding domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q61982

EGF-like, conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q61982

Notch, NOD domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q61982

EGF-type aspartate/asparagine hydroxylation site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q61982

Notch, NODP domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q61982

Domain of unknown function DUF3454, notch

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q61982

EGF-like domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q61982

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q61982

Identifiers

RefSeq protein ID

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

ENSMUSP00000085016

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000085016

ENSMUSP00000158243

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000158243

Sitelinks

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Wiktionary(0 entries)

Multilingual sites(0 entries)

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