Wikidata

(Q1500343)

English

Potassium voltage-gated channel subfamily E regulatory subunit 1

mammalian protein found in Homo sapiens

  • delayed rectifier potassium channel subunit IsK
  • IKs producing slow voltage-gated potassium channel subunit beta Mink
  • potassium voltage-gated channel, Isk-related family, member 1
  • minimal potassium channel
  • potassium voltage-gated channel, Isk-related subfamily, member 1
  • cardiac delayed rectifier potassium channel protein
  • potassium channel, voltage gated subfamily E regulatory beta subunit 1
  • potassium voltage-gated channel subfamily E member 1
  • voltage gated potassiun channel accessory subunit
  • KCNE1
In more languages

Statements

molecular function
delayed rectifier potassium channel activity
determination method
IDA
7 references
retrieved
26 September 2017
stated in
A KCNQ1 mutation contributes to the concealed type 1 long QT phenotype by limiting the Kv7.1 channel conformational changes associated with protein kinase A phosphorylation
GOA
curator
UniProt
UniProt protein ID
P15382
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P15382&geneProductId=UniProtKB:P15382
determination method
IDA
retrieved
26 September 2017
stated in
Coassembly of K(V)LQT1 and minK (IsK) proteins to form cardiac I(Ks) potassium channel
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P15382&geneProductId=UniProtKB:P15382
determination method
IDA
retrieved
26 September 2017
stated in
Mutations in the hminK gene cause long QT syndrome and suppress IKs function
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P15382&geneProductId=UniProtKB:P15382
determination method
IDA
retrieved
26 September 2017
stated in
Augmented potassium current is a shared phenotype for two genetic defects associated with familial atrial fibrillation
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P15382&geneProductId=UniProtKB:P15382
determination method
IDA
retrieved
26 September 2017
stated in
Cellular dysfunction of LQT5-minK mutants: abnormalities of IKs, IKr and trafficking in long QT syndrome
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P15382&geneProductId=UniProtKB:P15382
determination method
IDA
retrieved
26 September 2017
stated in
AKAP proteins anchor cAMP-dependent protein kinase to KvLQT1/IsK channel complex
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P15382&geneProductId=UniProtKB:P15382
determination method
IDA
retrieved
26 September 2017
stated in
KCNQ1 gain-of-function mutation in familial atrial fibrillation
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P15382&geneProductId=UniProtKB:P15382
determination method
IDA
protein binding
determination method
IPI
6 references
retrieved
8 April 2019
stated in
KCNE2 confers background current characteristics to the cardiac KCNQ1 potassium channel
GOA
curator
UniProt
UniProt protein ID
P15382
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15382
determination method
IPI
retrieved
8 April 2019
stated in
Analysis of the interactions between the C-terminal cytoplasmic domains of KCNQ1 and KCNE1 channel subunits
GOA
curator
UniProt
UniProt protein ID
P15382
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15382
determination method
IPI
retrieved
8 April 2019
stated in
Impact of KCNE subunits on KCNQ1 (Kv7.1) channel membrane surface targeting
GOA
curator
UniProt
UniProt protein ID
P15382
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15382
determination method
IPI
retrieved
8 April 2019
stated in
Long QT mutations at the interface between KCNQ1 helix C and KCNE1 disrupt I(KS) regulation by PKA and PIP₂
GOA
curator
UniProt
UniProt protein ID
P15382
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15382
determination method
IPI
retrieved
8 April 2019
stated in
Intracellular domains interactions and gated motions of I(KS) potassium channel subunits
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15382
determination method
IPI
retrieved
8 April 2019
stated in
Specific interaction of the potassium channel beta-subunit minK with the sarcomeric protein T-cap suggests a T-tubule-myofibril linking system
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15382
determination method
IPI
delayed rectifier potassium channel activity
determination method
IBA
IDA
8 references
retrieved
8 April 2019
stated in
A KCNQ1 mutation contributes to the concealed type 1 long QT phenotype by limiting the Kv7.1 channel conformational changes associated with protein kinase A phosphorylation
GOA
curator
UniProt
UniProt protein ID
P15382
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15382
determination method
IDA
retrieved
8 April 2019
stated in
Coassembly of K(V)LQT1 and minK (IsK) proteins to form cardiac I(Ks) potassium channel
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15382
determination method
IDA
retrieved
8 April 2019
stated in
Cellular dysfunction of LQT5-minK mutants: abnormalities of IKs, IKr and trafficking in long QT syndrome
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15382
determination method
IDA
retrieved
8 April 2019
stated in
KCNQ1 gain-of-function mutation in familial atrial fibrillation
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15382
determination method
IDA
retrieved
8 April 2019
stated in
Mutations in the hminK gene cause long QT syndrome and suppress IKs function
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15382
determination method
IDA
retrieved
8 April 2019
stated in
Augmented potassium current is a shared phenotype for two genetic defects associated with familial atrial fibrillation
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15382
determination method
IDA
retrieved
8 April 2019
stated in
AKAP proteins anchor cAMP-dependent protein kinase to KvLQT1/IsK channel complex
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15382
determination method
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15382
determination method
IBA
potassium channel regulator activity
determination method
IBA
IDA
6 references
retrieved
8 April 2019
stated in
Cloning and function of the rat colonic epithelial K+ channel KVLQT1
GOA
curator
UniProt
UniProt protein ID
P15382
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15382
determination method
IDA
retrieved
8 April 2019
stated in
Regulation of the Kv2.1 potassium channel by MinK and MiRP1
GOA
curator
UniProt
UniProt protein ID
P15382
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15382
determination method
IDA
retrieved
8 April 2019
stated in
Coassembly of K(V)LQT1 and minK (IsK) proteins to form cardiac I(Ks) potassium channel
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15382
determination method
IDA
retrieved
8 April 2019
stated in
Cellular dysfunction of LQT5-minK mutants: abnormalities of IKs, IKr and trafficking in long QT syndrome
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15382
determination method
IDA
retrieved
8 April 2019
stated in
KCNQ1 gain-of-function mutation in familial atrial fibrillation
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15382
determination method
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15382
determination method
IBA
cell component
biological process
Gene Atlas image
PBB GE KCNE1 208514 at fs.png
732 × 530; 11 KB
0 references

Identifiers

 
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