(Q15311709)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P60766

cdc42

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P60766

membrane protein

1 reference

based on heuristic

inferred from GOA cell component → membrane

Small GTP-binding protein domain family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

Rho GDP-dissociation inhibitor binding

1 reference

16 July 2018

Identification of a novel prenyl and palmitoyl modification at the CaaX motif of Cdc42 that regulates RhoGDI binding

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

GTP-dependent protein binding

1 reference

14 February 2019

The mammalian homologue of the Caenorhabditis elegans polarity protein PAR-6 is a binding partner for the Rho GTPases Cdc42 and Rac1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

protein binding

14 references

14 February 2019

The mammalian homologue of the Caenorhabditis elegans polarity protein PAR-6 is a binding partner for the Rho GTPases Cdc42 and Rac1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

14 February 2019

The Rho-specific GEF Lfc interacts with neurabin and spinophilin to regulate dendritic spine morphology

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

14 February 2019

Expression, synaptic localization, and developmental regulation of Ack1/Pyk1, a cytoplasmic tyrosine kinase highly expressed in the developing and adult brain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

14 February 2019

IQGAP3 regulates cell proliferation through the Ras/ERK signalling cascade

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

14 February 2019

Ccpg1, a novel scaffold protein that regulates the activity of the Rho guanine nucleotide exchange factor Dbs

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

14 February 2019

A new family of Cdc42 effector proteins, CEPs, function in fibroblast and epithelial cell shape changes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

14 February 2019

FGD2, a CDC42-specific exchange factor expressed by antigen-presenting cells, localizes to early endosomes and active membrane ruffles

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

14 February 2019

TCGAP, a multidomain Rho GTPase-activating protein involved in insulin-stimulated glucose transport

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

14 February 2019

The adenomatous polyposis coli-associated exchange factors Asef and Asef2 are required for adenoma formation in Apc(Min/+)mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

14 February 2019

Bves directly interacts with GEFT, and controls cell shape and movement through regulation of Rac1/Cdc42 activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

14 February 2019

A direct interaction between Cdc42 and vesicle-associated membrane protein 2 regulates SNARE-dependent insulin exocytosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

14 February 2019

Affixin activates Rac1 via betaPIX in C2C12 myoblast

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

14 February 2019

ACF7 regulates cytoskeletal-focal adhesion dynamics and migration and has ATPase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

14 February 2019

Plexin-B1 directly interacts with PDZ-RhoGEF/LARG to regulate RhoA and growth cone morphology

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

nucleotide binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

1 reference

14 February 2019

GTP binding

CBAP functions as a novel component in chemokine-induced ZAP70-mediated T-cell adhesion and migration

5 references

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

21 June 2018

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

21 June 2018

Cdc42 controls progenitor cell differentiation and beta-catenin turnover in skin

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

GTPase activity

The Borgs, a new family of Cdc42 and TC10 GTPase-interacting proteins

8 references

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

16 July 2018

Multifunctional roles for the PH domain of Dbs in regulating Rho GTPase activation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

ISA

16 July 2018

FGD2, a CDC42-specific exchange factor expressed by antigen-presenting cells, localizes to early endosomes and active membrane ruffles

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

16 July 2018

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

16 July 2018

FGD2, a CDC42-specific exchange factor expressed by antigen-presenting cells, localizes to early endosomes and active membrane ruffles

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

16 July 2018

Vav GEFs are required for beta2 integrin-dependent functions of neutrophils

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

16 July 2018

Functional analysis of ARHGAP6, a novel GTPase-activating protein for RhoA

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

protein kinase binding

1 reference

5 June 2018

ARHGEF7 (Beta-PIX) acts as guanine nucleotide exchange factor for leucine-rich repeat kinase 2

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

thioesterase binding

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

GBD domain binding

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

apolipoprotein A-I receptor binding

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

identical protein binding

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

ubiquitin protein ligase activity

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

GTP binding

CBAP functions as a novel component in chemokine-induced ZAP70-mediated T-cell adhesion and migration

4 references

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

16 July 2018

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

GTPase activity

The Borgs, a new family of Cdc42 and TC10 GTPase-interacting proteins

8 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

14 February 2019

Multifunctional roles for the PH domain of Dbs in regulating Rho GTPase activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

ISA

14 February 2019

FGD2, a CDC42-specific exchange factor expressed by antigen-presenting cells, localizes to early endosomes and active membrane ruffles

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

14 February 2019

14 February 2019

Functional analysis of ARHGAP6, a novel GTPase-activating protein for RhoA

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

14 February 2019

Vav GEFs are required for beta2 integrin-dependent functions of neutrophils

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

14 February 2019

FGD2, a CDC42-specific exchange factor expressed by antigen-presenting cells, localizes to early endosomes and active membrane ruffles

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

GTP binding

CBAP functions as a novel component in chemokine-induced ZAP70-mediated T-cell adhesion and migration

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

mitogen-activated protein kinase kinase kinase binding

1 reference

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

cell component

cytoplasm

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

5 references

16 July 2018

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

16 July 2018

Uncovering early response of gene regulatory networks in ESCs by systematic induction of transcription factors

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

16 July 2018

Identification of a novel prenyl and palmitoyl modification at the CaaX motif of Cdc42 that regulates RhoGDI binding

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

16 July 2018

E-cadherin is essential for in vivo epidermal barrier function by regulating tight junctions

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

cytosol

1 reference

14 February 2019

Cool-1/βPIX functions as a guanine nucleotide exchange factor in the cycling of Cdc42 to regulate insulin secretion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

cell-cell junction

1 reference

14 February 2019

The lymphoid lineage-specific actin-uncapping protein Rltpr is essential for costimulation via CD28 and the development of regulatory T cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

microtubule organizing center

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

1 reference

14 February 2019

storage vacuole

1 reference

14 February 2019

Cool-1/βPIX functions as a guanine nucleotide exchange factor in the cycling of Cdc42 to regulate insulin secretion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

cytoskeleton

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

1 reference

14 February 2019

myelin sheath

1 reference

7 November 2018

Proteolipid protein is required for transport of sirtuin 2 into CNS myelin

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

apical part of cell

1 reference

14 February 2019

The Rho-GTPase cdc42 regulates neural progenitor fate at the apical surface

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

leading edge membrane

1 reference

14 February 2019

DOCK8 is a Cdc42 activator critical for interstitial dendritic cell migration during immune responses

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

cell periphery

1 reference

14 February 2019

Uncovering early response of gene regulatory networks in ESCs by systematic induction of transcription factors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

intracellular anatomical structure

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

1 reference

10 September 2018

spindle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

1 reference

14 February 2019

lamellipodium membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

1 reference

14 February 2019

cell projection

phagocytic vesicle

1 reference

14 February 2019

The phagosomal proteome in interferon-gamma-activated macrophages

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

spindle midzone

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

1 reference

14 February 2019

mitotic spindle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

1 reference

14 February 2019

plasma membrane

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

7 references

16 July 2018

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

16 July 2018

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

16 July 2018

Cool-1/βPIX functions as a guanine nucleotide exchange factor in the cycling of Cdc42 to regulate insulin secretion

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

16 July 2018

Identification of a novel prenyl and palmitoyl modification at the CaaX motif of Cdc42 that regulates RhoGDI binding

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

16 July 2018

Phosphoinositide 3-kinase p85beta regulates invadopodium formation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

centrosome

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

Golgi transport complex

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

filopodium

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

protein-containing complex

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

cytoplasmic ribonucleoprotein granule

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

neuron projection

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

soma

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

dendritic spine

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

Schaffer collateral - CA1 synapse

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

Golgi membrane

1 reference

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

cytoplasm

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

4 references

14 February 2019

14 February 2019

E-cadherin is essential for in vivo epidermal barrier function by regulating tight junctions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

14 February 2019

Uncovering early response of gene regulatory networks in ESCs by systematic induction of transcription factors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

plasma membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

7 references

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

14 February 2019

Cool-1/βPIX functions as a guanine nucleotide exchange factor in the cycling of Cdc42 to regulate insulin secretion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

14 February 2019

Phosphoinositide 3-kinase p85beta regulates invadopodium formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

cell cortex

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

secretory granule

1 reference

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

cell projection

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

3 references

14 February 2019

14 February 2019

Local phosphatidylinositol 3,4,5-trisphosphate accumulation recruits Vav2 and Vav3 to activate Rac1/Cdc42 and initiate neurite outgrowth in nerve growth factor-stimulated PC12 cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

neuron projection

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

dendritic spine

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

Schaffer collateral - CA1 synapse

1 reference

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

myelin sheath

HDA

1 reference

14 February 2019

Proteolipid protein is required for transport of sirtuin 2 into CNS myelin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

cardiac conduction system development

HDA

biological process

1 reference

14 February 2019

Tinman/Nkx2-5 acts via miR-1 and upstream of Cdc42 to regulate heart function across species

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

positive regulation of protein phosphorylation

1 reference

21 June 2018

Cdc42 controls progenitor cell differentiation and beta-catenin turnover in skin

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

keratinization

1 reference

21 June 2018

Cdc42 controls progenitor cell differentiation and beta-catenin turnover in skin

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

actin filament bundle assembly

1 reference

21 June 2018

Cdc42 controls progenitor cell differentiation and beta-catenin turnover in skin

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

endosomal transport

1 reference

14 February 2019

The mammalian homologue of the Caenorhabditis elegans polarity protein PAR-6 is a binding partner for the Rho GTPases Cdc42 and Rac1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

hair follicle morphogenesis

1 reference

21 June 2018

Cdc42 controls progenitor cell differentiation and beta-catenin turnover in skin

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

heart contraction

1 reference

14 February 2019

Tinman/Nkx2-5 acts via miR-1 and upstream of Cdc42 to regulate heart function across species

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

regulation of protein stability

1 reference

21 June 2018

Cdc42 controls progenitor cell differentiation and beta-catenin turnover in skin

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

neuron fate determination

1 reference

14 February 2019

The Rho-GTPase cdc42 regulates neural progenitor fate at the apical surface

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

epithelial-mesenchymal cell signaling

1 reference

21 June 2018

Cdc42 controls progenitor cell differentiation and beta-catenin turnover in skin

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

negative regulation of gene expression

1 reference

21 June 2018

Cdc42 controls progenitor cell differentiation and beta-catenin turnover in skin

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

positive regulation of peptidyl-serine phosphorylation

1 reference

21 June 2018

Cdc42 controls progenitor cell differentiation and beta-catenin turnover in skin

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

establishment or maintenance of cell polarity

1 reference

16 July 2018

The mammalian homologue of the Caenorhabditis elegans polarity protein PAR-6 is a binding partner for the Rho GTPases Cdc42 and Rac1

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

regulation of protein metabolic process

1 reference

21 June 2018

Cdc42 controls progenitor cell differentiation and beta-catenin turnover in skin

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

establishment or maintenance of apical/basal cell polarity

1 reference

14 February 2019

The Rho-GTPase cdc42 regulates neural progenitor fate at the apical surface

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

regulation of protein kinase activity

1 reference

21 June 2018

Cdc42 controls progenitor cell differentiation and beta-catenin turnover in skin

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

positive regulation of hair follicle cell proliferation

1 reference

21 June 2018

Cdc42 controls progenitor cell differentiation and beta-catenin turnover in skin

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

positive regulation of MAPK cascade

1 reference

14 February 2019

Cdo promotes neuronal differentiation via activation of the p38 mitogen-activated protein kinase pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

regulation of mitotic nuclear division

1 reference

14 February 2019

The Rho-GTPase cdc42 regulates neural progenitor fate at the apical surface

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

hair follicle placode formation

1 reference

21 June 2018

Cdc42 controls progenitor cell differentiation and beta-catenin turnover in skin

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

cell differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

1 reference

14 February 2019

positive regulation of epithelial cell proliferation involved in lung morphogenesis

1 reference

14 February 2019

CDC42 is required for structural patterning of the lung during development

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

regulation of protein heterodimerization activity

1 reference

14 February 2019

Cdo promotes neuronal differentiation via activation of the p38 mitogen-activated protein kinase pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

multicellular organism growth

1 reference

21 June 2018

Cdc42 controls progenitor cell differentiation and beta-catenin turnover in skin

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

small GTPase mediated signal transduction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

1 reference

14 February 2019

epidermis morphogenesis

1 reference

21 June 2018

Cdc42 controls progenitor cell differentiation and beta-catenin turnover in skin

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

nucleus localization

1 reference

14 February 2019

The Rho-GTPase cdc42 regulates neural progenitor fate at the apical surface

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

epithelial cell-cell adhesion

1 reference

21 June 2018

Cdc42 controls progenitor cell differentiation and beta-catenin turnover in skin

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

nervous system development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

1 reference

14 February 2019

dendritic cell migration

1 reference

14 February 2019

DOCK8 is a Cdc42 activator critical for interstitial dendritic cell migration during immune responses

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

keratinocyte development

1 reference

21 June 2018

Cdc42 controls progenitor cell differentiation and beta-catenin turnover in skin

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

regulation of protein catabolic process

1 reference

21 June 2018

Cdc42 controls progenitor cell differentiation and beta-catenin turnover in skin

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

canonical Wnt signaling pathway

1 reference

21 June 2018

Cdc42 controls progenitor cell differentiation and beta-catenin turnover in skin

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

adherens junction organization

1 reference

14 February 2019

The Rho-GTPase cdc42 regulates neural progenitor fate at the apical surface

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

endocytosis

1 reference

16 July 2018

CLN3 deficient cells display defects in the ARF1-Cdc42 pathway and actin-dependent events

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

filopodium assembly

1 reference

14 February 2019

Functional analysis of ARHGAP6, a novel GTPase-activating protein for RhoA

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

positive regulation of phosphatidylinositol 3-kinase activity

1 reference

14 February 2019

Local phosphatidylinositol 3,4,5-trisphosphate accumulation recruits Vav2 and Vav3 to activate Rac1/Cdc42 and initiate neurite outgrowth in nerve growth factor-stimulated PC12 cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

positive regulation of gene expression

1 reference

21 June 2018

Cdc42 controls progenitor cell differentiation and beta-catenin turnover in skin

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

Rho protein signal transduction

1 reference

16 July 2018

The Borgs, a new family of Cdc42 and TC10 GTPase-interacting proteins

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

submandibular salivary gland formation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

dendritic spine morphogenesis

1 reference

14 February 2019

The RhoGEF DOCK10 is essential for dendritic spine morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

cell-cell adhesion

cellular response to interferon-gamma

1 reference

14 February 2019

The phagosomal proteome in interferon-gamma-activated macrophages

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

phagocytosis, engulfment

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

1 reference

14 February 2019

positive regulation of cytokinesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

1 reference

14 February 2019

cell junction assembly

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

1 reference

14 February 2019

establishment of epithelial cell apical/basal polarity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

1 reference

14 February 2019

regulation of filopodium assembly

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

1 reference

14 February 2019

positive regulation of filopodium assembly

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

1 reference

14 February 2019

regulation of attachment of spindle microtubules to kinetochore

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

1 reference

14 February 2019

positive regulation of substrate adhesion-dependent cell spreading

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

1 reference

14 February 2019

actin filament organization

integrin-mediated signaling pathway

3 references

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

regulation of lamellipodium assembly

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

positive regulation of lamellipodium assembly

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

protein ubiquitination

1 reference

16 July 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

actin cytoskeleton organization

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

positive regulation of cell growth

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

positive regulation of pseudopodium assembly

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

negative regulation of protein-containing complex assembly

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

neuropilin signaling pathway

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

viral RNA genome replication

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

regulation of stress fiber assembly

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

positive regulation of stress fiber assembly

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

positive regulation of actin cytoskeleton reorganization

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

cell-cell adhesion

1 reference

14 February 2019

The mammalian homologue of the Caenorhabditis elegans polarity protein PAR-6 is a binding partner for the Rho GTPases Cdc42 and Rac1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

regulation of modification of postsynaptic structure

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

sprouting angiogenesis

1 reference

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

actin filament organization

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

3 references

7 November 2018

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

7 November 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

Golgi organization

1 reference

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

establishment or maintenance of cell polarity

regulation of cell shape

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

cell projection assembly

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

actin cytoskeleton organization

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

positive regulation of catalytic activity

1 reference

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

positive regulation of neuron apoptotic process

1 reference

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

positive regulation of DNA replication

1 reference

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

positive regulation of JNK cascade

1 reference

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

establishment of Golgi localization

1 reference

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

positive regulation of synapse structural plasticity

1 reference

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

organelle transport along microtubule

1 reference

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

actin filament branching

1 reference

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

positive regulation of intracellular protein transport

1 reference

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

regulation of modification of postsynaptic structure

1 reference

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60766&geneProductId=UniProtKB:P60766

actin filament organization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

4 references

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

Cdc42 protein signal transduction

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

regulation of actin cytoskeleton organization

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

modification of synaptic structure

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60766

small GTP-binding protein domain

has part(s)

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P60766

Identifiers

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

25 May 2022

1 reference

1 reference

1 reference

10 August 2016

1 reference

10 August 2016

1 reference

10 August 2016

1 reference

10 August 2016

1 reference

10 August 2016