(Q15332289)

English

Toll-like receptor 6

mammalian protein found in Mus musculus

toll-like receptor 6
Tlr6
uniprot:Q9EPW9

In more languages

Statements

1 reference

25 May 2022

UniProt protein ID

Toll/interleukin-1 receptor homology (TIR) domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9EPW9

Leucine-rich repeat domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9EPW9

Toll-like receptor 6

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9EPW9

membrane proteins

1 reference

based on heuristic

inferred from GOA cell component → membrane

Toll/interleukin-1 receptor homology (TIR) domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Cysteine-rich flanking region, C-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Leucine-rich repeat, typical subtype, protein family

1 reference

based on heuristic

inferred from protein domain or family

Leucine-rich repeat, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

diacyl lipopeptide binding

determination method

1 reference

14 February 2019

Recognition of lipopeptide patterns by Toll-like receptor 2-Toll-like receptor 6 heterodimer

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPW9

determination method

protein heterodimerization activity

determination method

1 reference

9 May 2017

Recognition of lipopeptide patterns by Toll-like receptor 2-Toll-like receptor 6 heterodimer

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q9EPW9

determination method

lipopeptide binding

determination method

1 reference

9 May 2017

Discrimination of bacterial lipoproteins by Toll-like receptor 6

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q9EPW9

determination method

transmembrane signaling receptor activity

determination method

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPW9

determination method

signaling receptor binding

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPW9

determination method

identical protein binding

determination method

2 references

lipopeptide binding

determination method

3 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPW9

determination method

14 February 2019

Discrimination of bacterial lipoproteins by Toll-like receptor 6

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPW9

determination method

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPW9

determination method

integral component of membrane

determination method

2 references

phagocytic vesicle membrane

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPW9

determination method

Golgi apparatus

determination method

3 references

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPW9

determination method

Toll-like receptor 2-Toll-like receptor 6 protein complex

determination method

1 reference

16 September 2017

Recognition of lipopeptide patterns by Toll-like receptor 2-Toll-like receptor 6 heterodimer

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9EPW9&geneProductId=UniProtKB:Q9EPW9

determination method

plasma membrane

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPW9

determination method

determination method

3 references

cytoplasmic vesicle

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPW9

determination method

integral component of plasma membrane

determination method

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPW9

determination method

intracellular anatomical structure

determination method

1 reference

16 September 2017

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9EPW9&geneProductId=UniProtKB:Q9EPW9

determination method

receptor complex

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPW9

determination method

biological process

positive regulation of NLRP3 inflammasome complex assembly

determination method

1 reference

14 February 2019

CD36 coordinates NLRP3 inflammasome activation by facilitating intracellular nucleation of soluble ligands into particulate ligands in sterile inflammation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPW9

determination method

immune system process

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPW9

determination method

positive regulation of JUN kinase activity

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPW9

determination method

toll-like receptor 6 signaling pathway

determination method

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPW9

determination method

MyD88-dependent toll-like receptor signaling pathway

determination method

1 reference

9 May 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q9EPW9

determination method

positive regulation of I-kappaB kinase/NF-kappaB signaling

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPW9

determination method

innate immune response

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPW9

determination method

signal transduction

determination method

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPW9

determination method

defense response to bacterium

determination method

1 reference

9 May 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q9EPW9

determination method

inflammatory response

determination method

2 references

cellular response to diacyl bacterial lipopeptide

determination method

3 references

cell activation

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPW9

determination method

toll-like receptor signaling pathway

determination method

1 reference

9 May 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q9EPW9

determination method

microglial cell activation

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPW9

determination method

inflammatory response

determination method

4 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPW9

determination method

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPW9

determination method

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPW9

determination method

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPW9

determination method

response to bacterial lipoprotein

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPW9

determination method

negative regulation of toll-like receptor 2 signaling pathway

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPW9

determination method

TRIF-dependent toll-like receptor signaling pathway

determination method

1 reference

14 February 2019

CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPW9

determination method

positive regulation of macrophage activation

determination method

1 reference

14 February 2019

CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPW9

determination method

positive regulation of nitric oxide biosynthetic process

determination method

1 reference

14 February 2019

CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPW9

determination method

nitric oxide metabolic process

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPW9

determination method

positive regulation of inflammatory response

determination method

1 reference

14 February 2019

CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPW9

determination method

positive regulation of NF-kappaB transcription factor activity

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPW9

determination method

cellular response to oxidised low-density lipoprotein particle stimulus

determination method

1 reference

14 February 2019

CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPW9

determination method

positive regulation of cytokine production involved in inflammatory response

determination method

1 reference

14 February 2019

CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPW9

determination method

positive regulation of oxidative stress-induced neuron death

determination method

1 reference

14 February 2019

CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPW9

determination method

positive regulation of reactive oxygen species biosynthetic process

determination method

1 reference

14 February 2019

CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPW9

determination method

cellular response to amyloid-beta

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPW9

determination method

Identifiers

RefSeq protein ID

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

ENSMUSP00000062096

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000062096

ENSMUSP00000143865

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000143865

ENSMUSP00000159286

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000159286

PDB structure ID

1 reference

UniProt protein ID

10 August 2016

language of work or name

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