(Q2006984)

Insulin-like growth factor II

1 reference

Insulin-like growth factor II E-peptide, C-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Insulin-like domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Insulin, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

insulin receptor binding

1 reference

8 April 2019

Insulin/insulin-like growth factor I hybrid receptors have different biological characteristics depending on the insulin receptor isoform involved

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01344

3 references

8 April 2019

Insulin-like growth factor binding protein 2 is a growth inhibitory protein conserved in zebrafish

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01344

8 April 2019

Structure and functional analysis of the IGF-II/IGF2R interaction

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01344

8 April 2019

A proteome-scale map of the human interactome network

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01344

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01344

IPI

growth factor activity

3 references

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01344

8 April 2019

Regulation of the Akt/Glycogen synthase kinase-3 axis by insulin-like growth factor-II via activation of the human insulin receptor isoform-A

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01344

insulin-like growth factor receptor binding

3 references

8 April 2019

Mutants of human insulin-like growth factor II with altered affinities for the type 1 and type 2 insulin-like growth factor receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01344

8 April 2019

Both type I and II insulin-like growth factor receptor binding increase during lactogenesis in bovine mammary tissue

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01344

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01344

1 reference

8 April 2019

Direct integrin binding to insulin-like growth factor-2 through the C-domain is required for insulin-like growth factor receptor type 1 (IGF1R) signaling.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01344

platelet alpha granule lumen

cell component

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01344

regulation of gene expression by genetic imprinting

biological process

1 reference

8 April 2019

Imprinting mutation in the Beckwith-Wiedemann syndrome leads to biallelic IGF2 expression through an H19-independent pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01344

skeletal system development

1 reference

8 April 2019

Constitutional relaxation of insulin-like growth factor II gene imprinting associated with Wilms' tumour and gigantism

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01344

insulin receptor signaling pathway

1 reference

8 April 2019

Mutants of human insulin-like growth factor II with altered affinities for the type 1 and type 2 insulin-like growth factor receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01344

positive regulation of protein kinase B signaling

1 reference

8 April 2019

Regulation of the Akt/Glycogen synthase kinase-3 axis by insulin-like growth factor-II via activation of the human insulin receptor isoform-A

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01344

regulation of transcription, DNA-templated

1 reference

8 April 2019

Differential gene expression induced by insulin and insulin-like growth factor-II through the insulin receptor isoform A

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01344

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01344

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01344

platelet degranulation

1 reference

8 April 2019

multicellular organism development

1 reference

8 April 2019

Insulin-like growth factor II precursor gene organization in relation to insulin gene family

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01344

glucose metabolic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01344

positive regulation of mitotic nuclear division

1 reference

8 April 2019

Regulation of the Akt/Glycogen synthase kinase-3 axis by insulin-like growth factor-II via activation of the human insulin receptor isoform-A

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01344

positive regulation of cell division

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01344

positive regulation of MAPK cascade

1 reference

8 April 2019

Regulation of the Akt/Glycogen synthase kinase-3 axis by insulin-like growth factor-II via activation of the human insulin receptor isoform-A

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01344

positive regulation of activated T cell proliferation

1 reference

8 April 2019

Effects of insulin-like growth factors and insulin-like growth factor binding protein-2 on the in vitro proliferation of peripheral blood mononuclear cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01344

positive regulation of protein serine/threonine kinase activity

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01344

carbohydrate metabolic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01344

regulation of signaling receptor activity

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01344

osteoblast differentiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01344

positive regulation of cell population proliferation

IC

animal organ morphogenesis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01344

exocrine pancreas development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01344

positive regulation of multicellular organism growth

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01344

positive regulation of transcription by RNA polymerase II

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01344

striated muscle cell differentiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01344

Gene Atlas image

PBB GE IGF2 202409 at fs.png
732 × 530; 10 KB

0 references

has part(s)

Insulin, conserved site

1 reference

Insulin-like growth factor II E-peptide, C-terminal

1 reference

Insulin-like

1 reference

Identifiers

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

28 October 2013

1 reference

5 August 2016

1 reference

5 August 2016

1 reference

5 August 2016

1 reference

5 August 2016

1 reference

5 August 2016