Wikidata

(Q21096296)

English

Peroxisomal biogenesis factor 5

mammalian protein found in Homo sapiens

  • PTS1-BP
  • peroxisomal targeting signal 1 receptor
  • peroxisomal targeting signal import receptor
  • peroxin-5
  • peroxisomal C-terminal targeting signal import receptor
  • peroxisomal import receptor 5
  • peroxisomal biogenesis factor 5
  • peroxisome receptor 1
  • PEX5
  • peroxisomal targeting signal 1 (SKL type) receptor
  • PTS1 receptor
  • peroxisomal targeting signal receptor 1
In more languages

Statements

molecular function
protein binding
determination method
IPI
14 references
retrieved
8 April 2019
stated in
Solution structure of human Pex5.Pex14.PTS1 protein complexes obtained by small angle X-ray scattering
GOA
curator
UniProt
UniProt protein ID
P50542
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50542
determination method
IPI
retrieved
8 April 2019
stated in
Molecular anatomy of the peroxin Pex12p: ring finger domain is essential for Pex12p function and interacts with the peroxisome-targeting signal type 1-receptor Pex5p and a ring peroxin, Pex10p
GOA
curator
UniProt
UniProt protein ID
P50542
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50542
determination method
IPI
retrieved
8 April 2019
stated in
PEX5 protein binds monomeric catalase blocking its tetramerization and releases it upon binding the N-terminal domain of PEX14
GOA
curator
UniProt
UniProt protein ID
P50542
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50542
determination method
IPI
retrieved
8 April 2019
stated in
Identification of a human PTS1 receptor docking protein directly required for peroxisomal protein import
GOA
curator
UniProt
UniProt protein ID
P50542
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50542
determination method
IPI
retrieved
8 April 2019
stated in
PEX14 is required for microtubule-based peroxisome motility in human cells
GOA
curator
UniProt
UniProt protein ID
P50542
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50542
determination method
IPI
retrieved
8 April 2019
stated in
C-terminal tripeptide Ser-Asn-Leu (SNL) of human D-aspartate oxidase is a functional peroxisome-targeting signal
GOA
curator
UniProt
UniProt protein ID
P50542
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50542
determination method
IPI
retrieved
8 April 2019
stated in
Characterization of human and murine PMP20 peroxisomal proteins that exhibit antioxidant activity in vitro
GOA
curator
UniProt
UniProt protein ID
P50542
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50542
determination method
IPI
retrieved
8 April 2019
stated in
Genome-wide YFP fluorescence complementation screen identifies new regulators for telomere signaling in human cells
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50542
determination method
IPI
retrieved
8 April 2019
stated in
PEX12 interacts with PEX5 and PEX10 and acts downstream of receptor docking in peroxisomal matrix protein import
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50542
determination method
IPI
retrieved
8 April 2019
stated in
Structural basis for competitive interactions of Pex14 with the import receptors Pex5 and Pex19
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50542
determination method
IPI
retrieved
8 April 2019
stated in
A proteome-scale map of the human interactome network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50542
determination method
IPI
retrieved
8 April 2019
stated in
PEX14 is required for microtubule-based peroxisome motility in human cells
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50542
determination method
IPI
retrieved
8 April 2019
stated in
Analysis of mammalian peroxin interactions using a non-transcription-based bacterial two-hybrid assay
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50542
determination method
IPI
retrieved
8 April 2019
stated in
Peroxisomal import of human alanine:glyoxylate aminotransferase requires ancillary targeting information remote from its C terminus
GOA
curator
HUGO Gene Nomenclature Committee
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50542
determination method
IPI
peroxisome matrix targeting signal-1 binding
determination method
IDA
IMP
IPI
7 references
retrieved
17 October 2017
stated in
A proteome-wide perspective on peroxisome targeting signal 1(PTS1)-Pex5p affinities
GOA
curator
UniProt
UniProt protein ID
P50542
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P50542&geneProductId=UniProtKB:P50542
determination method
IPI
retrieved
17 October 2017
stated in
The Peroxisomal Targeting Signal 1 in sterol carrier protein 2 is autonomous and essential for receptor recognition
GOA
curator
UniProt
UniProt protein ID
P50542
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P50542&geneProductId=UniProtKB:P50542
determination method
IPI
retrieved
17 October 2017
stated in
An isoform of pex5p, the human PTS1 receptor, is required for the import of PTS2 proteins into peroxisomes
GOA
curator
UniProt
UniProt protein ID
P50542
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P50542&geneProductId=UniProtKB:P50542
determination method
IMP
retrieved
17 October 2017
stated in
Mutations in the PTS1 receptor gene, PXR1, define complementation group 2 of the peroxisome biogenesis disorders
GOA
curator
UniProt
UniProt protein ID
P50542
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P50542&geneProductId=UniProtKB:P50542
determination method
IDA
retrieved
17 October 2017
stated in
Characterization of human and murine PMP20 peroxisomal proteins that exhibit antioxidant activity in vitro
GOA
curator
UniProt
UniProt protein ID
P50542
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P50542&geneProductId=UniProtKB:P50542
determination method
IDA
retrieved
17 October 2017
stated in
PEX5 binds the PTS1 independently of Hsp70 and the peroxin PEX12
GOA
curator
UniProt
UniProt protein ID
P50542
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P50542&geneProductId=UniProtKB:P50542
determination method
IDA
retrieved
17 October 2017
stated in
Identification of PEX5p-related novel peroxisome-targeting signal 1 (PTS1)-binding proteins in mammals
GOA
curator
UniProt
UniProt protein ID
P50542
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P50542&geneProductId=UniProtKB:P50542
determination method
IDA
peroxisome matrix targeting signal-1 binding
determination method
IBA
IDA
IPI
5 references
retrieved
8 April 2019
stated in
A proteome-wide perspective on peroxisome targeting signal 1(PTS1)-Pex5p affinities
GOA
curator
UniProt
UniProt protein ID
P50542
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50542
determination method
IPI
retrieved
8 April 2019
stated in
The Peroxisomal Targeting Signal 1 in sterol carrier protein 2 is autonomous and essential for receptor recognition
GOA
curator
UniProt
UniProt protein ID
P50542
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50542
determination method
IPI
retrieved
8 April 2019
stated in
Identification of PEX5p-related novel peroxisome-targeting signal 1 (PTS1)-binding proteins in mammals
GOA
curator
UniProt
UniProt protein ID
P50542
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50542
determination method
IDA
retrieved
8 April 2019
stated in
Characterization of human and murine PMP20 peroxisomal proteins that exhibit antioxidant activity in vitro
GOA
curator
UniProt
UniProt protein ID
P50542
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50542
determination method
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50542
determination method
IBA
cell component
biological process

Identifiers

RefSeq protein ID
Ensembl protein ID
 
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