(Q21097261)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q01484

Ankyrin repeat-containing domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q01484

auxiliary protein involved in transmembrane transport

1 reference

Transporter Classification Database ID

8.A.28.1.1

retrieved

2 October 2019

hierarchical database ID heuristic

Ankyrin repeat-containing domain, protein family

1 reference

Death domain, protein family

1 reference

ZU5 domain, protein family

1 reference

Ankyrin repeat, protein family

1 reference

protein-macromolecule adaptor activity

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

1 reference

8 April 2019

Ankyrin-B targets beta2-spectrin to an intracellular compartment in neonatal cardiomyocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

transmembrane transporter binding

IPI

3 references

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q01484&geneProductId=UniProtKB:Q01484

16 July 2018

Ankyrin-B regulates Kir6.2 membrane expression and function in heart

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q01484&geneProductId=UniProtKB:Q01484

16 July 2018

Defects in ankyrin-based membrane protein targeting pathways underlie atrial fibrillation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q01484&geneProductId=UniProtKB:Q01484

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

structural constituent of cytoskeleton

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

9 references

8 April 2019

The ammonium transporter RhBG: requirement of a tyrosine-based signal and ankyrin-G for basolateral targeting and membrane anchorage in polarized kidney epithelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

8 April 2019

Ankyrin-B targets beta2-spectrin to an intracellular compartment in neonatal cardiomyocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

8 April 2019

Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

8 April 2019

An ankyrin-based mechanism for functional organization of dystrophin and dystroglycan

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

8 April 2019

Dual role of K ATP channel C-terminal motif in membrane targeting and metabolic regulation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

8 April 2019

EH domain proteins regulate cardiac membrane protein targeting

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

8 April 2019

A Dynamic Protein Interaction Landscape of the Human Centrosome-Cilium Interface

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

8 April 2019

Defects in ankyrin-based membrane protein targeting pathways underlie atrial fibrillation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

8 April 2019

Targeting and stability of Na/Ca exchanger 1 in cardiomyocytes requires direct interaction with the membrane adaptor ankyrin-B

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

1 reference

8 April 2019

Asparagine and aspartate hydroxylation of the cytoskeletal ankyrin family is catalyzed by factor-inhibiting hypoxia-inducible factor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

Obscurin targets ankyrin-B and protein phosphatase 2A to the cardiac M-line

IPI

protein kinase binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

transmembrane transporter binding

IPI

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

8 April 2019

Defects in ankyrin-based membrane protein targeting pathways underlie atrial fibrillation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

8 April 2019

Ankyrin-B regulates Kir6.2 membrane expression and function in heart

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

phosphorylation-dependent protein binding

IBA

1 reference

8 April 2019

CK2-regulated schwannomin-interacting protein IQCJ-SCHIP-1 association with AnkG contributes to the maintenance of the axon initial segment

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

postsynaptic membrane

1 reference

8 April 2019

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q01484&geneProductId=UniProtKB:Q01484

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

1 reference

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q01484&geneProductId=UniProtKB:Q01484

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

intracellular anatomical structure

1 reference

16 July 2018

Targeting and stability of Na/Ca exchanger 1 in cardiomyocytes requires direct interaction with the membrane adaptor ankyrin-B

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q01484&geneProductId=UniProtKB:Q01484

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

basolateral plasma membrane

1 reference

8 April 2019

The ammonium transporter RhBG: requirement of a tyrosine-based signal and ankyrin-G for basolateral targeting and membrane anchorage in polarized kidney epithelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

1 reference

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q01484&geneProductId=UniProtKB:Q01484

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

apical plasma membrane

1 reference

8 April 2019

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

4 references

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q01484&geneProductId=UniProtKB:Q01484

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q01484&geneProductId=UniProtKB:Q01484

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q01484&geneProductId=UniProtKB:Q01484

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q01484&geneProductId=UniProtKB:Q01484

5 references

8 April 2019

Targeting and stability of Na/Ca exchanger 1 in cardiomyocytes requires direct interaction with the membrane adaptor ankyrin-B

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

positive regulation of potassium ion transmembrane transporter activity

IBA

biological process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

protein localization to organelle

1 reference

8 April 2019

A cardiac arrhythmia syndrome caused by loss of ankyrin-B function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

positive regulation of cation channel activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

regulation of cardiac muscle contraction by calcium ion signaling

1 reference

8 April 2019

Ankyrin-B mutation causes type 4 long-QT cardiac arrhythmia and sudden cardiac death

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

regulation of protein stability

1 reference

8 April 2019

Dysfunction in ankyrin-B-dependent ion channel and transporter targeting causes human sinus node disease

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion

IC

positive regulation of potassium ion transport

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

regulation of release of sequestered calcium ion into cytosol

1 reference

8 April 2019

Defining the cellular phenotype of "ankyrin-B syndrome" variants: human ANK2 variants associated with clinical phenotypes display a spectrum of activities in cardiomyocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

SA node cell action potential

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

Targeting and stability of Na/Ca exchanger 1 in cardiomyocytes requires direct interaction with the membrane adaptor ankyrin-B

protein stabilization

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

ventricular cardiac muscle cell action potential

1 reference

8 April 2019

Defining the cellular phenotype of "ankyrin-B syndrome" variants: human ANK2 variants associated with clinical phenotypes display a spectrum of activities in cardiomyocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

cellular calcium ion homeostasis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

positive regulation of calcium ion transmembrane transporter activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

nervous system development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

Dysfunction in ankyrin-B-dependent ion channel and transporter targeting causes human sinus node disease

regulation of heart rate

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

protein localization to M-band

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

endoplasmic reticulum to Golgi vesicle-mediated transport

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

regulation of cardiac muscle cell contraction

1 reference

8 April 2019

Defining the cellular phenotype of "ankyrin-B syndrome" variants: human ANK2 variants associated with clinical phenotypes display a spectrum of activities in cardiomyocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

protein localization to T-tubule

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

positive regulation of gene expression

1 reference

8 April 2019

Defining the cellular phenotype of "ankyrin-B syndrome" variants: human ANK2 variants associated with clinical phenotypes display a spectrum of activities in cardiomyocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

protein localization to cell surface

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

paranodal junction assembly

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

atrial cardiac muscle cell action potential

3 references

8 April 2019

Defining the cellular phenotype of "ankyrin-B syndrome" variants: human ANK2 variants associated with clinical phenotypes display a spectrum of activities in cardiomyocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

8 April 2019

Defects in ankyrin-based membrane protein targeting pathways underlie atrial fibrillation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

8 April 2019

Dysfunction in ankyrin-B-dependent ion channel and transporter targeting causes human sinus node disease

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

sarcoplasmic reticulum calcium ion transport

1 reference

8 April 2019

Ankyrin-based targeting pathway regulates human sinoatrial node automaticity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

SA node cell to atrial cardiac muscle cell communication

3 references

8 April 2019

Ankyrin-B mutation causes type 4 long-QT cardiac arrhythmia and sudden cardiac death

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

8 April 2019

Dysfunction in ankyrin-B-dependent ion channel and transporter targeting causes human sinus node disease

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

8 April 2019

Defects in ankyrin-based membrane protein targeting pathways underlie atrial fibrillation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

membrane depolarization during SA node cell action potential

1 reference

8 April 2019

Ankyrin-based targeting pathway regulates human sinoatrial node automaticity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

atrial cardiac muscle cell to AV node cell communication

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

regulation of cardiac muscle contraction

1 reference

8 April 2019

A cardiac arrhythmia syndrome caused by loss of ankyrin-B function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

protein localization to endoplasmic reticulum

1 reference

8 April 2019

A cardiac arrhythmia syndrome caused by loss of ankyrin-B function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

response to methylmercury

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

regulation of heart rate by cardiac conduction

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

8 April 2019

Defining the cellular phenotype of "ankyrin-B syndrome" variants: human ANK2 variants associated with clinical phenotypes display a spectrum of activities in cardiomyocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

8 April 2019

A cardiac arrhythmia syndrome caused by loss of ankyrin-B function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

8 April 2019

Ankyrin-B mutation causes type 4 long-QT cardiac arrhythmia and sudden cardiac death

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

8 April 2019

Defects in ankyrin-based membrane protein targeting pathways underlie atrial fibrillation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

atrial septum development

1 reference

8 April 2019

Dysfunction in ankyrin-B-dependent ion channel and transporter targeting causes human sinus node disease

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

regulation of calcium ion transmembrane transporter activity

1 reference

8 April 2019

Defects in ankyrin-based membrane protein targeting pathways underlie atrial fibrillation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

regulation of atrial cardiac muscle cell action potential

1 reference

8 April 2019

Ankyrin-B mutation causes type 4 long-QT cardiac arrhythmia and sudden cardiac death

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

T-tubule organization

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

positive regulation of calcium ion transport

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

regulation of ventricular cardiac muscle cell membrane repolarization

1 reference

8 April 2019

Dysfunction in ankyrin-B-dependent ion channel and transporter targeting causes human sinus node disease

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

cytoskeleton organization

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

protein localization to plasma membrane

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

protein localization to plasma membrane

3 references

8 April 2019

Defects in ankyrin-based membrane protein targeting pathways underlie atrial fibrillation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

8 April 2019

Targeting and stability of Na/Ca exchanger 1 in cardiomyocytes requires direct interaction with the membrane adaptor ankyrin-B

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01484

http://purl.uniprot.org/uniprot/Q01484

IBA

exact match

1 reference

Transporter Classification Database ID

Identifiers.org

Identifiers

1 reference

30 May 2020

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9 August 2016

language of work or name

1 reference

9 August 2016

language of work or name

1 reference

9 August 2016

language of work or name

English

8.A.28.1.1

2 references

Transporter Classification database

retrieved

13 March 2020