(Q21100532)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O14958

calsequestrin

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O14958

Calsequestrin, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

http://www.ebi.ac.uk/QuickGO/annotations?protein=O14958&geneProductId=UniProtKB:O14958

5 references

27 March 2018

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O14958&geneProductId=UniProtKB:O14958

27 March 2018

Characterization of human cardiac calsequestrin and its deleterious mutants

http://www.ebi.ac.uk/QuickGO/annotations?protein=O14958&geneProductId=UniProtKB:O14958

27 March 2018

Clinical phenotype and functional characterization of CASQ2 mutations associated with catecholaminergic polymorphic ventricular tachycardia

http://www.ebi.ac.uk/QuickGO/annotations?protein=O14958&geneProductId=UniProtKB:O14958

27 March 2018

Abnormal interactions of calsequestrin with the ryanodine receptor calcium release channel complex linked to exercise-induced sudden cardiac death

http://www.ebi.ac.uk/QuickGO/annotations?protein=O14958&geneProductId=UniProtKB:O14958

protein homodimerization activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14958

ISS

metal ion binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14958

1 reference

8 April 2019

calcium-dependent protein binding

1 reference

8 April 2019

Calsequestrin mutant D307H exhibits depressed binding to its protein targets and a depressed response to calcium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14958

protein binding

IPI

1 reference

8 April 2019

Role of Junctin protein interactions in cellular dynamics of calsequestrin polymer upon calcium perturbation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14958

IPI

calcium ion binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14958

6 references

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14958

8 April 2019

Characterization of human cardiac calsequestrin and its deleterious mutants

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14958

8 April 2019

Abnormal interactions of calsequestrin with the ryanodine receptor calcium release channel complex linked to exercise-induced sudden cardiac death

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14958

8 April 2019

Clinical phenotype and functional characterization of CASQ2 mutations associated with catecholaminergic polymorphic ventricular tachycardia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14958

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14958

cell component

cytoplasm

1 reference

8 April 2019

Role of Junctin protein interactions in cellular dynamics of calsequestrin polymer upon calcium perturbation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14958

voltage-gated calcium channel complex

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O14958&geneProductId=UniProtKB:O14958

ISS

calcium channel complex

1 reference

8 April 2019

Junctin and the histidine-rich Ca2+ binding protein: potential roles in heart failure and arrhythmogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14958

intracellular anatomical structure

1 reference

27 March 2018

Clinical phenotype and functional characterization of CASQ2 mutations associated with catecholaminergic polymorphic ventricular tachycardia

http://www.ebi.ac.uk/QuickGO/annotations?protein=O14958&geneProductId=UniProtKB:O14958

junctional sarcoplasmic reticulum membrane

1 reference

8 April 2019

Protein protein interactions between triadin and calsequestrin are involved in modulation of sarcoplasmic reticulum calcium release in cardiac myocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14958

sarcoplasmic reticulum membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14958

1 reference

8 April 2019

junctional membrane complex

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14958

sarcoplasmic reticulum lumen

http://www.ebi.ac.uk/QuickGO/annotations?protein=O14958&geneProductId=UniProtKB:O14958

3 references

27 March 2018

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O14958&geneProductId=UniProtKB:O14958

27 March 2018

Clinical phenotype and functional characterization of CASQ2 mutations associated with catecholaminergic polymorphic ventricular tachycardia

http://www.ebi.ac.uk/QuickGO/annotations?protein=O14958&geneProductId=UniProtKB:O14958

IC

Z discdkac

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14958

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14958

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14958

sarcoplasmic reticulum lumen

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14958

4 references

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14958

8 April 2019

Clinical phenotype and functional characterization of CASQ2 mutations associated with catecholaminergic polymorphic ventricular tachycardia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14958

IC

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14958

regulation of cardiac conduction

biological process

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14958

1 reference

8 April 2019

cardiac muscle contraction

1 reference

8 April 2019

Clinical phenotype and functional characterization of CASQ2 mutations associated with catecholaminergic polymorphic ventricular tachycardia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14958

regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion

Clinical phenotype and functional characterization of CASQ2 mutations associated with catecholaminergic polymorphic ventricular tachycardia

3 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14958

1 January 2018

Abnormal interactions of calsequestrin with the ryanodine receptor calcium release channel complex linked to exercise-induced sudden cardiac death

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14958

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14958

regulation of heart rate

Calsequestrin mutant D307H exhibits depressed binding to its protein targets and a depressed response to calcium

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14958

8 April 2019

Abnormal interactions of calsequestrin with the ryanodine receptor calcium release channel complex linked to exercise-induced sudden cardiac death

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14958

8 April 2019

Clinical phenotype and functional characterization of CASQ2 mutations associated with catecholaminergic polymorphic ventricular tachycardia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14958

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14958

detection of calcium ion

1 reference

8 April 2019

Role of Junctin protein interactions in cellular dynamics of calsequestrin polymer upon calcium perturbation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14958

ion transmembrane transport

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14958

1 reference

8 April 2019

sequestering of calcium ion

Clinical phenotype and functional characterization of CASQ2 mutations associated with catecholaminergic polymorphic ventricular tachycardia

2 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14958

8 April 2019

Abnormal interactions of calsequestrin with the ryanodine receptor calcium release channel complex linked to exercise-induced sudden cardiac death

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14958

cellular response to caffeine

1 reference

8 April 2019

Clinical phenotype and functional characterization of CASQ2 mutations associated with catecholaminergic polymorphic ventricular tachycardia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14958

regulation of cell communication by electrical coupling

1 reference

8 April 2019

Clinical phenotype and functional characterization of CASQ2 mutations associated with catecholaminergic polymorphic ventricular tachycardia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14958

sarcomere organization

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14958

striated muscle contraction

1 reference

8 April 2019

Cloning of the genes encoding mouse cardiac and skeletal calsequestrins: expression pattern during embryogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14958

Purkinje myocyte to ventricular cardiac muscle cell signaling

NAS

1 reference

8 April 2019

Calsequestrin 2 and arrhythmias

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14958

regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion

NAS

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14958

regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion

Abnormal interactions of calsequestrin with the ryanodine receptor calcium release channel complex linked to exercise-induced sudden cardiac death

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14958

8 April 2019

Clinical phenotype and functional characterization of CASQ2 mutations associated with catecholaminergic polymorphic ventricular tachycardia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14958

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14958

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14958

Calsequestrin, conserved site

has part(s)

1 reference

InterPro Release 71.0