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Chloride voltage-gated channel Ka
mammalian protein found in Homo sapiens
chloride channel, kidney, A
ClC-K1
CLCNKA
chloride channel Ka
chloride channel, voltage-sensitive Ka
chloride channel protein ClC-Ka
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
P51800
part of
chloride channel, core
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P51800
Chloride channel ClC-K
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P51800
CBS domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Homo sapiens
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
P51800
encoded by
CLCNKA
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
P51800
molecular function
metal ion binding
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P51800
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51800
determination method
IEA
voltage-gated ion channel activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P51800
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51800
determination method
IEA
chloride channel activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P51800
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51800
determination method
IEA
voltage-gated chloride channel activity
determination method
IBA
IEA
TAS
4 references
retrieved
31 January 2018
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P51800&geneProductId=UniProtKB:P51800
determination method
TAS
retrieved
31 January 2018
stated in
Two highly homologous members of the ClC chloride channel family in both rat and human kidney
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P51800&geneProductId=UniProtKB:P51800
determination method
TAS
retrieved
31 January 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P51800&geneProductId=UniProtKB:P51800
determination method
IEA
retrieved
31 January 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P51800&geneProductId=UniProtKB:P51800
determination method
IBA
identical protein binding
determination method
IPI
1 reference
retrieved
8 April 2019
stated in
The structure of the cytoplasmic domain of the chloride channel ClC-Ka reveals a conserved interaction interface
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51800
determination method
IPI
voltage-gated chloride channel activity
determination method
IEA
TAS
2 references
retrieved
8 April 2019
stated in
Two highly homologous members of the ClC chloride channel family in both rat and human kidney
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51800
determination method
TAS
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51800
determination method
IEA
cell component
integral component of membrane
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P51800
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51800
determination method
IEA
plasma membrane
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51800
determination method
TAS
integral component of plasma membrane
determination method
TAS
1 reference
retrieved
31 January 2018
stated in
Two highly homologous members of the ClC chloride channel family in both rat and human kidney
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P51800&geneProductId=UniProtKB:P51800
determination method
TAS
chloride channel complex
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P51800
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51800
determination method
IEA
membrane
determination method
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P51800
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51800
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51800
determination method
IEA
integral component of plasma membrane
determination method
IBA
TAS
2 references
retrieved
8 April 2019
stated in
Two highly homologous members of the ClC chloride channel family in both rat and human kidney
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51800
determination method
TAS
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51800
determination method
IBA
biological process
ion transmembrane transport
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51800
determination method
TAS
chloride transport
determination method
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P51800
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51800
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51800
determination method
IEA
excretion
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
Two highly homologous members of the ClC chloride channel family in both rat and human kidney
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51800
determination method
TAS
regulation of ion transmembrane transport
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P51800
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51800
determination method
IEA
ion transport
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P51800
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51800
determination method
IEA
transmembrane transport
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51800
determination method
IEA
chloride transmembrane transport
determination method
IBA
1 reference
retrieved
31 January 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P51800&geneProductId=UniProtKB:P51800
determination method
IBA
chloride transmembrane transport
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51800
determination method
IEA
physically interacts with
niflumic acid
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
2439
language of work or name
English
retrieved
17 August 2016
DIDS
has use
channel blocker
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
4177
language of work or name
English
retrieved
17 August 2016
has part(s)
CBS domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P51800
Identifiers
RefSeq protein ID
NP_001036169
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
1187
NP_001244068
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
1187
NP_004061
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
1187
UniProt protein ID
P51800
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
P51800
Ensembl protein ID
ENSP00000332771
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000332771
ENSP00000364844
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000364844
ENSP00000414445
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000414445
PDB structure ID
2PFI
1 reference
stated in
UniProt
UniProt protein ID
P51800
retrieved
9 August 2016
language of work or name
English
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