(Q21100963)

http://www.ebi.ac.uk/interpro/protein/Q9HB75

Leucine-rich repeat domain superfamily

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9HB75

Death-like domain superfamily

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9HB75

Death domain, protein family

1 reference

ZU5 domain, protein family

1 reference

Leucine-rich repeat, typical subtype, protein family

1 reference

Leucine-rich repeat, protein family

1 reference

LRDD, a novel leucine rich repeat and death domain containing protein

1 reference

13 November 2019

1 reference

13 November 2019

death receptor binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HB75

5 references

8 April 2019

The PIDDosome, a protein complex implicated in activation of caspase-2 in response to genotoxic stress

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HB75

8 April 2019

Functional connection between p53 and caspase-2 is essential for apoptosis induced by DNA damage

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HB75

8 April 2019

Towards a proteome-scale map of the human protein–protein interaction network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HB75

8 April 2019

An empirical framework for binary interactome mapping

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HB75

8 April 2019

Autoproteolysis of PIDD marks the bifurcation between pro-death caspase-2 and pro-survival NF-kappaB pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HB75

volume-sensitive anion channel activity

IPI

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HB75

Autoproteolysis of PIDD marks the bifurcation between pro-death caspase-2 and pro-survival NF-kappaB pathway

IBA

endopeptidase activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HB75

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HB75

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HB75

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HB75

3 references

27 March 2018

Caspase-2-mediated cleavage of Mdm2 creates a p53-induced positive feedback loop

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9HB75&geneProductId=UniProtKB:Q9HB75

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9HB75&geneProductId=UniProtKB:Q9HB75

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9HB75&geneProductId=UniProtKB:Q9HB75

2 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HB75

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HB75

4 references

10 September 2018

Caspase-2-mediated cleavage of Mdm2 creates a p53-induced positive feedback loop

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9HB75&geneProductId=UniProtKB:Q9HB75

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9HB75&geneProductId=UniProtKB:Q9HB75

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9HB75&geneProductId=UniProtKB:Q9HB75

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9HB75&geneProductId=UniProtKB:Q9HB75

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HB75

3 references

8 April 2019

Caspase-2-mediated cleavage of Mdm2 creates a p53-induced positive feedback loop

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HB75

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HB75

8 April 2019

Autoproteolysis of PIDD marks the bifurcation between pro-death caspase-2 and pro-survival NF-kappaB pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HB75

5 references

8 April 2019

Caspase-2-mediated cleavage of Mdm2 creates a p53-induced positive feedback loop

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HB75

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HB75

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HB75

8 April 2019

Autoproteolysis of PIDD marks the bifurcation between pro-death caspase-2 and pro-survival NF-kappaB pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HB75

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HB75

positive regulation of extrinsic apoptotic signaling pathway via death domain receptors

IBA

biological process

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HB75

2 references

positive regulation of extrinsic apoptotic signaling pathway

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HB75

DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

1 reference

8 April 2019

Caspase-2-mediated cleavage of Mdm2 creates a p53-induced positive feedback loop

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HB75

negative regulation of apoptotic process

IMP

1 reference

8 April 2019

Caspase-2-mediated cleavage of Mdm2 creates a p53-induced positive feedback loop

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HB75

positive regulation of apoptotic signaling pathway

IMP

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HB75

activation of cysteine-type endopeptidase activity involved in apoptotic process

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9HB75&geneProductId=UniProtKB:Q9HB75

positive regulation of NF-kappaB transcription factor activity

1 reference

8 April 2019

No death without life: vital functions of apoptotic effectors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HB75

positive regulation of apoptotic process

TAS

1 reference

8 April 2019

No death without life: vital functions of apoptotic effectors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HB75

regulation of apoptotic process

TAS

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HB75

inorganic anion transport

TAS

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HB75

anion transmembrane transport

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HB75

3 references

8 April 2019

Autoproteolysis of PIDD marks the bifurcation between pro-death caspase-2 and pro-survival NF-kappaB pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HB75

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HB75

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HB75

Autoproteolysis of PIDD marks the bifurcation between pro-death caspase-2 and pro-survival NF-kappaB pathway

protein autoprocessing

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HB75

regulation of I-kappaB kinase/NF-kappaB signaling

IDA

1 reference

8 April 2019

Autoproteolysis of PIDD marks the bifurcation between pro-death caspase-2 and pro-survival NF-kappaB pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HB75

extrinsic apoptotic signaling pathway via death domain receptors

IMP

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HB75

apoptotic signaling pathway

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HB75

extrinsic apoptotic signaling pathway

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HB75