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Dual specificity tyrosine phosphorylation regulated kinase 1B
mammalian protein found in Homo sapiens
dual specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
dual specificity tyrosine-phosphorylation-regulated kinase 1B
mirk protein kinase
DYRK1B
minibrain-related kinase
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q9Y463
part of
Protein kinase-like domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9Y463
Protein kinase domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Protein kinase, ATP binding site, protein family
1 reference
based on heuristic
inferred from protein domain or family
Serine/threonine-protein kinase, active site, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Homo sapiens
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q9Y463
encoded by
DYRK1B
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q9Y463
molecular function
transferase activity
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9Y463
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y463
determination method
IEA
protein kinase activity
determination method
IDA
IEA
TAS
3 references
retrieved
9 May 2019
stated in
Cloning and characterization of DYRK1B, a novel member of the DYRK family of protein kinases
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y463
determination method
TAS
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y463
determination method
IEA
retrieved
9 May 2019
stated in
Mirk protein kinase is activated by MKK3 and functions as a transcriptional activator of HNF1alpha
GOA
curator
UniProt
UniProt protein ID
Q9Y463
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y463
determination method
IDA
transcription coactivator activity
determination method
IDA
1 reference
retrieved
9 May 2019
stated in
Mirk protein kinase is activated by MKK3 and functions as a transcriptional activator of HNF1alpha
GOA
curator
UniProt
UniProt protein ID
Q9Y463
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y463
determination method
IDA
protein serine/threonine/tyrosine kinase activity
determination method
IEA
2 references
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9Y463
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y463
determination method
IEA
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y463
determination method
IEA
protein serine/threonine kinase activity
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9Y463
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y463
determination method
IEA
protein tyrosine kinase activity
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9Y463
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y463
determination method
IEA
nucleotide binding
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9Y463
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y463
determination method
IEA
protein binding
determination method
IPI
7 references
retrieved
9 May 2019
stated in
Mirk protein kinase is activated by MKK3 and functions as a transcriptional activator of HNF1alpha
GOA
curator
UniProt
UniProt protein ID
Q9Y463
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y463
determination method
IPI
retrieved
9 May 2019
stated in
Phosphorylation of Ser640 in Muscle Glycogen Synthase by DYRK Family Protein Kinases
GOA
curator
UniProt
UniProt protein ID
Q9Y463
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y463
determination method
IPI
retrieved
9 May 2019
stated in
A High-Density Map for Navigating the Human Polycomb Complexome
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y463
determination method
IPI
retrieved
9 May 2019
stated in
Mirk protein kinase is activated by MKK3 and functions as a transcriptional activator of HNF1alpha
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y463
determination method
IPI
retrieved
9 May 2019
stated in
The protein interaction landscape of the human CMGC kinase group
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y463
determination method
IPI
retrieved
9 May 2019
stated in
Serine/Threonine Kinase Mirk/Dyrk1B Is an Inhibitor of Epithelial Cell Migration and Is Negatively Regulated by the Met Adaptor Ran-binding Protein M
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y463
determination method
IPI
retrieved
9 May 2019
stated in
The WD40-repeat protein Han11 functions as a scaffold protein to control HIPK2 and MEKK1 kinase functions
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y463
determination method
IPI
ATP binding
determination method
IEA
2 references
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9Y463
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y463
determination method
IEA
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y463
determination method
IEA
kinase activity
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9Y463
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y463
determination method
IEA
cell component
nucleus
determination method
IDA
IEA
TAS
3 references
retrieved
9 May 2019
stated in
Cloning and characterization of DYRK1B, a novel member of the DYRK family of protein kinases
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y463
determination method
TAS
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9Y463
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y463
determination method
IEA
retrieved
9 May 2019
stated in
GOA
curator
Human Protein Atlas
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y463
determination method
IDA
biological process
positive regulation of transcription, DNA-templated
determination method
IDA
1 reference
retrieved
9 May 2019
stated in
Mirk protein kinase is activated by MKK3 and functions as a transcriptional activator of HNF1alpha
GOA
curator
UniProt
UniProt protein ID
Q9Y463
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y463
determination method
IDA
protein phosphorylation
determination method
IDA
IEA
TAS
3 references
retrieved
9 May 2019
stated in
Cloning and characterization of DYRK1B, a novel member of the DYRK family of protein kinases
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y463
determination method
TAS
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y463
determination method
IEA
retrieved
9 May 2019
stated in
Mirk protein kinase is activated by MKK3 and functions as a transcriptional activator of HNF1alpha
GOA
curator
UniProt
UniProt protein ID
Q9Y463
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y463
determination method
IDA
peptidyl-tyrosine phosphorylation
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y463
determination method
IEA
myoblast fusion
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y463
determination method
IEA
adipose tissue development
determination method
IMP
1 reference
retrieved
9 May 2019
stated in
A form of the metabolic syndrome associated with mutations in DYRK1B
GOA
curator
UniProt
UniProt protein ID
Q9Y463
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y463
determination method
IMP
phosphorylation
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9Y463
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y463
determination method
IEA
protein autophosphorylation
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y463
determination method
IEA
has part(s)
serine/threonine-protein kinase, active site
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9Y463
protein kinase, ATP binding site
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9Y463
protein kinase domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9Y463
Identifiers
RefSeq protein ID
NP_004705
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
9149
NP_006474
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
9149
NP_006475
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
9149
XP_005259455
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
9149
UniProt protein ID
Q9Y463
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q9Y463
Ensembl protein ID
ENSP00000221803
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000221803
ENSP00000312789
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000312789
ENSP00000403182
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000403182
ENSP00000469863
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000469863
ENSP00000472941
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000472941
ENSP00000485915
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000485915
ENSP00000486377
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000486377
ENSP00000486839
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000486839
ENSP00000487313
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000487313
ENSP00000487539
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000487539
ENSP00000471609
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000471609
ENSP00000486264
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000486264
ENSP00000472861
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000472861
ENSP00000486913
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000486913
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