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(Q21101082)
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English
Death effector domain containing 2
mammalian protein found in Homo sapiens
FADD-like anti-apoptotic molecule 3
DED-containing protein FLAME-3
DNA-binding death effector domain-containing protein 2
DEDD2
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q8WXF8
part of
Death-like domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q8WXF8
Death effector domain-containing protein
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q8WXF8
Death effector domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Homo sapiens
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q8WXF8
encoded by
DEDD2
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q8WXF8
molecular function
DNA binding
determination method
IBA
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8WXF8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WXF8
determination method
IEA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WXF8
determination method
IBA
signaling receptor complex adaptor activity
determination method
NAS
1 reference
retrieved
8 April 2019
stated in
Identification and characterization of DEDD2, a death effector domain-containing protein
GOA
curator
UniProt
UniProt protein ID
Q8WXF8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WXF8
determination method
NAS
protein binding
determination method
IPI
1 reference
retrieved
8 April 2019
stated in
Identification and characterization of DEDD2, a death effector domain-containing protein
GOA
curator
UniProt
UniProt protein ID
Q8WXF8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WXF8
determination method
IPI
cell component
nucleus
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8WXF8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WXF8
determination method
IEA
nucleolus
determination method
IEA
IDA
2 references
retrieved
24 April 2018
stated in
GOA
curator
UniProt
UniProt protein ID
Q8WXF8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8WXF8&geneProductId=UniProtKB:Q8WXF8
determination method
IEA
retrieved
24 April 2018
stated in
Identification and characterization of DEDD2, a death effector domain-containing protein
GOA
curator
UniProt
UniProt protein ID
Q8WXF8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8WXF8&geneProductId=UniProtKB:Q8WXF8
determination method
IDA
nucleolus
determination method
IBA
IDA
IEA
3 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8WXF8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WXF8
determination method
IEA
retrieved
8 April 2019
stated in
Identification and characterization of DEDD2, a death effector domain-containing protein
GOA
curator
UniProt
UniProt protein ID
Q8WXF8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WXF8
determination method
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WXF8
determination method
IBA
biological process
regulation of apoptotic process
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WXF8
determination method
IEA
rRNA catabolic process
determination method
NAS
1 reference
retrieved
8 April 2019
stated in
Identification and characterization of DEDD2, a death effector domain-containing protein
GOA
curator
UniProt
UniProt protein ID
Q8WXF8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WXF8
determination method
NAS
positive regulation of extrinsic apoptotic signaling pathway
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Identification and characterization of DEDD2, a death effector domain-containing protein
GOA
curator
UniProt
UniProt protein ID
Q8WXF8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WXF8
determination method
IMP
RNA processing
determination method
NAS
1 reference
retrieved
8 April 2019
stated in
Identification and characterization of DEDD2, a death effector domain-containing protein
GOA
curator
UniProt
UniProt protein ID
Q8WXF8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WXF8
determination method
NAS
intracellular signal transduction
determination method
NAS
1 reference
retrieved
8 April 2019
stated in
Identification and characterization of DEDD2, a death effector domain-containing protein
GOA
curator
UniProt
UniProt protein ID
Q8WXF8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WXF8
determination method
NAS
negative regulation of transcription, DNA-templated
determination method
NAS
1 reference
retrieved
8 April 2019
stated in
Identification and characterization of DEDD2, a death effector domain-containing protein
GOA
curator
UniProt
UniProt protein ID
Q8WXF8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WXF8
determination method
NAS
regulation of transcription, DNA-templated
determination method
IEA
1 reference
retrieved
24 April 2018
stated in
GOA
curator
UniProt
UniProt protein ID
Q8WXF8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8WXF8&geneProductId=UniProtKB:Q8WXF8
determination method
IEA
cellular homeostasis
determination method
NAS
1 reference
retrieved
8 April 2019
stated in
Identification and characterization of DEDD2, a death effector domain-containing protein
GOA
curator
UniProt
UniProt protein ID
Q8WXF8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WXF8
determination method
NAS
apoptotic nuclear changes
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
Identification and characterization of DEDD2, a death effector domain-containing protein
GOA
curator
UniProt
UniProt protein ID
Q8WXF8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WXF8
determination method
IDA
extrinsic apoptotic signaling pathway via death domain receptors
determination method
IMP
1 reference
retrieved
24 April 2018
stated in
Identification and characterization of DEDD2, a death effector domain-containing protein
GOA
curator
UniProt
UniProt protein ID
Q8WXF8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8WXF8&geneProductId=UniProtKB:Q8WXF8
determination method
IMP
transcription, DNA-templated
determination method
IEA
1 reference
retrieved
24 April 2018
stated in
GOA
curator
UniProt
UniProt protein ID
Q8WXF8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8WXF8&geneProductId=UniProtKB:Q8WXF8
determination method
IEA
apoptotic process
determination method
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8WXF8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WXF8
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WXF8
determination method
IEA
extrinsic apoptotic signaling pathway via death domain receptors
determination method
IBA
IMP
2 references
retrieved
8 April 2019
stated in
Identification and characterization of DEDD2, a death effector domain-containing protein
GOA
curator
UniProt
UniProt protein ID
Q8WXF8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WXF8
determination method
IMP
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WXF8
determination method
IBA
has part(s)
Death effector domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q8WXF8
Identifiers
RefSeq protein ID
NP_001257543
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
162989
NP_001257544
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
162989
NP_579874
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
162989
XP_011524871
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
162989
XP_011524873
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
162989
XP_011524874
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
162989
XP_016881891
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
162989
XP_016881892
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
162989
XP_024307168
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
162989
UniProt protein ID
Q8WXF8
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q8WXF8
Ensembl protein ID
ENSP00000336972
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000336972
ENSP00000470082
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000470082
ENSP00000471512
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000471512
ENSP00000469233
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000469233
ENSP00000469898
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000469898
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