Wikidata

(Q21101117)

English

Ubiquitin like with PHD and ring finger domains 1

mammalian protein found in Homo sapiens

  • HuNp95
  • nuclear protein 95
  • hUHRF1
  • RING-type E3 ubiquitin transferase UHRF1
  • nuclear phosphoprotein 95
  • transcription factor ICBP90
  • Ubiquitin-like-containing PHD and RING finger domains protein 1
  • nuclear zinc finger protein Np95
  • UHRF1
  • ubiquitin-like PHD and RING finger domain-containing protein 1
  • E3 ubiquitin-protein ligase UHRF1
  • inverted CCAAT box-binding protein of 90 kDa
  • RING finger protein 106
  • hNp95
In more languages

Statements

molecular function
protein binding
determination method
IPI
6 references
retrieved
8 April 2019
stated in
The epigenetic regulator UHRF1 promotes ubiquitination-mediated degradation of the tumor-suppressor protein promyelocytic leukemia protein
GOA
curator
UniProt
UniProt protein ID
Q96T88
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96T88
determination method
IPI
retrieved
8 April 2019
stated in
UHRF1 plays a role in maintaining DNA methylation in mammalian cells
GOA
curator
UniProt
UniProt protein ID
Q96T88
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96T88
determination method
IPI
retrieved
8 April 2019
stated in
The USP7/Dnmt1 complex stimulates the DNA methylation activity of Dnmt1 and regulates the stability of UHRF1
GOA
curator
UniProt
UniProt protein ID
Q96T88
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96T88
determination method
IPI
retrieved
8 April 2019
stated in
Np95 interacts with de novo DNA methyltransferases, Dnmt3a and Dnmt3b, and mediates epigenetic silencing of the viral CMV promoter in embryonic stem cells
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96T88
determination method
IPI
retrieved
8 April 2019
stated in
The interaction of the SRA domain of ICBP90 with a novel domain of DNMT1 is involved in the regulation of VEGF gene expression
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96T88
determination method
IPI
retrieved
8 April 2019
stated in
ICBP90, an E2F-1 target, recruits HDAC1 and binds to methyl-CpG through its SRA domain
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96T88
determination method
IPI
cell component
biological process

Identifiers

PDB structure ID
 
edit
    edit
      edit
        edit
          edit
            edit
              edit
                edit
                  edit
                    Retrieved from "https://www.wikidata.org/w/index.php?title=Q21101117&oldid=2022915765"